Last but not least: emerging roles of the autophagy-related protein ATG4D.

Autor: McMann E; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada., Gorski SM; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.; Centre for Cell Biology, Development and Disease, Simon Fraser University, Burnaby, British Columbia, Canada.

Publikováno v: Autophagy [Autophagy] 2024 Sep; Vol. 20 (9), pp. 1916-1927. Date of Electronic Publication: 2024 Jul 08.

Unlocking the gate to GABARAPL2.

Autor: Chan JCY; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada.; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 1L3, Canada., Gorski SM; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada. sgorski@bcgsc.ca.; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 1L3, Canada. sgorski@bcgsc.ca.; Centre for Cell Biology, Development and Disease, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada. sgorski@bcgsc.ca.

Publikováno v: Biologia futura [Biol Futur] 2022 Jun; Vol. 73 (2), pp. 157-169. Date of Electronic Publication: 2022 Apr 29.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

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In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have als

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b957db3260a0aea6fcc371a74c1cf1f4

Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment.

Autor: Morimoto M; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Bhambhani V; Department of Medical Genetics, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, 55404, USA., Gazzaz N; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6H 3N1, Canada.; Provincial Medical Genetics Program, British Columbia Women's and Children's Hospital, Vancouver, BC, V6H 3N1, Canada.; Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Davids M; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Sathiyaseelan P; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada., Macnamara EF; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Lange J, Lehman A; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6H 3N1, Canada., Zerfas PM; Diagnostic and Research Services Branch, Office of Research Services, National Institutes of Health, Bethesda, MD, 20892, USA., Murphy JL; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Acosta MT; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Wang C; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA., Alderman E; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6H 3N1, Canada.; Provincial Medical Genetics Program, British Columbia Women's and Children's Hospital, Vancouver, BC, V6H 3N1, Canada., Reichert S; Department of Medical Genetics, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, 55404, USA., Thurm A; Neurodevelopmental and Behavioral Phenotyping Service, Office of the Clinical Director, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA., Adams DR; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA.; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Introne WJ; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA.; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Gorski SM; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6H 3N1, Canada.; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada., Boerkoel CF; Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6H 3N1, Canada.; Provincial Medical Genetics Program, British Columbia Women's and Children's Hospital, Vancouver, BC, V6H 3N1, Canada., Gahl WA; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA.; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Tifft CJ; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA.; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Malicdan MCV; National Institutes of Health Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health, Bethesda, MD, 20892, USA. maychristine.malicdan@nih.gov.; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. maychristine.malicdan@nih.gov.

Publikováno v: NPJ genomic medicine [NPJ Genom Med] 2023 Feb 10; Vol. 8 (1), pp. 4. Date of Electronic Publication: 2023 Feb 10.

Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations.

Autor: Xu J; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Yang KC; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Go NE; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Colborne S; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada., Ho CJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Hosseini-Beheshti E; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney NSW Australia., Lystad AH; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway., Simonsen A; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello, Norway., Guns ET; The Vancouver Prostate Centre, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Morin GB; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Gorski SM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Centre for Cell Biology, Development, and Disease, Simon Fraser University, Burnaby, BC, Canada.

Publikováno v: Autophagy [Autophagy] 2022 Nov; Vol. 18 (11), pp. 2547-2560. Date of Electronic Publication: 2022 Feb 28.