HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry

Autor: Henriksen, EKK, Viken, MK, Wittig, M, Holm, K, Folseraas, T, Mucha, S, Melum, E, Hov, JR, Lazaridis, KN, Juran, BD, Chazouillères, O, Färkkilä, M, Gotthardt, DN, Invernizzi, P, Carbone, M, Hirschfield, GM, Rushbrook, SM, Goode, E, UK-PSC Consortium, Ponsioen, CY, Weersma, RK, Eksteen, B, Yimam, KK, Gordon, SC, Goldberg, D, Yu, L, Bowlus, CL, Franke, A, Lie, BA, Karlsen, TH

Publikováno v: HLA, vol 90, iss 4

Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotypes. Due to extensive linkage disequilibrium and multiple polymorphic candidate genes in the HLA complex, identifying the alleles responsibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8659da7c5aec11bb61dd5bbb2379e241
https://escholarship.org/uc/item/5cr1s258

Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities.

Autor: Goeppert B; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Folseraas T; Norwegian PSC Research Center Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; K.G. Jebsen Inflammation Research Center, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway., Roessler S; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Kloor M; Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany., Volckmar AL; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Endris V; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Buchhalter I; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.; Institute of Pathology, Omics IT and Data Management Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany., Stenzinger A; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Grzyb K; Department of Pathology, Oslo University Hospital, Oslo, Norway., Grimsrud MM; Norwegian PSC Research Center Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway., Gornicka B; Department of Pathology, Medical University of Warsaw, Warsaw, Poland., von Seth E; Department of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Reynolds GM; Center for Liver Research, NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham, United Kingdom., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel, Germany., Gotthardt DN; Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany., Mehrabi A; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany., Cheung A; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN., Verheij J; Department of Pathology, Academic Medical Center, Amsterdam, the Netherlands., Arola J; Department of Pathology, Haartman Institute and Huslab, Helsinki University Hospital, Helsinki, Finland., Mäkisalo H; Department of Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland., Eide TJ; Department of Pathology, Oslo University Hospital, Oslo, Norway., Weidemann S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Cheville JC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN., Mazza G; Division of Medicine, Institute for Liver and Digestive Health Royal Free Hospital, University College London, London, United Kingdom., Hirschfield GM; Center for Liver Research, NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham, United Kingdom.; University Hospital Birmingham, NHS Foundation Trust, Birmingham, United Kingdom., Ponsioen CY; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands., Bergquist A; Department of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Milkiewicz P; Liver and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland.; Translational Medicine Group, Pomeranian Medical University, Szczecin, Poland., Lazaridis KN; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN., Schramm C; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Manns MP; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Färkkilä M; Department of Gastroenterology & Hepatology, Helsinki University Hospital, Helsinki, Finland., Vogel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Boberg KM; Norwegian PSC Research Center Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; K.G. Jebsen Inflammation Research Center, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway., Schirmacher P; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Karlsen TH; Norwegian PSC Research Center Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.; K.G. Jebsen Inflammation Research Center, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2020 Oct; Vol. 72 (4), pp. 1253-1266. Date of Electronic Publication: 2020 Aug 19.

The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson's disease.

Autor: Glavind E; Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, DK-8200, Aarhus N, Denmark. emigla@rm.dk., Gotthardt DN; Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany., Pfeiffenberger J; Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany., Sandahl TD; Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, DK-8200, Aarhus N, Denmark., Bashlekova T; Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany., Willemoe GL; Department of Pathology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Hasselby JP; Department of Pathology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Weiss KH; Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany., Møller HJ; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark., Vilstrup H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, DK-8200, Aarhus N, Denmark., Lee WM; Division of Digestive and Liver Diseases, UT Southwestern Medical Center at Dallas, Dallas, TX, USA., Schilsky ML; Yale University Medical Center, New Haven, CT, 06520, USA., Ott P; Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, DK-8200, Aarhus N, Denmark., Grønbæk H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, 99 Palle Juul-Jensens Boulevard, DK-8200, Aarhus N, Denmark.

Publikováno v: Orphanet journal of rare diseases [Orphanet J Rare Dis] 2020 Jul 02; Vol. 15 (1), pp. 173. Date of Electronic Publication: 2020 Jul 02.

Biliary calprotectin, lactoferrin and dimeric pyruvate kinase after liver transplantation are associated with biliary damage and graft survival in a case-control study.

Autor: Rauber C; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany; Université Paris-Sud, Université Paris-Saclay, 91400 Paris, France; Gustave Roussy Cancer Campus (GRCC), 94800 Villejuif, France. Electronic address: conrad.rauber@gmx.de., Awad M; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Koschny R; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Sauer P; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Mehrabi A; Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Gath P; Department of Gastroenterology and Hepatology, Hospital Ludwigshafen, 67063 Ludwigshafen, Germany., Weiss KH; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Gotthardt DN; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany., Rupp C; Department of Gastroenterology, University Hospital Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany.

Publikováno v: Clinics and research in hepatology and gastroenterology [Clin Res Hepatol Gastroenterol] 2020 Feb; Vol. 44 (1), pp. 38-48. Date of Electronic Publication: 2019 Jun 11.

Multidrug-Resistant Bacteria and Disease Progression in Patients with End-Stage Liver Disease and after Liver Transplantation.

Autor: Friedrich K; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. . kilianfriedrich@gmx.de., Krempl J; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. Jessica.krempl@med.uni-heidelberg.de., Schamoni S; Department of Computational Linguistics, University of Heidelberg, Heidelberg, Germany. schamoni@cl.uni-heidelberg.de., Hippchen T; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. theresa.hippchen@med.uni-heidelberg.de., Pfeiffenberger J; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. jan.pfeiffenberger@med.uni-heidelberg.de., Rupp C; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. christian.rupp@med.uni-heidelberg.de., Gotthardt DN; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. daniel.gotthardt@med.uni-heidelberg.de., Houben P; Department of General, Visceral and Tansplant Surgery, University Hospital of Heidelberg, Heidelberg, Germany. philip.houben@med.uni-heidelberg.de., Von Haken R; Department of Anaesthesiology, University Hospital of Heidelberg, Heidelberg, Germany. Rebecca.vonhaken@med.uni-heidelberg.de., Heininger A; Department of Infectious Diseases, Medical Microbiology and Hygiene, Division Hospital and Environmental Hygiene, Heidelberg University Hospital, Heidelberg, Germany. alexandra.heininger@med.uni-heidelberg.de., Brenner T; Department of Anaesthesiology, University Hospital of Heidelberg, Heidelberg, Germany. thorsten.brenner@med.uni-heidelberg.de., Mehrabi A; Department of General, Visceral and Tansplant Surgery, University Hospital of Heidelberg, Heidelberg, Germany. arianeb.mehrabi@med.uni-heidelberg.de., Weiss KH; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany. karl-heinz.weiss@med.uni-heidelberg.de., Mieth M; Department of General, Visceral and Tansplant Surgery, University Hospital of Heidelberg, Heidelberg, Germany. markus.mieth@med.uni-heidelberg.de.

Publikováno v: Journal of gastrointestinal and liver diseases : JGLD [J Gastrointestin Liver Dis] 2019 Sep 01; Vol. 28 (3), pp. 303-310. Date of Electronic Publication: 2019 Sep 01.