Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gottfried Mieskes"'
Autor:
Christian Ducho, Reinhard Jahn, Stefan Koppermann, Gottfried Mieskes, Anatol P. Spork, Stephanie Schier Née Wohnig, Nicolas Gisch
Publikováno v:
Chemistry-A European Journal
The membrane protein translocase I (MraY) is a key enzyme in bacterial peptidoglycan biosynthesis. It is therefore frequently discussed as a target for the development of novel antibiotics. The screening of compound libraries for the identification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc39ec076375d1a9253c8fc56f3924ec
https://pubmed.ncbi.nlm.nih.gov/27791327
https://pubmed.ncbi.nlm.nih.gov/27791327
Autor:
John E. Heuser, Mads Grønborg, Henning Urlaub, Reinhard Jahn, Shigeo Takamori, Bert L. de Groot, Frauke Gräter, Felix T. Wieland, Jochen S. Hub, Philippe Ringler, Shirley A. Müller, Katinka Stenius, Britta Brügger, Gottfried Mieskes, Jürgen Klingauf, Stephan Schenck, Matthew Holt, Yoshinori Moriyama, Dietmar Riedel, Burkhard Rammner, Edward A. Lemke, Helmut Grubmüller
Publikováno v:
Cell
Membrane traffic in eukaryotic cells involves transport of vesicles that bud from a donor compartment and fuse with an acceptor compartment. Common principles of budding and fusion have emerged, and many of the proteins involved in these events are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5be8e6b8415c3adb544d49367ffeed
https://doi.org/10.1016/j.cell.2006.10.030
https://doi.org/10.1016/j.cell.2006.10.030
Autor:
J. Fullekrug, W. Diekmann, P. Nguyen Van, Birte Sönnichsen, Gottfried Mieskes, D. G. Robinson
Publikováno v:
Journal of Cell Science. 107:2705-2717
Many soluble resident proteins of the endoplasmic reticulum share a COOH-terminal Lys-Asp-Glu-Leu (KDEL) sequence. Current opinion favours a model in which these proteins can escape from the endoplasmic reticulum (ER) by bulk flow and are recognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed76013f7370d3dc6c2d718d6bec5600
https://doi.org/10.1242/jcs.107.10.2705
https://doi.org/10.1242/jcs.107.10.2705
Publikováno v:
Biochemical Journal. 284:539-544
The effect of structural modifications of okadaic acid (OA), a polyether C38 fatty acid, was studied on its inhibitory activity toward type 1 and type 2A protein phosphatases (PP1 and PP2A) by using OA derivatives obtained either by isolation from na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67acb7e6104dbb8552f34f48e68fa92b
https://doi.org/10.1042/bj2840539
https://doi.org/10.1042/bj2840539
Autor:
Hans-Dieter Söling, Birte Sönnichsen, Gottfried Mieskes, Joachim Füllekrug, Ulrike Schäfer, Phuc Nguyen Van
Publikováno v:
FEBS letters. 404(1)
Residence of luminal ER proteins is mediated by a cyclic process which involves binding of escaped proteins to a KDEL receptor in a post-ER compartment and redistribution of the ligand-receptor complex back to the ER. We examined the relocation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2d39c228e3fc16d19a79c909555c07
https://pubmed.ncbi.nlm.nih.gov/9074641
https://pubmed.ncbi.nlm.nih.gov/9074641
Publikováno v:
ResearcherID
The patch-clamp technique was employed to investigate phosphorylation/dephosphorylation-dependent modulation of L-type Ca2+ channels in smooth-muscle cells isolated from human umbilical vein. Okadaic acid, an inhibitor of phosphoprotein phosphatases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dabd88152773b932692c0c42ae53bb
https://europepmc.org/articles/PMC1217650/
https://europepmc.org/articles/PMC1217650/
Publikováno v:
FEBS letters. 370(3)
The focal adhesion protein VASP, a possible link between signal transduction pathways and the microfilament system, is phosphorylated by both cAMP- and cGMP-dependent protein kinases in vitro and in intact cells. Here, the analysis of VASP dephosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4443b674d02c525e61314498ba8ec4d6
https://pubmed.ncbi.nlm.nih.gov/7656973
https://pubmed.ncbi.nlm.nih.gov/7656973
Autor:
Kiyoshi Isono, Keiichi Sasaki, Akira Takai, Takeshi Yasumoto, Minoru Isobe, H Nagai, Gottfried Mieskes
Several groups have reported that okadaic acid (OA) and some other tight-binding protein phosphatase inhibitors including microcystin-LR (MCLR), calyculin-A and tautomycin prevent each other from binding to protein phosphatase 2A (PP2A). In this pape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3721514e7119ad9563d6b0bebf84efd8
https://europepmc.org/articles/PMC1136572/
https://europepmc.org/articles/PMC1136572/
Autor:
P. Nguyen Van, K. Arseven, Birte Sönnichsen, J. Fullekrug, U. Wunsch, Gottfried Mieskes, Hans-Dieter Söling
Publikováno v:
Journal of cell science. 107
A cDNA encoding rat CaBP1 has been isolated and sequenced. The deduced polypeptide chain consists of 440 amino acids including two internal thioredoxin-like domains and a C-terminal KDEL retention/retrieval signal. Regarding the high degree of identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31136806981ffe5ead58d60f521986bc
https://pubmed.ncbi.nlm.nih.gov/7876340
https://pubmed.ncbi.nlm.nih.gov/7876340
Publikováno v:
Scopus-Elsevier
Okadaic acid (OA), a potent inhibitor of type-1 and type-2A protein phosphatases (PP1 and PP2A), has four hydroxyl groups at 2, 7, 24 and 27 positions (see Figure 1). By chemical treatment of OA we synthesized a derivative, in which the 27-hydroxyl g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188539667a73bde95a7ec8ef85def9ac
https://europepmc.org/articles/PMC1137933/
https://europepmc.org/articles/PMC1137933/