Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.

Autor: Graelmann FJ; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Gondorf F; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Majlesain Y; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Niemann B; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Klepac K; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Gosejacob D; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Gottschalk M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Mayer M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Iriady I; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Hatzfeld P; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Lindenberg SK; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Wunderling K; Biochemistry & Cell Biology of Lipids, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Thiele C; Biochemistry & Cell Biology of Lipids, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Abdullah Z; Institute of Molecular Medicine and Experimental Immunology, University Hospital Bonn, University of Bonn, Germany., He W; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Hiller K; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Händler K; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany; Institute of Human Genetics, Universitätsklinikum Schleswig-Holstein, University of Lübeck and University of Kiel, 23562 Lübeck, Germany., Beyer MD; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Immunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases, Bonn, Germany., Ulas T; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Pfeifer A; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Esser C; IUF-Leibniz Research Institute for Environmental Medicine gGmbH, Düsseldorf, Germany., Weighardt H; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany; IUF-Leibniz Research Institute for Environmental Medicine gGmbH, Düsseldorf, Germany., Förster I; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany. Electronic address: irmgard.foerster@uni-bonn.de., Reverte-Salisa L; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany. Electronic address: laia@uni-bonn.de.

Publikováno v: Molecular metabolism [Mol Metab] 2024 Jul; Vol. 85, pp. 101963. Date of Electronic Publication: 2024 May 29.

Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β 1 and β 3 -adrenoceptor signalling.

Autor: Kannabiran SA; Institute of Pharmacology and Toxicology, University of Bonn, 53127, Bonn, Germany; Research Training Group 1873, University of Bonn, 53127, Bonn, Germany., Gosejacob D; Institute of Pharmacology and Toxicology, University of Bonn, 53127, Bonn, Germany. Electronic address: dominic.gosejacob@uni-bonn.de., Niemann B; Institute of Pharmacology and Toxicology, University of Bonn, 53127, Bonn, Germany; Bonn International Graduate School of Drug Sciences (BIGS DrugS), Germany., Nikolaev VO; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, D-20246, Hamburg, Germany. Electronic address: v.nikolaev@uke.de., Pfeifer A; Institute of Pharmacology and Toxicology, University of Bonn, 53127, Bonn, Germany; Research Training Group 1873, University of Bonn, 53127, Bonn, Germany; Bonn International Graduate School of Drug Sciences (BIGS DrugS), Germany. Electronic address: alexander.pfeifer@uni-bonn.de.

Publikováno v: Molecular metabolism [Mol Metab] 2020 Jul; Vol. 37, pp. 100986. Date of Electronic Publication: 2020 Apr 01.

Dietary rescue of lipotoxicity-induced mitochondrial damage in Peroxin19 mutants.

Autor: Sellin J; University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Bonn, Germany., Wingen C; University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Bonn, Germany., Gosejacob D; University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Bonn, Germany., Senyilmaz D; German Cancer Research Center, Signal Transduction in Cancer and Metabolism, Heidelberg, Germany., Hänschke L; University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Bonn, Germany., Büttner S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Meyer K; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Bano D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Nicotera P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Teleman AA; German Cancer Research Center, Signal Transduction in Cancer and Metabolism, Heidelberg, Germany., Bülow MH; University of Bonn, Life & Medical Sciences Institute (LIMES), Molecular Developmental Biology, Bonn, Germany.

Publikováno v: PLoS biology [PLoS Biol] 2018 Jun 19; Vol. 16 (6), pp. e2004893. Date of Electronic Publication: 2018 Jun 19 (Print Publication: 2018).

Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases.

Autor: Sellin J; LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn, Carl-Troll-Strasse 31, 53115 Bonn, Germany m.hoch@uni-bonn.de sellin@uni-bonn.de., Schulze H; LIMES-Institute, Program Unit Membrane Biology & Lipid Biochemistry, c/o Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany., Paradis M; LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn, Carl-Troll-Strasse 31, 53115 Bonn, Germany., Gosejacob D; LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn, Carl-Troll-Strasse 31, 53115 Bonn, Germany., Papan C; Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany., Shevchenko A; Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany., Psathaki OE; University of Osnabrück, Department of Zoology and Developmental Biology, Barbarastraße 11, 49076 Osnabrueck, Germany., Paululat A; University of Osnabrück, Biology, EM unit, Barbarastraße 11, 49076 Osnabrueck, Germany., Thielisch M; LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn, Carl-Troll-Strasse 31, 53115 Bonn, Germany., Sandhoff K; LIMES-Institute, Program Unit Membrane Biology & Lipid Biochemistry, c/o Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany., Hoch M; LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn, Carl-Troll-Strasse 31, 53115 Bonn, Germany m.hoch@uni-bonn.de sellin@uni-bonn.de.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2017 Jun 01; Vol. 10 (6), pp. 737-750. Date of Electronic Publication: 2017 Apr 07.

Neuroprotective role of coconut oil for the prevention and treatment of Parkinson's disease: potential mechanisms of action.

Autor: N. P, Deepika, Kondengadan, Mohammed Shameer, Sweilam, Sherouk Hussein, Rahman, Md. Habibur, Muhasina, K.M, Ghosh, Puja, Bhargavi, Divya, Palati, Divya Jyothi, Maiz, Fathi, Duraiswamy, B.

Publikováno v: Biotechnology & Genetic Engineering Reviews; Dec2024, Vol. 40 Issue 4, p3346-3378, 33p