Catalytic asymmetric Mannich reactions of glycine derivatives with imines:A new approach to optically active alpha,beta-diamino acid derivatives

Autor: Bernardi, L., Gothelf, A.S., Hazell, R.G., Jørgensen, K.A.

Publikováno v: Bernardi, L, Gothelf, A S, Hazell, R G & Jørgensen, K A 2003, ' Catalytic asymmetric Mannich reactions of glycine derivatives with imines : A new approach to optically active alpha,beta-diamino acid derivatives ' J. Org. Chem., vol. 7, no. 68, pp. 2583-2591 .

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https://pure.au.dk/portal/da/publications/catalytic-asymmetric-mannich-reactions-of-glycine-derivatives-with-imines(c4f858e0-9560-11da-bee9-02004c4f4f50).html

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Catalytic asymmetric Mannich reactions of glycine derivatives with imines. A new approach to optically active alpha,beta-diamino acid derivatives

Autor: Karl Anker Joergensen, Luca Bernardi, Rita G. Hazell, Aase Sejr Gothelf

Publikováno v: The Journal of organic chemistry. 68(7)

Imines of glycine alkyl esters react with imines in a diastereo- and highly enantioselective Mannich reaction in the presence of chiral copper(I) complexes as the catalyst to give optically active alpha,beta-diamino acid derivatives. A series of imin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113034ed818c82ef9a68c0248d40f166
https://pubmed.ncbi.nlm.nih.gov/12662026