β-Amyloid disruption of LTP/LTD balance is mediated by AKAP150-anchored PKA and Calcineurin regulation of Ca ²⁺ -permeable AMPA receptors.

Autor: Sanderson JL; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA., Freund RK; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA., Gorski JA; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA., Dell'Acqua ML; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA; University of Colorado Alzheimer's and Cognition Center, Anschutz Medical Campus, Aurora, CO 80045, USA; Linda Crnic Institute for Down Syndrome, Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: mark.dellacqua@cuanschutz.edu.

Publikováno v: Cell reports [Cell Rep] 2021 Oct 05; Vol. 37 (1), pp. 109786.

Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca²⁺ channel may modulate its β-adrenergic regulation.

Autor: Oz, Shimrit^1,2 (AUTHOR), Keren-Raifman, Tal¹ (AUTHOR), Sharon, Tom¹ (AUTHOR), Subramaniam, Suraj³ (AUTHOR), Pallien, Tamara⁴ (AUTHOR), Katz, Moshe¹ (AUTHOR), Tsemakhovich, Vladimir¹ (AUTHOR), Sholokh, Anastasiia⁴ (AUTHOR), Watad, Baraa¹ (AUTHOR), Tripathy, Debi Ranjan^1,3,5 (AUTHOR), Sasson, Giorgia³ (AUTHOR), Chomsky-Hecht, Orna³ (AUTHOR), Vysochek, Leonid⁶ (AUTHOR), Schulz-Christian, Maike⁴ (AUTHOR), Fecher-Trost, Claudia⁷ (AUTHOR), Zühlke, Kerstin⁴ (AUTHOR), Bertinetti, Daniela⁸ (AUTHOR), Herberg, Friedrich W.⁸ (AUTHOR), Flockerzi, Veit⁷ (AUTHOR), Hirsch, Joel A.³ (AUTHOR)

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pyPAGE: A framework for Addressing biases in gene-set enrichment analysis—A case study on Alzheimer's disease.

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Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder.

Autor: Simões de Oliveira, Laura^1,2 (AUTHOR), O'Leary, Heather E.^3,4 (AUTHOR), Nawaz, Sarfaraz^1,2,5,6 (AUTHOR), Loureiro, Rita^1,2 (AUTHOR), Davenport, Elizabeth C.¹ (AUTHOR), Baxter, Paul^1,7 (AUTHOR), Louros, Susana R.^1,2 (AUTHOR), Dando, Owen^1,2,7 (AUTHOR), Perkins, Emma^1,2 (AUTHOR), Peltier, Julien⁸ (AUTHOR), Trost, Matthias⁸ (AUTHOR), Osterweil, Emily K.^1,2 (AUTHOR), Hardingham, Giles E.^1,2,7 (AUTHOR), Cousin, Michael A.^1,2,6 (AUTHOR), Chattarji, Sumantra^1,2,5,6 (AUTHOR), Booker, Sam A.^1,2 (AUTHOR), Benke, Tim A.^3,4 (AUTHOR) tim.benke@cuanschutz.edu, Wyllie, David J. A^1,2,6,9 (AUTHOR) david.j.a.wyllie@ed.ac.uk, Kind, Peter C.^1,2,6,9 (AUTHOR) p.kind@ed.ac.uk

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AKAP150-anchored PKA regulates synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the mouse lateral habenula.

Autor: Simmons, Sarah C.¹ (AUTHOR), Flerlage, William J.¹ (AUTHOR), Langlois, Ludovic D.¹ (AUTHOR), Shepard, Ryan D.¹ (AUTHOR), Bouslog, Christopher¹ (AUTHOR), Thomas, Emily H.¹ (AUTHOR), Gouty, Kaitlyn M.¹ (AUTHOR), Sanderson, Jennifer L.² (AUTHOR), Gouty, Shawn¹ (AUTHOR), Cox, Brian M.¹ (AUTHOR), Dell'Acqua, Mark L.² (AUTHOR) mark.dellacqua@cuanschutz.edu, Nugent, Fereshteh S.¹ (AUTHOR) fereshteh.nugent@usuhs.edu

Publikováno v: Communications Biology. 3/20/2024, Vol. 7 Issue 1, p1-14. 14p.