Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Gouri J Nanjangud"'
Autor:
Sai Harisha Rajanala, Romina Ghale, Subhiksha Nandakumar, Kalyani Chadalavada, Gwo-Shu Mary Lee, Konrad H Stopsack, Yu Chen, Gouri J Nanjangud, Goutam Chakraborty, Philip W Kantoff
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301989 (2024)
Somatic Y chromosome loss in hematopoietic cells is associated with higher mortality in men. However, the status of the Y chromosome in cancer tissue is not fully known due to technical limitations, such as difficulties in labelling and sequencing DN
Externí odkaz:
https://doaj.org/article/9f025f8d20d746c0a246657541807f95
Autor:
Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Publikováno v:
Cancer Discovery. :OF1-OF15
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d232aac4bf14933900750105086f2b
https://doi.org/10.1158/2159-8290.cd-22-0405
https://doi.org/10.1158/2159-8290.cd-22-0405
Autor:
Martin G. Dalin, Nora Katabi, Marta Persson, Ken-Wing Lee, Vladimir Makarov, Alexis Desrichard, Logan A. Walsh, Lyndsay West, Zaineb Nadeem, Deepa Ramaswami, Jonathan J. Havel, Fengshen Kuo, Kalyani Chadalavada, Gouri J. Nanjangud, Ian Ganly, Nadeem Riaz, Alan L. Ho, Cristina R. Antonescu, Ronald Ghossein, Göran Stenman, Timothy A. Chan, Luc G. T. Morris
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Myoepithelial carcinoma (MECA) is a rare aggressive salivary gland cancer. Here, the authors analyze the genomic landscape of MECA and identify a high prevalence of oncogenic gene fusions, primarily PLAG1 fusions, highlighting TGFBR3-PLAG1 as a poten
Externí odkaz:
https://doaj.org/article/ac5cf5be332f48df922f9b4c8c1e098f
Autor:
Timour Baslan, John P. Morris, Zhen Zhao, Jose Reyes, Yu-Jui Ho, Kaloyan M. Tsanov, Jonathan Bermeo, Sha Tian, Sean Zhang, Gokce Askan, Aslihan Yavas, Nicolas Lecomte, Amanda Erakky, Anna M. Varghese, Amy Zhang, Jude Kendall, Elena Ghiban, Lubomir Chorbadjiev, Jie Wu, Nevenka Dimitrova, Kalyani Chadalavada, Gouri J. Nanjangud, Chaitanya Bandlamudi, Yixiao Gong, Mark T. A. Donoghue, Nicholas D. Socci, Alex Krasnitz, Faiyaz Notta, Steve D. Leach, Christine A. Iacobuzio-Donahue, Scott W. Lowe
Publikováno v:
Nature. 608:795-802
Although p53 inactivation promotes genomic instability1 and presents a route to malignancy for more than half of all human cancers2,3, the patterns through which heterogenous TP53 (encoding human p53) mutant genomes emerge and influence tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d92e4faced4f3453550dbf42fecb004
https://doi.org/10.1038/s41586-022-05082-5
https://doi.org/10.1038/s41586-022-05082-5
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321acf5988c203cec453f0f9392a6cbb
https://doi.org/10.1158/2159-8290.c.6549768
https://doi.org/10.1158/2159-8290.c.6549768
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Generation of acquired resistance PDX model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b112c15ea1771670c6a5c8e6aa44819
https://doi.org/10.1158/2159-8290.22541925.v1
https://doi.org/10.1158/2159-8290.22541925.v1
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Characterization of acquired resistance in vitro models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f67ce7610e48806cbaecce32c2ecb5
https://doi.org/10.1158/2159-8290.22541934
https://doi.org/10.1158/2159-8290.22541934
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Oncoprint of baseline alterations in CRC patients who developed resistance to KRAS G12C and EGFR inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1e5f0b69f42344348c333a68349703
https://doi.org/10.1158/2159-8290.22541922
https://doi.org/10.1158/2159-8290.22541922
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
C106 resistant cells drug withdrawal and Patient #12 MSK-Impact data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721a27ac24ffaf19b9a34afef5d70fdb
https://doi.org/10.1158/2159-8290.22541916.v1
https://doi.org/10.1158/2159-8290.22541916.v1
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Patients Progression Cell Free DNA data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2103f98339db3653ec1f01ea60631758
https://doi.org/10.1158/2159-8290.22541910
https://doi.org/10.1158/2159-8290.22541910