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Fertility protection during chemotherapy treatment by boosting the NAD(P) ⁺ metabolome.

Autor: Ho WJ; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia.; The Kinghorn Cancer Centre, St. Vincent's Hospital, Darlinghurst, NSW, Australia., Marinova MB; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Listijono DR; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Bertoldo MJ; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Richani D; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Kim LJ; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Brown A; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Riepsamen AH; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Cabot S; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Frost ER; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Bustamante S; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Kensington, NSW, 2052, Australia., Zhong L; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Kensington, NSW, 2052, Australia., Selesniemi K; Paul F Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA, USA., Wong D; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Madawala R; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Marchante M; IVI Foundation, Valencia, Spain.; Department of Pediatrics, Obstetrics and Gynaecology, Faculty of Medicine, University of Valencia, Valencia, Spain., Goss DM; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Li C; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia., Araki T; Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-higashi, Kodaira, Tokyo, 187-8502, Japan., Livingston DJ; Metro International Biotech, Worcester, MA, USA., Turner N; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia.; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia., Sinclair DA; Paul F Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA, USA., Walters KA; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Homer HA; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia.; Christopher Chen Oocyte Biology Laboratory, University of Queensland Centre for Clinical Research, Royal Brisbane & Women's Hospital, Herston, QLD, 4029, Australia., Gilchrist RB; School of Clinical Medicine, UNSW Sydney, Kensington, NSW, 2052, Australia., Wu LE; School of Biomedical Sciences, UNSW Sydney, Kensington, NSW, 2052, Australia. lindsay.wu@unsw.edu.au.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2024 Oct; Vol. 16 (10), pp. 2583-2618. Date of Electronic Publication: 2024 Aug 21.

Evaluation of an artificial intelligence-facilitated sperm detection tool in azoospermic samples for use in ICSI.

Autor: Goss DM; School of Biomedical Engineering, University of Technology Sydney, Sydney, New South Wales, Australia.; NeoGenix Biosciences Pty Ltd, Sydney, New South Wales, Australia.; IVFAustralia, Sydney, New South Wales, Australia., Vasilescu SA; School of Biomedical Engineering, University of Technology Sydney, Sydney, New South Wales, Australia.; NeoGenix Biosciences Pty Ltd, Sydney, New South Wales, Australia., Vasilescu PA; NeoGenix Biosciences Pty Ltd, Sydney, New South Wales, Australia., Cooke S; IVFAustralia, Sydney, New South Wales, Australia., Kim SH; IVFAustralia, Sydney, New South Wales, Australia.; University of New South Wales, Sydney, New South Wales, Australia., Sacks GP; School of Biomedical Engineering, University of Technology Sydney, Sydney, New South Wales, Australia.; IVFAustralia, Sydney, New South Wales, Australia.; University of New South Wales, Sydney, New South Wales, Australia., Gardner DK; NeoGenix Biosciences Pty Ltd, Sydney, New South Wales, Australia.; Melbourne IVF, Melbourne, Victoria, Australia., Warkiani ME; School of Biomedical Engineering, University of Technology Sydney, Sydney, New South Wales, Australia.; NeoGenix Biosciences Pty Ltd, Sydney, New South Wales, Australia.; Institute for Biomedical Materials & Devices (IBMD), University of Technology Sydney, Sydney, New South Wales, Australia.. Electronic address: majid.warkiani@uts.edu.au.

Publikováno v: Reproductive biomedicine online [Reprod Biomed Online] 2024 Jul; Vol. 49 (1), pp. 103910. Date of Electronic Publication: 2024 Feb 22.

Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice.

Autor: Habibalahi A; ARC Centre of Excellence Centre for Nanoscale Biophotonics, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Campbell JM; ARC Centre of Excellence Centre for Nanoscale Biophotonics, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Bertoldo MJ; Fertility & Research Centre, School of Clinical Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia.; School of Medical Sciences, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Mahbub SB; ARC Centre of Excellence Centre for Nanoscale Biophotonics, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Goss DM; School of Medical Sciences, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Ledger WL; Fertility & Research Centre, School of Clinical Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Gilchrist RB; Fertility & Research Centre, School of Clinical Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Wu LE; School of Medical Sciences, University of New South Wales Sydney, Sydney, NSW 2052, Australia., Goldys EM; ARC Centre of Excellence Centre for Nanoscale Biophotonics, University of New South Wales Sydney, Sydney, NSW 2052, Australia.

Publikováno v: Biomedicines [Biomedicines] 2022 Jun 29; Vol. 10 (7). Date of Electronic Publication: 2022 Jun 29.

NAD ⁺ Repletion Rescues Female Fertility during Reproductive Aging.

Autor: Bertoldo MJ; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Listijono DR; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Ho WJ; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Riepsamen AH; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Goss DM; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Richani D; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Jin XL; Human Reproduction Unit, Kolling Institute, Sydney Medical School, University of Sydney, St Leonards, NSW, Australia., Mahbub S; ARC Centre of Excellence in Nanoscale Biophotonics, UNSW Sydney, NSW, Australia., Campbell JM; ARC Centre of Excellence in Nanoscale Biophotonics, UNSW Sydney, NSW, Australia., Habibalahi A; ARC Centre of Excellence in Nanoscale Biophotonics, UNSW Sydney, NSW, Australia., Loh WN; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Youngson NA; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Maniam J; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Wong ASA; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Selesniemi K; Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston MA, USA; Jumpstart Fertility Pty Ltd., Sydney, NSW, Australia., Bustamante S; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Li C; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Zhao Y; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Marinova MB; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Kim LJ; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Lau L; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Wu RM; Graduate Entry Medical School, University of Limerick, Limerick, Republic of Ireland., Mikolaizak AS; Neuroscience Research Australia, Randwick, NSW, Australia., Araki T; Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan., Le Couteur DG; ANZAC Medical Research Institute, University of Sydney, Concord, NSW, Australia., Turner N; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Morris MJ; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Walters KA; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Goldys E; ARC Centre of Excellence in Nanoscale Biophotonics, UNSW Sydney, NSW, Australia., O'Neill C; Human Reproduction Unit, Kolling Institute, Sydney Medical School, University of Sydney, St Leonards, NSW, Australia., Gilchrist RB; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia., Sinclair DA; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia; Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston MA, USA. Electronic address: david_sinclair@hms.harvard.edu., Homer HA; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia; Christopher Chen Oocyte Biology Laboratory, University of Queensland Centre for Clinical Research, Royal Brisbane & Women's Hospital, Herston, QLD, Australia. Electronic address: h.homer@uq.edu.au., Wu LE; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia. Electronic address: lindsay.wu@unsw.edu.au.

Publikováno v: Cell reports [Cell Rep] 2020 Feb 11; Vol. 30 (6), pp. 1670-1681.e7.