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pro vyhledávání: '"Gottfried Wenke"'
Autor:
Gottfried Wenke, Alicia Regueiro-Ren, Roumyana Yordanova, Umesh Hanumegowda, John P. Corradi, Stephen P. Adams
Publikováno v:
Chemical research in toxicology. 23(4)
Drug-induced phospholipidosis (PLD) is an adaptive histologic alteration that is seen with various marketed drugs and often encountered during drug development. Various in silico and in vitro cell-based methods have been developed to predict the PLD-
Autor:
John A. Pople, Paul von Ragué Schleyer, Gottfried Wenke, Robert A. Whiteside, Mary-Beth Krogh-Jespersen, R. Krishnan
Publikováno v:
Journal of Computational Chemistry. 1:307-322
The geometries and energies of beryllium clusters up to Be5 are examined using ab initio molecular orbital theory. Allowances are made for electron correlation with Moller—Plesset perturbation theory to fourth order. Correlation is found to have a
Publikováno v:
Carcinogenesis. 5(9)
3-(Methylnitrosamino)propionitrile (MNPN) is formed in vitro under mild nitrosation conditions from the major areca alkaloid arecoline. It appears likely that MNPN is generated during betel quid chewing especially when tobacco is added to the quid. U
Autor:
Gottfried Wenke, Dietrich Hoffmann
Publikováno v:
Carcinogenesis. 4(2)
Betel quid chewing is strongly associated with cancer of the oral cavity. Extracts of betel quid are tumorigenic in the experimental animal, but thus far, not a single carcinogen has been detected in the tobacco free quid. This study is based on the