Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma.

Autor: Berlow NE; Children's Cancer Therapy Development Institute, 12655 SW Beaverdam Road-West, Beaverton, OR, 97005, USA. noah@cc-tdi.org.; Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, 79409, USA. noah@cc-tdi.org., Rikhi R; Children's Cancer Therapy Development Institute, 12655 SW Beaverdam Road-West, Beaverton, OR, 97005, USA., Geltzeiler M; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; Department of Otolaryngology - Head and Neck Surgery, Oregon Health & Science University, Portland, OR, 97239, USA., Abraham J; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA., Svalina MN; Children's Cancer Therapy Development Institute, 12655 SW Beaverdam Road-West, Beaverton, OR, 97005, USA., Davis LE; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA., Wise E; Champions Oncology, Baltimore, MD, 21205, USA., Mancini M; Champions Oncology, Baltimore, MD, 21205, USA., Noujaim J; Royal Marsden Hospital and Institute of Cancer Research, London, SW3 6JJ, UK.; Hôpital Maisonneuve-Rosemont, Montreal, H1T 2M4, Canada., Mansoor A; Department of Pathology, Oregon Health & Science University, Portland, OR, 97239, USA., Quist MJ; Center for Spatial Systems Biomedicine Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, 97239, USA., Matlock KL; Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, 79409, USA.; Omics Data Automation, 12655 SW Beaverdam Road, Beaverton, OR 97005, USA., Goros MW; Department of Epidemiology and Biostatistics, University of Texas Health Science Center San Antonio, San Antonio, TX, 78229, USA., Hernandez BS; Department of Epidemiology and Biostatistics, University of Texas Health Science Center San Antonio, San Antonio, TX, 78229, USA., Doung YC; Department of Orthopedic Surgery, Oregon Health & Science University, Portland, OR, 97239, USA., Thway K; Royal Marsden Hospital and Institute of Cancer Research, London, SW3 6JJ, UK., Tsukahara T; Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, 060-8556, Japan., Nishio J; Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, 814-0180, Japan., Huang ET; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA., Airhart S; The Jackson Laboratory, Bar Harbor, ME, 04609, USA., Bult CJ; The Jackson Laboratory, Bar Harbor, ME, 04609, USA., Gandour-Edwards R; Department of Pathology & Laboratory Medicine, UC Davis Health System, Sacramento, CA, 95817, USA., Maki RG; Sarcoma Program, Zucker School of Medicine at Hofstra/Northwell & Cold Spring Harbor Laboratory, Long Island, NY, 10142, USA., Jones RL; Royal Marsden Hospital and Institute of Cancer Research, London, SW3 6JJ, UK., Michalek JE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center San Antonio, San Antonio, TX, 78229, USA., Milovancev M; Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR, 97331, USA., Ghosh S; Department of Mathematics and Statistics, Texas Tech University, Lubbock, TX, 79409, USA., Pal R; Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, 79409, USA. ranadip.pal@ttu.edu., Keller C; Children's Cancer Therapy Development Institute, 12655 SW Beaverdam Road-West, Beaverton, OR, 97005, USA. charles@cc-tdi.org.

Publikováno v: BMC cancer [BMC Cancer] 2019 Jun 17; Vol. 19 (1), pp. 593. Date of Electronic Publication: 2019 Jun 17.

The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma.

Autor: Bharathy N; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA., Berlow NE; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA., Wang E; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA., Abraham J; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA., Settelmeyer TP; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA., Hooper JE; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA., Svalina MN; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA., Ishikawa Y; Research Center, Shriners Hospital for Children, Portland, OR 97239, USA., Zientek K; Research Center, Shriners Hospital for Children, Portland, OR 97239, USA., Bajwa Z; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA.; Department of Pathology, Oregon Health & Science University, Portland, OR 97239, USA., Goros MW; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX 78229, USA., Hernandez BS; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX 78229, USA., Wolff JE; Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's, Cleveland, OH 44195, USA., Rudek MA; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21224, USA.; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA., Xu L; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21224, USA., Anders NM; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21224, USA., Pal R; Electrical and Computer Engineering, Texas Tech University, Lubbock, TX 79409, USA., Harrold AP; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA., Davies AM; Champions Oncology, Rockville, MD 20850, USA., Ashok A; Champions Oncology, Rockville, MD 20850, USA., Bushby D; Champions Oncology, Rockville, MD 20850, USA., Mancini M; Champions Oncology, Rockville, MD 20850, USA., Noakes C; Champions Oncology, Rockville, MD 20850, USA., Goodwin NC; Champions Oncology, Rockville, MD 20850, USA., Ordentlich P; Syndax Pharmaceuticals, Waltham, MA 02451, USA., Keck J; The Jackson Laboratory, Sacramento, CA 95838, USA., Hawkins DS; Seattle Children's Hospital, Seattle, WA 98105, USA., Rudzinski ER; Seattle Children's Hospital, Seattle, WA 98105, USA., Chatterjee B; Cancer Molecular Pathology Section, Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892-1500, USA., Bächinger HP; Research Center, Shriners Hospital for Children, Portland, OR 97239, USA.; Department of Biochemistry and Molecular Biology, Oregon Health & Science University, Portland, OR 97239, USA., Barr FG; Cancer Molecular Pathology Section, Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892-1500, USA., Liddle J; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA., Garcia BA; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA., Mansoor A; Department of Pathology, Oregon Health & Science University, Portland, OR 97239, USA., Perkins TJ; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa K1H 8L6, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa K1H 8M5, Canada., Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA., Michalek JE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX 78229, USA., Keller C; Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA. charles@cc-tdi.org.

Publikováno v: Science signaling [Sci Signal] 2018 Nov 20; Vol. 11 (557). Date of Electronic Publication: 2018 Nov 20.

Assisted hatching and live births in first-cycle frozen embryo transfers.

Autor: Knudtson JF; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas. Electronic address: knudtson@uthscsa.edu., Failor CM; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas., Gelfond JA; Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas., Goros MW; Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas., Chang TA; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas., Schenken RS; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas., Robinson RD; Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, Texas.

Publikováno v: Fertility and sterility [Fertil Steril] 2017 Oct; Vol. 108 (4), pp. 628-634. Date of Electronic Publication: 2017 Aug 30.

Drug Overdose: Differing Risk Models for Women and Men among Opioid Users with Non-Cancer Pain.

Autor: Liang Y; Department of Epidemiology and Biostatistics.; Center for Research to Advance Community Health (ReACH), University of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, Texas.; School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas., Goros MW; Department of Epidemiology and Biostatistics., Turner BJ; Center for Research to Advance Community Health (ReACH), University of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, Texas turner@uthscsa.edu.; School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas.; Department of Medicine, UTHSCSA. San Antonio, Texas, USA.

Publikováno v: Pain medicine (Malden, Mass.) [Pain Med] 2016 Dec; Vol. 17 (12), pp. 2268-2279. Date of Electronic Publication: 2016 Apr 28.

Lineage of origin in rhabdomyosarcoma informs pharmacological response.

Autor: Abraham J; Pediatric Cancer Biology Program, Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA;, Nuñez-Álvarez Y; Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Germans Trias i Pujol Health Sciences Research Institute (IGTP), 08916 Badalona, Barcelona, Spain;, Hettmer S; Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Joslin Diabetes Center, Cambridge, Massachusetts 02138, USA; Department of Pediatric Oncology, Dana Farber Cancer Institute, Division of Pediatric Hematology/Oncology, Children's Hospital, Boston, Massachusetts 02115, USA;, Carrió E; Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Germans Trias i Pujol Health Sciences Research Institute (IGTP), 08916 Badalona, Barcelona, Spain;, Chen HI; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Nishijo K; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Huang ET; Pediatric Cancer Biology Program, Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA;, Prajapati SI; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Walker RL; Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877, USA;, Davis S; Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877, USA;, Rebeles J; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Wiebush H; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, McCleish AT; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Hampton ST; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Bjornson CR; Department of Neurology, Department of Neurological Sciences, Glenn Laboratories for the Biology of Aging, Stanford University, Palo Alto, California 94304, USA;, Brack AS; Department of Neurology, Department of Neurological Sciences, Glenn Laboratories for the Biology of Aging, Stanford University, Palo Alto, California 94304, USA;, Wagers AJ; Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Joslin Diabetes Center, Cambridge, Massachusetts 02138, USA;, Rando TA; Department of Neurology, Department of Neurological Sciences, Glenn Laboratories for the Biology of Aging, Stanford University, Palo Alto, California 94304, USA;, Capecchi MR; Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA;, Marini FC; Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA;, Ehler BR; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Zarzabal LA; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Goros MW; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Michalek JE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Meltzer PS; Oncogenomics Section, Pediatric Oncology Branch, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877, USA;, Langenau DM; Department of Pathology, Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA;, LeGallo RD; Department of Pathology, University of Virginia, Charlottesville, Virginia 22903, USA;, Mansoor A; Department of Pathology, Oregon Health and Science University, Portland, Oregon 97239, USA;, Chen Y; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas 78229, USA;, Suelves M; Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Germans Trias i Pujol Health Sciences Research Institute (IGTP), 08916 Badalona, Barcelona, Spain;, Rubin BP; Department of Anatomic Pathology, Department of Molecular Genetics, Taussig Cancer Center, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA., Keller C; Pediatric Cancer Biology Program, Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA;

Publikováno v: Genes & development [Genes Dev] 2014 Jul 15; Vol. 28 (14), pp. 1578-91.