Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)

Autor: Goren Saenz-Pipaon, Patxi San Martín, Núria Planell, Alberto Maillo, Susana Ravassa, Amaia Vilas-Zornoza, Esther Martinez-Aguilar, José Antonio Rodriguez, Daniel Alameda, David Lara-Astiaso, Felipe Prosper, José Antonio Paramo, Josune Orbe, David Gomez-Cabrero, Carmen Roncal

Publikováno v: Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)

Peripheral arterial disease (PAD) is associated with a high risk of cardiovascular events and death and is postulated to be a critical socioeconomic cost in the future. Extracellular vesicles (EVs) have emerged as potential candidates for new biomark

Externí odkaz: https://doaj.org/article/2571a4225cb14860afdd7c2eb331c1f5

Lipocalin-2 and Calprotectin Potential Prognosis Biomarkers in Peripheral Arterial Disease

Autor: Goren Saenz-Pipaon, Susana Ravassa, Katrine L. Larsen, Esther Martinez-Aguilar, Josune Orbe, Jose A. Rodriguez, Leopoldo Fernandez-Alonso, Arantxa Gonzalez, Jose L. Martín-Ventura, Jose A. Paramo, Jes S. Lindholt, Carmen Roncal

Publikováno v: Saenz-Pipaon, G, Ravassa, S, Larsen, K L, Martinez-Aguilar, E, Orbe, J, Rodriguez, J A, Fernandez-Alonso, L, Gonzalez, A, Martín-Ventura, J L, Paramo, J A, Lindholt, J S & Roncal, C 2022, ' Lipocalin-2 and Calprotectin Potential Prognosis Biomarkers in Peripheral Arterial Disease ', European Journal of Vascular and Endovascular Surgery, vol. 63, no. 4, pp. 648-656 . https://doi.org/10.1016/j.ejvs.2022.01.012

Objective: Peripheral arterial disease (PAD) is the most prevalent cardiovascular (CV) condition globally. Despite the high CV risk of PAD patients, no reliable predictors of adverse clinical evolution are yet available. In this regard, previous tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6f2587b940ce5753d1fb72225fb9ab
https://pubmed.ncbi.nlm.nih.gov/35307155

Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)

Autor: Carmen Roncal, Josune Orbe, Amaia Vilas-Zornoza, Núria Planell, David Lara-Astiaso, Felipe Prosper, Esther Martinez-Aguilar, Goren Saenz-Pipaon, Alberto Maillo, David Gomez-Cabrero, Patxi San Martin, Daniel Alameda, Susana Ravassa, José A. Páramo, José Antonio Rodriguez

Publikováno v: Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Journal of Extracellular Vesicles

Peripheral arterial disease (PAD) is associated with a high risk of cardiovascular events and death and is postulated to be a critical socioeconomic cost in the future. Extracellular vesicles (EVs) have emerged as potential candidates for new biomark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735d5de0ab4a6154b1bb24b0952ac44f
https://hdl.handle.net/10171/66300

Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

Autor: Sebastián Fernández-Alonso, Josune Orbe, José A. Páramo, Esther Martinez-Aguilar, Susana Ravassa, Alejandro Fernández-Montero, Jose A. Rodriguez, Ander Estella-Hermoso de Mendoza, Ana Ugarte, Julen Oyarzabal, Carmen Roncal, Goren Saenz-Pipaon, Leopoldo Fernández-Alonso

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

Peripheral artery disease (PAD) is a major cause of acute and chronic illness, with extremely poor prognosis that remains underdiagnosed and undertreated. Trimethylamine-N-Oxide (TMAO), a gut derived metabolite, has been associated with atherosclerot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c5037d65cd60a7c8968dc92af22004
https://pubmed.ncbi.nlm.nih.gov/31666590

The Role of Circulating Biomarkers in Peripheral Arterial Disease

Autor: Esther Martinez-Aguilar, José A. Páramo, Leopoldo Fernández-Alonso, Carmen Roncal, Goren Saenz-Pipaon, Arantxa González Miqueo, Josune Orbe

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 3601, p 3601 (2021)
International Journal of Molecular Sciences

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is one of the most prevalent CV conditions worldwide in subject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d641176687e594a29580170a6f211e4
https://doi.org/10.3390/ijms22073601