Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gordon M, Keller"'
Autor:
Gregory M. Kent, Michael H. Atkins, Bryan Lung, Adele Nikitina, Ian M. Fernandes, Jamie J. Kwan, Tallulah S. Andrews, Sonya A. MacParland, Gordon M. Keller, Blair K. Gage
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114629- (2024)
Summary: In mice, the first liver-resident macrophages, known as Kupffer cells (KCs), are thought to derive from yolk sac (YS) hematopoietic progenitors that are specified prior to the emergence of the hematopoietic stem cell (HSC). To investigate hu
Externí odkaz:
https://doaj.org/article/02df4a49d2314ca5a9d8b39bd4826aa0
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110621- (2022)
Summary: Liver sinusoidal endothelial cells (LSECs) form the predominant microvasculature in the liver where they carry out many functions including the secretion of coagulation factor VIII (FVIII). To investigate the early origins of this lineage, w
Externí odkaz:
https://doaj.org/article/4c3bf17d63b045ebae5e9f46262222b8
Autor:
Michael H. Atkins, Rebecca Scarfò, Kathleen E. McGrath, Donghe Yang, James Palis, Andrea Ditadi, Gordon M. Keller
Publikováno v:
Journal of Experimental Medicine. 219
In the mouse, the first hematopoietic cells are generated in the yolk sac from the primitive, erythro-myeloid progenitor (EMP) and lymphoid programs that are specified before the emergence of hematopoietic stem cells. While many of the yolk sac–der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2a6f0bfe3e99207e6a4fb665c50b84
https://doi.org/10.1084/jem.20211924
https://doi.org/10.1084/jem.20211924
Autor:
Donghe Yang, Juliana Gomez-Garcia, Shunsuke Funakoshi, Thinh Tran, Ian Fernandes, Gary D. Bader, Michael A. Laflamme, Gordon M. Keller
Publikováno v:
Cell stem cell. 29(9)
The cardiomyocyte (CM) subtypes in the mammalian heart derive from distinct lineages known as the first heart field (FHF), the anterior second heart field (aSHF), and the posterior second heart field (pSHF) lineages that are specified during gastrula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c6c885aac3b77312fbcb66122f06d2
https://pubmed.ncbi.nlm.nih.gov/36055186
https://pubmed.ncbi.nlm.nih.gov/36055186
Autor:
Jessica A DeQuach, Valeria Mezzano, Amar Miglani, Stephan Lange, Gordon M Keller, Farah Sheikh, Karen L Christman
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13039 (2010)
The native extracellular matrix (ECM) consists of a highly complex, tissue-specific network of proteins and polysaccharides, which help regulate many cellular functions. Despite the complex nature of the ECM, in vitro cell-based studies traditionally
Externí odkaz:
https://doaj.org/article/5e0b0186325c4c18aca2e3a65329f57d
Publikováno v:
Methods in molecular medicine. 63
Under appropriate culture conditions, ES cells will spontaneously differentiate and generate colonies known as embryoid bodies (EBs) that contain precursors of multiple lineages, including those of the hematopoietic system (1-7). Previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7095d14768352135b200528c4fc90d73
https://pubmed.ncbi.nlm.nih.gov/21437810
https://pubmed.ncbi.nlm.nih.gov/21437810
Autor:
Marion, Kennedy, Gordon M, Keller
Publikováno v:
Methods in enzymology. 365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7212de8bfa591bb92ca607bac3b8d14
https://pubmed.ncbi.nlm.nih.gov/14696336
https://pubmed.ncbi.nlm.nih.gov/14696336
Publikováno v:
Methods in enzymology. 365
A reliable and effective in vitro differentiation system is described for the production of functional neutrophils from mouse embryonic stem (ES) cells. A three-step culture method was developed that enables abundant production and effective harvesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d97cef288ad6d81ece5c0d622869651d
https://pubmed.ncbi.nlm.nih.gov/14696342
https://pubmed.ncbi.nlm.nih.gov/14696342