A reliable transcriptomic risk-score applicable to formalin-fixed paraffin-embedded biopsies improves outcome prediction in localized prostate cancer.

Autor: Rade M; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Kreuz M; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Borkowetz A; Department of Urology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Sommer U; Institute of Pathology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Blumert C; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Füssel S; Department of Urology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Bertram C; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Löffler D; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Otto DJ; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.; Basic Science Division, Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA., Wöller LA; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Schimmelpfennig C; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Köhl U; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.; Institute of Clinical Immunology, University of Leipzig, Leipzig, Germany., Gottschling AC; Department of Urology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Hönscheid P; Institute of Pathology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Baretton GB; Institute of Pathology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Wirth M; Department of Urology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Thomas C; Department of Urology, Faculty of Medicine, University Hospital, Technische Universität Dresden, Dresden, Germany., Horn F; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Reiche K; Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany. kristin.reiche@izi.fraunhofer.de.; Institute of Clinical Immunology, University of Leipzig, Leipzig, Germany. kristin.reiche@izi.fraunhofer.de.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, 04105, Leipzig, Germany. kristin.reiche@izi.fraunhofer.de.

Publikováno v: Molecular medicine (Cambridge, Mass.) [Mol Med] 2024 Feb 01; Vol. 30 (1), pp. 19. Date of Electronic Publication: 2024 Feb 01.