Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Gordon W. Arbuthnott"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 15, Iss , Pp 21-25 (2017)
We present three reasons to suspect that the major deleterious consequence of dopamine loss from the striatum is a cortical malfunction. We suggest that it is cortex, rather than striatum, that should be considered as the source of the debilitating s
Externí odkaz:
https://doaj.org/article/442d7adc3baf41f5b69e1d5e6ceeae25
Autor:
Gordon W. Arbuthnott
Publikováno v:
Cells, Vol 10, Iss 3, p 513 (2021)
I feel part of a massive effort to understand what is wrong with motor systems in the brain relating to Parkinson’s disease. Today, the symptoms of the disease can be modified slightly, but dopamine neurons still die; the disease progression contin
Externí odkaz:
https://doaj.org/article/5de6973002e94539b30584e4deca4644
Publikováno v:
Frontiers in Neuroanatomy, Vol 4 (2010)
The most appealing models of how the basal ganglia function, propose distributed patterns of cortical activity selectively interacting with striatal networks to yield the execution of context-dependent movements. If movement is encoded by patterns of
Externí odkaz:
https://doaj.org/article/b2e2a388e5f7457898d6cc615bd572f5
Autor:
Bianca Sieveritz, Gordon W. Arbuthnott
Publikováno v:
Brain Structure & Function
Ventromedial thalamic axons innervate cortical layer I and make contacts onto the apical dendritic tuft of pyramidal neurons. Optical stimulation of ventromedial thalamic axon terminals in prefrontal cortical areas in mouse brain slices evokes respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0feefaf6e4f8c1ff851042950bf02f
http://europepmc.org/articles/PMC7473973
http://europepmc.org/articles/PMC7473973
Corticostriatal neurons in prelimbic cortex contribute to decisions that require a trade-off between cost and benefit. The ventral motor thalamus sends dense projections to many cortical areas, including the prelimbic cortex. We investigated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ae35e26c1cd734c02ae657faf2077b
https://doi.org/10.1101/2022.02.11.480170
https://doi.org/10.1101/2022.02.11.480170
Autor:
Diana L, Rodriguez-Munoz, Omar, Jaidar, Marcela, Palomero-Rivero, Mario A, Arias-Garcia, Gordon W, Arbuthnott, Violeta G, Lopez-Huerta
Publikováno v:
Journal of visualized experiments : JoVE. (177)
Fine motor skills are essential in everyday life and can be compromised in several nervous system disorders. The acquisition and performance of these tasks require sensory-motor integration and involve precise control of bilateral brain circuits. Imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::874b69af7393641a048c9241fe799df4
https://pubmed.ncbi.nlm.nih.gov/34866625
https://pubmed.ncbi.nlm.nih.gov/34866625
Autor:
Marianela Garcia-Munoz, Luis Carrillo-Reid, José Bargas, Gordon W. Arbuthnott, Arturo Hernández-Cruz, Yoko Nakano, Violeta G. Lopez-Huerta, Omar Jáidar
Publikováno v:
The European Journal of Neuroscience
For more than three decades it has been known, that striatal neurons become hyperactive after the loss of dopamine input, but the involvement of dopamine (DA) D1‐ or D2‐receptor‐expressing neurons has only been demonstrated indirectly. By recor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65de7687af89d6259f18b10fd3af616
http://id.nii.ac.jp/1394/00000993/
http://id.nii.ac.jp/1394/00000993/
Publikováno v:
The European Journal of Neuroscience
The focus of this literature review is on the three interacting brain areas that participate in decision‐making: basal ganglia, ventral motor thalamic nuclei, and medial prefrontal cortex, with an emphasis on the participation of the ventromedial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e8c2e1608657338c7dfd95568de1fa
https://doi.org/10.1111/ejn.14215
https://doi.org/10.1111/ejn.14215
Publikováno v:
The European Journal of Neuroscience
The purpose of this review is to bridge the gap between earlier literature on striatal cholinergic interneurons and mechanisms of microcircuit interaction demonstrated with the use of newly available tools. It is well known that the main source of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecd832db8aada319986b303efecadb6
http://europepmc.org/articles/PMC6587740
http://europepmc.org/articles/PMC6587740
Autor:
Fiona E Randall, Marianela eGarcia-Munoz, Catherine eVickers, Sarah C Schock, William A Staines, Gordon W Arbuthnott
Publikováno v:
Frontiers in Systems Neuroscience, Vol 5 (2011)
The sparse connectivity within the striatum in vivo makes the investigation of individual corticostriatal synapses very difficult. Most studies of the corticostriatal input have been done using electrical stimulation under conditions under which it i
Externí odkaz:
https://doaj.org/article/8dc83d07f3b6423181fb2ce423006a03