Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gouri Ranganathan"'
Autor:
Gouri Ranganathan, Resat Unal, Irina Pokrovskaya, Aiwei Yao-Borengasser, Bounleut Phanavanh, Beata Lecka-Czernik, Neda Rasouli, Philip A. Kern
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 11, Pp 2444-2450 (2006)
Acyl-coenzyme A:diacylglycerol transferase (DGAT), fatty acid synthetase (FAS), and LPL are three enzymes important in adipose tissue triglyceride accumulation. To study the relationship of DGAT1, FAS, and LPL with insulin, we examined adipose mRNA e
Externí odkaz:
https://doaj.org/article/3807b4e138304eff8509eff9db21e0c1
Publikováno v:
Journal of Lipids, Vol 2011 (2011)
Recent studies indicate that significant health benefits involving the regulation of signaling proteins result from the consumption of omega-3 polyunsaturated fatty acids (ω-3 PUFAs). Serum response factor (SRF) is involved in transcriptional regula
Externí odkaz:
https://doaj.org/article/4a65f864d4a4413f8a4629628fb6aa10
Publikováno v:
Adipocyte. 3:10-18
Objective To study whether there is an association between adiponectin and endoplasmic reticulum/sarcoplasmic reticulum (ERSR) stress. Research design Eleven-month-old male wild-type (WT) and adiponectin knockout (ADKO) mice were placed on chow or hi
Autor:
Jerome I. Rotter, Resat Unal, Preeti Tripathi, Philip A. Kern, Gouri Ranganathan, Irina D. Pokrovskaya, Mark O. Goodarzi
Publikováno v:
Atherosclerosis. 221:143-147
Objective A common gain-of-function LPL variant, LPLS447X, has favorable clinical features and involves a C→G base change at nucleotide 1595 of the LPL cDNA, along with a haplotype, which includes other non-coding SNPs. The mechanism for the LPL ga
Autor:
Neda Rasouli, Aiwei Yao-Borengasser, Vijayalakshmi Varma, Robert H. Coker, Gouri Ranganathan, Bounleut Phanavanh, Philip A. Kern
Publikováno v:
Metabolism. 60:1012-1020
Adipose triglyceride lipase (ATGL) catalyzes the first step in adipocyte and muscle triglyceride hydrolysis, and comparative gene identification-58 (CGI-58) is an essential cofactor. We studied the expression of ATGL and CGI-58 in human adipose and m
Autor:
Vijayalakshmi Varma, Gouri Ranganathan, Neda Rasouli, Aiwei Yao-Borengasser, Craig Labbate, Philip A. Kern, Resat Unal
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 95:2993-3001
Context: The study investigated the regulation of matrix metalloproteinases (MMP)-9 in obesity-associated insulin resistance in humans.Objectives: The objectives of the investigation were to study MMP-9 regulation by insulin resistance and pioglitazo
Autor:
Philip A. Kern, Gouri Ranganathan, Aiwei Yao-Borengasser, Negah Rassouli, Neda Rasouli, Robert E. McGehee, Resat Unal, Vijayalakshmi Varma, Bounleut Phanavanh, Angela M. Bodles
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 93:4431-4439
Context and Objective: Stearoyl-coenzyme A desaturase (SCD1) is the rate-limiting enzyme that converts palmitoyl- and stearoyl-coenzyme A to palmitoleoyl- and oleoyl-cownzyme A, respectively. SCD-deficient mice are protected from obesity, and the ob/
Autor:
Brett P. Monia, Philip A. Kern, Preeti Tripathi, Resat Unal, Gouri Ranganathan, Irina D. Pokrovskaya
Publikováno v:
Biochemical Journal. 413:315-322
Adipose LPL (lipoprotein lipase) plays an important role in regulating plasma triacylglycerols and lipid metabolism. We have previously demonstrated that PKCalpha (protein kinase Calpha) depletion inhibits LPL translation in 3T3-F442A adipocytes. Usi
Autor:
Neda Rasouli, Philip A. Kern, Angela M. Bodles, Randall J. Owens, Gouri Ranganathan, Anannya Banga
Publikováno v:
Metabolic Syndrome and Related Disorders. 6:103-111
Adiponectin, an adipocyte-specific secretory protein, is known to circulate as different isoforms in the blood stream.Using sucrose gradients and Western blotting on nondenaturing gels, adiponectin isoforms were examined in human serum, plasma, adipo
Autor:
Beata Lecka-Czernik, Neda Rasouli, Resat Unal, Gouri Ranganathan, Aiwei Yao-Borengasser, Irina D. Pokrovskaya, Philip A. Kern, Bounleut Phanavanh
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 11, Pp 2444-2450 (2006)
Acyl-coenzyme A:diacylglycerol transferase (DGAT), fatty acid synthetase (FAS), and LPL are three enzymes important in adipose tissue triglyceride accumulation. To study the relationship of DGAT1, FAS, and LPL with insulin, we examined adipose mRNA e