Polyoxometalate inhibition of SOX2-mediated tamoxifen resistance in breast cancer.

Autor: Aurrekoetxea-Rodriguez I; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Lee SY; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Rábano M; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Gris-Cárdenas I; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Gamboa-Aldecoa V; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Gorroño I; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Ramella-Gal I; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Parry C; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain., Kypta RM; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain.; Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK., Artetxe B; Department of Organic and Inorganic Chemistry, University of Basque Country UPV/EHU, Bilbao, 48080, Spain., Gutierrez-Zorrilla JM; Department of Organic and Inorganic Chemistry, University of Basque Country UPV/EHU, Bilbao, 48080, Spain., Vivanco MD; Cancer Heterogeneity Lab, CIC bioGUNE, BRTA, Technological Park Bizkaia, 801 A, Derio, Spain. mdmvivanco@cicbiogune.es.

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 02; Vol. 22 (1), pp. 425. Date of Electronic Publication: 2024 Sep 02.

Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis.

Autor: Stoletov K; Department of Oncology, University of Alberta, Edmonton, Alberta T6G 2E1, Canada., Sanchez S; Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain., Gorroño I; Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain., Rabano M; Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain., Vivanco MDM; Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain., Kypta R; Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain.; Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK., Lewis JD; Department of Oncology, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.

Publikováno v: Journal of cell science [J Cell Sci] 2023 Feb 01; Vol. 136 (3). Date of Electronic Publication: 2023 Feb 10.

The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.

Autor: Ormaza G; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Rodríguez JA; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Ibáñez de Opakua A; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Merino N; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Villate M; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Gorroño I; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Rábano M; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Palmero I; Instituto de Investigaciones Biomédicas 'Alberto Sols', CSIC-UAM, 28029 Madrid, Spain., Vilaseca M; Institute for Research in Biomedicine, 08028 Barcelona, Spain., Kypta R; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain; Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK., Vivanco MDM; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Rojas AL; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain., Blanco FJ; CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Spain; IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain. Electronic address: fblanco@cicbiogune.es.

Publikováno v: Journal of molecular biology [J Mol Biol] 2019 May 31; Vol. 431 (12), pp. 2298-2319. Date of Electronic Publication: 2019 Apr 24.

asteRIa enables robust interaction modeling between chromatin modifications and epigenetic readers.

Autor: Stadler, Mara, Lukauskas, Saulius, Bartke, Till, Müller, Christian L

Publikováno v: Nucleic Acids Research; 6/24/2024, Vol. 52 Issue 11, p6129-6144, 16p

ING5 inhibits aerobic glycolysis of lung cancer cells by promoting TIE1-mediated phosphorylation of pyruvate dehydrogenase kinase 1 at Y163.

Autor: Zhang H; Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China., Liu X; Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, 710038, China., Li J; Department of Oncology, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China., Meng J; Department of Pharmacy, the Medical Security Centre, Chinese PLA General Hospital, Beijing, 100091, China., Huang W; National Translational Science Center for Molecular Medicine and Department of Cell Biology, Fourth Military Medical University, Xi'an, 710038, China., Su X; Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China., Zhang X; Aerospace Clinical Medical Center, School of Aerospace Medicine, Fourth Military Medical University, Xi'an, 710038, China., Gao G; Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China., Wang X; Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China., Su H; Department of Oncology, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. suhc@fmmu.edu.cn., Zhang F; Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, 710038, China. zhangf037@163.com., Zhang T; Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. zhangft@fmmu.edu.cn.

Publikováno v: Frontiers of medicine [Front Med] 2024 Oct; Vol. 18 (5), pp. 878-895. Date of Electronic Publication: 2024 Sep 13.