Validation of high-performance liquid chromatography–tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4′‑des-methyl and cephalotaxine metabolites in human plasma and urine

Autor: Nijenhuis, C. M., Lucas, L., Rosing, H., Schellens, J. H M, Beijnen, J. H., Gorman, S. H., Burke, S. M., Campbell, D. A., Chapple, M. W., Yousey, T. H., Mulvana, D. E., Pharmacoepidemiology and Clinical Pharmacology, Sub Clinical Pharmacology

Publikováno v: Journal of chromatography. B, 1002, 152. Elsevier

Omacetaxine mepesuccinate (hereafter called omacetaxine) is a modified cephalotaxine and is registered (Synribo®) for the treatment of adult patients with chronic myeloid leukemia (CML) with resistance and/or intolerance to two or more tyrosine kina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19d5580ad46cf60b11014615153e687
https://doi.org/10.1016/j.jchromb.2015.08.015

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Corrigendum to "Development and validation of LC-MS/MS assays for the quantification of bendamustine and its metabolites in human plasma and urine" [J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 893-894 (2012) 92-100].

Autor: Dubbelman AC; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands. Electronic address: a.c.dubbelman@lacdr.leidenuniv.nl., Tibben M; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands., Rosing H; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands., Gebretensae A; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands., Nan L; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands., Gorman SH; Department of Global Nonclinical DMPK, Teva Pharmaceutical Industries Ltd., 145 Brandywine Parkway, West Chester, PA 19380, United States., Robertson P Jr; Department of Global Nonclinical DMPK, Teva Pharmaceutical Industries Ltd., 145 Brandywine Parkway, West Chester, PA 19380, United States., Schellens JH; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands; Science Faculty, Department of Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584CA Utrecht, The Netherlands., Beijnen JH; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands; Science Faculty, Department of Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584CA Utrecht, The Netherlands.

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2016 May 01; Vol. 1020, pp. 168-9. Date of Electronic Publication: 2016 Mar 25.