Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Gordon Y C, Cheung"'
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 130 (2024)
Staphylococcus pseudintermedius is a frequent cause of infections in dogs. Infectious isolates of this coagulase-positive staphylococcal species are often methicillin- and multidrug-resistant, which complicates therapy. In staphylococci, methicillin
Externí odkaz:
https://doaj.org/article/fb9bd3d64e2f42469e04b87a69e4228f
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 547-569 (2021)
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and mortality due to an infectious agent. This pathogen can cause a wide variety of diseases, ranging from moderately severe skin infections to fatal pneumonia and sepsis
Externí odkaz:
https://doaj.org/article/69c7f1cacc214f9cb677b9c9f31ebdec
Autor:
Kunal Reshamwala, Gordon Y. C. Cheung, Roger C. Hsieh, Ryan Liu, Hwang-Soo Joo, Yue Zheng, Justin S. Bae, Thuan H. Nguyen, Amer E. Villaruz, Alfonso S. Gozalo, William R. Elkins, Michael Otto
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In contrast to the virulent human skin commensal Staphylococcus aureus, which secretes a plethora of toxins, other staphylococci have much reduced virulence. In these species, commonly the only toxins are those of the phenol-soluble modulin (PSM) fam
Externí odkaz:
https://doaj.org/article/1ab25afc56a24339b5e2705178dfccee
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009369 (2021)
Bacterial sepsis is a major global cause of death. However, the pathophysiology of sepsis has remained poorly understood. In industrialized nations, Staphylococcus aureus represents the pathogen most commonly associated with mortality due to sepsis.
Externí odkaz:
https://doaj.org/article/33194c3e73384549a0562a5760ba9397
Autor:
Ping Miao, Yiming Jiang, Ying Jian, Jiali Shi, Yao Liu, Pipat Piewngam, Yue Zheng, Gordon Y. C. Cheung, Qian Liu, Michael Otto, Min Li
Publikováno v:
Nature Microbiology. 8:218-230
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that share structural and functional similarities and possess potent superantigenic activity causing disruptions in adaptive immunity. The enterotoxins can be sepa
Externí odkaz:
https://doaj.org/article/1ead4cde35a84f129dec12d1459fcffd
Autor:
Fei Da, Hwang-Soo Joo, Gordon Y. C. Cheung, Amer E. Villaruz, Holger Rohde, Xiaoxing Luo, Michael Otto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Coagulase-negative staphylococci (CoNS) are important nosocomial pathogens and the leading cause of sepsis. The second most frequently implicated species, after Staphylococcus epidermidis, is Staphylococcus haemolyticus. However, we have a significan
Externí odkaz:
https://doaj.org/article/21bfc1629fa242c88bf0174aed078fb5
Autor:
Li Qin, Fei Da, Emilie L Fisher, Daniel C S Tan, Thuan H Nguyen, Chih-Lung Fu, Vee Y Tan, Joshua W McCausland, Daniel E Sturdevant, Hwang-Soo Joo, Shu Y Queck, Gordon Y C Cheung, Michael Otto
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006153 (2017)
Bacterial sepsis is a major killer in hospitalized patients. Coagulase-negative staphylococci (CNS) with the leading species Staphylococcus epidermidis are the most frequent causes of nosocomial sepsis, with most infectious isolates being methicillin
Externí odkaz:
https://doaj.org/article/0232038b1b1e4dd497951e084a965e80
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 547-569 (2021)
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and mortality due to an infectious agent. This pathogen can cause a wide variety of diseases, ranging from moderately severe skin infections to fatal pneumonia and sepsis
Autor:
Gordon Y. C. Cheung, Michael Otto, Justin S. Bae, Lei He, Govindarajan Rajagopalan, Huiying Lv, Emilie L. Fisher, Min Li, Ryan Liu, Fei Da
Publikováno v:
J Infect Dis
Staphylococcal enterotoxin B (SEB), which is produced by the major human pathogen, Staphylococcus aureus, represents a powerful superantigenic toxin and is considered a bioweapon. However, the contribution of SEB to S. aureus pathogenesis has never b