An improved pathway for autonomous bioluminescence imaging in eukaryotes.

Autor: Shakhova ES; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Karataeva TA; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Markina NM; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Mitiouchkina T; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Palkina KA; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Perfilov MM; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Wood MG; Promega Corporation, Madison, WI, USA., Hoang TT; Promega Corporation, Madison, WI, USA., Hall MP; Promega Corporation, Madison, WI, USA., Fakhranurova LI; Planta LLC, Moscow, Russia., Alekberova AE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Malyshevskaia AK; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Gorbachev DA; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Bugaeva EN; Planta LLC, Moscow, Russia., Pletneva LK; Planta LLC, Moscow, Russia., Babenko VV; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia., Boldyreva DI; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia., Gorokhovatsky AY; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Balakireva AV; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Gao F; Synthetic Biology Group, MRC Laboratory of Medical Sciences, London, UK.; Institute of Clinical Sciences, Faculty of Medicine and Imperial College Centre for Synthetic Biology, Imperial College London, London, UK., Choob VV; Planta LLC, Moscow, Russia.; Botanical Garden of Lomonosov Moscow State University, Moscow, Russia., Encell LP; Promega Corporation, Madison, WI, USA., Wood KV; Light Bio Inc, Ketchum, ID, USA., Yampolsky IV; Planta LLC, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; Light Bio Inc, Ketchum, ID, USA.; Pirogov Russian National Research Medical University, Moscow, Russia., Sarkisyan KS; Planta LLC, Moscow, Russia. karen@light.bio.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. karen@light.bio.; Synthetic Biology Group, MRC Laboratory of Medical Sciences, London, UK. karen@light.bio.; Institute of Clinical Sciences, Faculty of Medicine and Imperial College Centre for Synthetic Biology, Imperial College London, London, UK. karen@light.bio.; Light Bio Inc, Ketchum, ID, USA. karen@light.bio., Mishin AS; Planta LLC, Moscow, Russia. alexander@planta.bio.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. alexander@planta.bio.

Publikováno v: Nature methods [Nat Methods] 2024 Mar; Vol. 21 (3), pp. 406-410. Date of Electronic Publication: 2024 Jan 22.

Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives.

Autor: Kostyuk AI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117997, Moscow, Russia.; Laboratory of Experimental Oncology, Pirogov Russian National Research Medical University, 117997, Moscow, Russia., Tossounian MA; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, B-1050, Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050, Brussels, Belgium.; Department of Structural and Molecular Biology, University College London, London, WC1E 6BT, United Kingdom., Panova AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117997, Moscow, Russia.; Laboratory of Experimental Oncology, Pirogov Russian National Research Medical University, 117997, Moscow, Russia., Thauvin M; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, PSL Research University, Paris, 75231, France.; Sorbonne Université, Collège Doctoral, Paris, 75005, France., Raevskii RI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia., Ezeriņa D; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, B-1050, Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050, Brussels, Belgium., Wahni K; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, B-1050, Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050, Brussels, Belgium., Van Molle I; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, B-1050, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050, Brussels, Belgium., Sergeeva AD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia.; Biological Department, Lomonosov Moscow State University, 119992, Moscow, Russia., Vertommen D; de Duve Institute, MASSPROT platform, UCLouvain, 1200, Brussels, Belgium., Gorokhovatsky AY; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia., Baranov MS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia.; Laboratory of Medicinal Substances Chemistry, Pirogov Russian National Research Medical University, 117997, Moscow, Russia., Vriz S; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, PSL Research University, Paris, 75231, France.; Université de Paris, Paris, 75006, France.; Laboratoire des biomolécules, LBM, Département de chimie, École normale supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France., Messens J; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, B-1050, Brussels, Belgium. joris.messens@vub.be.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050, Brussels, Belgium. joris.messens@vub.be.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050, Brussels, Belgium. joris.messens@vub.be., Bilan DS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia. d.s.bilan@gmail.com.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117997, Moscow, Russia. d.s.bilan@gmail.com.; Laboratory of Experimental Oncology, Pirogov Russian National Research Medical University, 117997, Moscow, Russia. d.s.bilan@gmail.com., Belousov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997, Moscow, Russia. belousov@fccps.ru.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117997, Moscow, Russia. belousov@fccps.ru.; Laboratory of Experimental Oncology, Pirogov Russian National Research Medical University, 117997, Moscow, Russia. belousov@fccps.ru.; Federal Center of Brain Research and Neurotechnologies, Federal Medical Biological Agency, 117997, Moscow, Russia. belousov@fccps.ru.

Publikováno v: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 171. Date of Electronic Publication: 2022 Jan 10.

Genetically encodable bioluminescent system from fungi.

Autor: Kotlobay AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Sarkisyan KS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia; karen@planta.bio ivyamp@gmail.com.; Planta LLC, 121205 Moscow, Russia.; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria.; Medical Research Council London Institute of Medical Sciences, Imperial College London, W12 0NN London, United Kingdom., Mokrushina YA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Marcet-Houben M; Centre for Genomic Regulation, The Barcelona Institute for Science and Technology, 08003 Barcelona, Spain.; Universitat Pompeu Fabra, 08003 Barcelona, Spain., Serebrovskaya EO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Markina NM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Planta LLC, 121205 Moscow, Russia.; Evrogen JSC, 117997 Moscow, Russia., Gonzalez Somermeyer L; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria., Gorokhovatsky AY; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Vvedensky A; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Purtov KV; Institute of Biophysics, Federal Research Center Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, 660036 Krasnoyarsk, Russia., Petushkov VN; Institute of Biophysics, Federal Research Center Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, 660036 Krasnoyarsk, Russia., Rodionova NS; Institute of Biophysics, Federal Research Center Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, 660036 Krasnoyarsk, Russia., Chepurnyh TV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Fakhranurova LI; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Moscow, Russia., Guglya EB; Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Ziganshin R; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Tsarkova AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Kaskova ZM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Shender V; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Abakumov M; Pirogov Russian National Research Medical University, 117997 Moscow, Russia.; Biomedical Nanomaterials, National Research Technological University (MISiS), 119049 Moscow, Russia., Abakumova TO; Skolkovo Institute of Science and Technology, 121205 Moscow, Russia., Povolotskaya IS; Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Eroshkin FM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Zaraisky AG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Mishin AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Dolgov SV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Mitiouchkina TY; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Planta LLC, 121205 Moscow, Russia., Kopantzev EP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Waldenmaier HE; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, 05508-000 São Paulo, Brazil., Oliveira AG; Departamento de Oceanografia Física, Química e Geológica, Instituto Oceanográfico, Universidade de São Paulo, 05508-120 São Paulo, Brazil., Oba Y; Department of Environmental Biology, Chubu University, 487-8501 Kasugai, Japan., Barsova E; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Evrogen JSC, 117997 Moscow, Russia., Bogdanova EA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Gabaldón T; Centre for Genomic Regulation, The Barcelona Institute for Science and Technology, 08003 Barcelona, Spain.; Universitat Pompeu Fabra, 08003 Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), 08010 Barcelona, Spain., Stevani CV; Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, 05508-000 São Paulo, Brazil., Lukyanov S; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Smirnov IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Gitelson JI; Institute of Biophysics, Federal Research Center Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, 660036 Krasnoyarsk, Russia., Kondrashov FA; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria., Yampolsky IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia; karen@planta.bio ivyamp@gmail.com.; Planta LLC, 121205 Moscow, Russia.; Pirogov Russian National Research Medical University, 117997 Moscow, Russia.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Dec 11; Vol. 115 (50), pp. 12728-12732. Date of Electronic Publication: 2018 Nov 26.

Structure of fungal oxyluciferin, the product of the bioluminescence reaction.

Autor: Purtov KV; Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia. purtovk@mail.ru., Osipova ZM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia., Petushkov VN; Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia., Rodionova NS; Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia., Tsarkova AS; Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia., Kotlobay AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia., Chepurnykh TV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia., Gorokhovatsky AY; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia., Yampolsky IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia., Gitelson JI; Krasnoyarsk Science Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russia.

Publikováno v: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2017 Nov; Vol. 477 (1), pp. 360-363. Date of Electronic Publication: 2018 Jan 03.

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