Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gordon R. Sandford"'
Publikováno v:
Journal of Virology. 91
The contributions of human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) to virus biology remain unclear. Here we examined the role of vIL-6/gp130 signaling in HHV-8 productive replication in primary effusion lymphoma and endothelial cells. Deple
Publikováno v:
Journal of Virology. 88:12167-12172
The contributions of human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) to virus biology remain unclear. Here we examined the role of vIL-6/gp130 signaling in HHV-8 productive replication in primary effusion lymphoma and endothelial cells. Deple
Publikováno v:
Journal of Virology. 83:13009-13014
The human herpesvirus 8 (HHV-8) viral G protein-coupled receptor (vGPCR) has been implicated in virus-associated disease pathogenesis due principally to its ability to induce the production of angiogenic cytokines involved in this process. However, t
Autor:
Uwe Schumacher, Sebastian Voigt, Gordon R. Sandford, Gary S. Hayward, Jakob Ettinger, William H. Burns, Wolfram Brune
Publikováno v:
Journal of General Virology. 91:616-621
The immediate-early 1 (IE1) and IE2 proteins encoded by the major immediate-early (MIE) transcription unit of cytomegaloviruses are thought to play key roles in the switch between latent- and lytic-cycle infection. Whilst IE2 is essential for trigger
Publikováno v:
Journal of Virology. 83:6874-6882
Human herpesvirus 8 (HHV-8) interleukin-6 (vIL-6) is distinct from human and other cellular IL-6 proteins in that it does not require the nonsignaling α-receptor subunit for the formation of gp130-based signal transducing complexes and also is large
Autor:
Henriette Geyer, Lars Möller, Andreas Nitsche, Sarah Y. Heaggans, Gary S. Hayward, Wolfram Brune, Sebastian Voigt, Erik Schmolz, Gordon R. Sandford, Jakob Ettinger
Publikováno v:
The Journal of general virology. 96(Pt 7)
The genome of the rat cytomegalovirus (RCMV) English isolate (MuHV-8) differs significantly from the RCMV Maastricht isolate (MuHV-2) and other cytomegaloviruses (CMVs) in its size, base composition and genomic content. Analysis of the RCMV-Berlin is
Autor:
Kimberly A. Gerber, Rimas J. Orentas, Gordon R. Sandford, Edit Olasz, Marja C. Konkol, Robert L. Truitt, Michael Rosenblum, Jeffery E. Woodliff, Bryon D. Johnson
Publikováno v:
Blood. 103:2691-2698
During apoptotic cell death, biochemical processes modify self-proteins and create potential autoantigens. To maintain self-tolerance in the face of natural cell turnover, the immune system must prevent or control responses to apoptosis-associated au
Autor:
David A. Margolis, William H. Burns, Carla Lawendowski, Carolyn A. Keever-Taylor, Steve Konings, Charles A Nicolette, Gordon R. Sandford
Publikováno v:
Biology of Blood and Marrow Transplantation. 7(5):247-256
Cytomegalovirus (CMV) infection is a serious complication of allogeneic bone marrow transplantation (BMT). CMV disease can usually be prevented by passive immunization with donor-derived CMV-pp65-specific T-cell clones if provided early post-BMT. The
Publikováno v:
Blood. 97:2506-2513
Donor T cells play a pivotal role in facilitating alloengraftment but also cause graft-versus-host disease (GVHD). Ex vivo T-cell depletion (TCD) of donor marrow is the most effective strategy for reducing GVHD but can compromise engraftment. This st
Autor:
Kazuyo Takeda, Stephen E. Epstein, Gordon R. Sandford, Koichi Tanaka, Victor J. Ferrans, Toren Finkel, Thomas M. Johnson, Jian Ping Zou
Publikováno v:
Circulation. 99:1656-1659
Background —Restenotic and atherosclerotic lesions often contain smooth muscle cells (SMCs), which display high rates of proliferation and apoptosis. Human cytomegalovirus (HCMV) may increase the incidence of restenosis and predispose to atheroscle