Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gorjana Lazarevski"'
Publikováno v:
ADMET and DMPK, Vol 2, Iss 3, Pp 179-184 (2014)
Electrochemical synthesis, structure elucidation and antibacterial evaluation of 9a-aza-9a-chloro-9a-homoerythromycin A were carried out. It was found that the anodic oxidation of 9a-aza-9a-homoerythromycin A via electrogenerated reactive chlorine sp
Externí odkaz:
https://doaj.org/article/1ca4c1fbdd8840deb0a99deffcda697e
Autor:
Mark B Vine, Martina Bosnar, Goran Kragol, Ivanka Pašalić, Ognjen Čulić, Gorjana Lazarevski, Jurica Bauer, Ilija Čorić, Gordana Turkalj
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:2274-2281
A set of 8-methylene-, 8-methyl-, and 8-methyl- 9-dihydro-oleandomycin derivatives having different combinations of stereochemistries at positions C-8 and/or C-9 have been prepared in a chemoselective and stereoselective manner and tested in vitro fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66f80a4560d3043a4c0201be2e6bb31
https://doi.org/10.1016/j.bmc.2012.02.013
https://doi.org/10.1016/j.bmc.2012.02.013
Autor:
Dubravka Matković-Čalogović, Zorica Marušić Ištuk, Dubravka Gembarovski, Gorjana Lazarevski, Goran Kragol, Ivica Đilović, Ana Čikoš
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:556-566
An efficient one-pot method for the synthesis of novel 9a, 11-bridged 15-membered 9a-aza-9-deoxo-9ahomoerythromycin A and its 6-O-methyl analogue has been developed. The novel bicyclic azalide scaffold is characterized by an N'-substituted-2-imino-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202dbd8f2cd3831c3c157bfbc44f85d5
https://doi.org/10.1016/j.bmc.2010.10.061
https://doi.org/10.1016/j.bmc.2010.10.061
Autor:
Stjepan Mutak, Miljenko Dumić, V. Sunjic, Antun Hutinec, Sulejman Alihodžić, Vesna Eraković Haber, Nataša Maršić, Gorjana Lazarevski, Marko Đerek, Hana Čipčić Paljetak
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3244-3249
Fifteen-membered 8a-aza-8a-homoerythromycins derived from either erythromycin or clarithromycin have been acylated to form 4″-O-propenoyl derivative. These functionalized analogues underwent Michael reaction with primary or secondary amines to affo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e143e8a7738cbf990c57b8c1d97c5f2
https://doi.org/10.1016/j.bmcl.2010.04.062
https://doi.org/10.1016/j.bmcl.2010.04.062
Autor:
Vlado, Stimac, Sulejman, Alihodzic, Gorjana, Lazarevski, Stjepan, Mutak, Zorica Marusic, Istuk, Andrea, Fajdetic, Ivana, Palej, Hana Cipcic, Paljetak, Natasa, Marsic, Jasna, Padovan, Branka, Tavcar, Vesna, Erakovic Haber
Publikováno v:
The Journal of Antibiotics. 62:133-144
A series of 4”-O-acyl derivatives of 8a-aza-8a- homoerythromycins A were synthesised and tested against Gram-positive and Gram-negative bacteria. Derivatives of 8a-aza-8a-homoerythromycin A have potent antibacterial activity against not only azithr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51113c036dc29314f400fbf30307462
https://doi.org/10.1038/ja.2009.1
https://doi.org/10.1038/ja.2009.1
Autor:
Stjepan Mutak, Hana Cipcic, Gabrijela Kobrehel, Vlado Štimac, Wolfgang Schoenfeld, Andrea Fajdetić, Miroslava Dominis Kramaric, Andreja Hasenöhrl, Vesna Eraković, Dražen Pavlović, Sulejman Alihodzic, Nataša Maršić, Gorjana Lazarevski
Publikováno v:
The Journal of Antibiotics. 59:753-769
A series of 3-keto and 3-O-acyl derivatives of both 6-O-alkyl-8a-aza-8a-homoerythromycin A and 6- O-alkyl-9a-aza-9a-homo-erythromycin A were synthesised and tested against gram-positive and gram-negative bacteria. Derivatives of 8a-aza-8a- homoerythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d7ffa0b4ff22db6c05cb53dce27a6c
https://doi.org/10.1038/ja.2006.100
https://doi.org/10.1038/ja.2006.100
Autor:
Predrag Novak, Predrag Tepeš, Zrinka Banić Tomišić, Gorjana Lazarevski, Gordana Turkalj, Janez Plavec
Publikováno v:
Org. Biomol. Chem.. 3:39-47
Conformations of the 14-membered macrolide antibiotic oleandomycin and its 8-methylene-9-oxime derivative were determined in various solvents. The experimental NMR data--coupling constants and NOE contacts--were compared with the results of molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decc57bd508c0694b602255912695512
https://doi.org/10.1039/b412294a
https://doi.org/10.1039/b412294a
Publikováno v:
ADMET and DMPK
Volume 2
Issue 3
ADMET and DMPK, Vol 2, Iss 3, Pp 179-184 (2014)
Volume 2
Issue 3
ADMET and DMPK, Vol 2, Iss 3, Pp 179-184 (2014)
Electrochemical synthesis, structure elucidation and antibacterial evaluation of 9a-aza-9a-chloro-9a-homoerythromycin A were carried out. It was found that the anodic oxidation of 9a-aza-9a-homoerythromycin A via electrogenerated reactive chlorine sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c592d25db5f6674ddcdb049fb78432
https://hrcak.srce.hr/127041
https://hrcak.srce.hr/127041
Publikováno v:
The Journal of Antibiotics. 49:1066-1069
Ring opening reactions of 6-deoxy-9-deoxo-9a-aza-9a- homoerythromycin A 6, 9-cyclic imino ether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b960d231c80c47ed17d6539aaa091
https://doi.org/10.7164/antibiotics.49.1066
https://doi.org/10.7164/antibiotics.49.1066
Publikováno v:
Zeitschrift für Kristallographie - Crystalline Materials. 210:516-520
The crystal structure of the title compound, C35H62N2O11 · 2H2O, has been determined at room temperature by X-ray diffraction. The colorless crystals are monoclinic, space group C2, with unit cell dimensions a = 16.407(8) Å, b = 11.679(6) Å, c = 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113ca06dceda0560fca068a09d26d475
https://doi.org/10.1524/zkri.1995.210.7.516
https://doi.org/10.1524/zkri.1995.210.7.516