Výsledky vyhledávání - "Gordon L. Williams"

1-Ethyl-1,4-dihydro-4-oxo-7-(pyridinyl)-3-quinolinecarboxylic acids. II. Synthesis

Autor: Philip M. Carabateas, Karl O. Gelotte, Chester Joseph Opalka, Roman R. Lorenz, Baldev Singh, William H. Thielking, Monte D. Gruett, George Y. Lesher, Gordon L. Williams, R. Pauline Brundage

Publikováno v: Journal of Heterocyclic Chemistry. 21:1857-1863

The preparation of a variety of 1-ethyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids with a range of substituents on the pyridine ring is described. Starting with the appropriately substituted aniline and using the first two steps of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e4529e66b78d9abdab860f05cc70b0a
https://doi.org/10.1002/jhet.5570210655

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1-Ethyl-1,4-dihydro-4-oxo-7-(pyridinyl)-3-quinolinecarboxylic acids. I. Synthesis of 3- and 4-(3-aminophenyl)pyridine intermediates

Autor: Chester Joseph Opalka, Roman R. Lorenz, R. Pauline Brundage, George Y. Lesher, Gordon L. Williams, Baldev Singh, William H. Thielking, Philip M. Carabateas, Karl O. Gelotte, Monte D. Gruett

Publikováno v: Journal of Heterocyclic Chemistry. 21:1849-1856

A series of substituted 3- and 4-(3-aminophenyl)pyridines has been prepared as intermediates for the synthesis of some 1-alkyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. The Hantzsch, Hauser and other pyridine syntheses were used. 4-(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2810a60897f05a0eb72d213bf0a0848f
https://doi.org/10.1002/jhet.5570210654

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Early Extracellular Events in Infection of Competent Bacillus subtilis by DNA of Bacteriophage SP82G

Autor: D. Macdonald Green, Gordon L. Williams

Publikováno v: Proceedings of the National Academy of Sciences. 69:1545-1549

Analysis, by the recovery of specific genetic “markers,” of the effects of DNase I, physical shear, and temperature shock on DNA-cell complexes demonstrates that sequential attachment of both ends of bacteriophage SP82G DNA to Bacillus subtilis p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b017f97afcfd8d1f50461ad4e92b7819
https://doi.org/10.1073/pnas.69.6.1545

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Antiviral activity of some beta-diketones. 2. Aryloxy alkyl diketones. In vitro activity against both RNA and DNA viruses

Autor: Guy D. Diana, U. Joseph Salvador, Ethel S. Zalay, Philip M. Carabateas, Gordon L. Williams, Joseph C. Collins, Francis Pancic

Publikováno v: Journal of medicinal chemistry. 20(6)

A series of aryloxy alkyl diketones II was synthesized and screened in vitro for antiviral activity. The effect of various substituents on the phenyl ring, as well as the length of the alkyl bridge, was examined to establish the requirements for opti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee30849a75294ff6451cb962e2f17aa
https://pubmed.ncbi.nlm.nih.gov/195055

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Antiviral activity of some beta-diketones. 3. Aryl bis(beta-diketones). Antiherpetic activity

Autor: Gordon L. Williams, U. Joseph Salvador, E. S. Zalay, Joseph C. Collins, Francis Pancic, B. A. Steinberg, Guy D. Diana, Philip M. Carabateas

Publikováno v: Journal of medicinal chemistry. 21(7)

A series of bis(beta-diketones) was synthesized and tested in vitro for antiviral actitity against herpes simplex type 2. Two parameters which were studied in an effort to optimize activity were the nature of the aryl group and the length of the alky

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf804371f357d09f9b34050041eff76
https://pubmed.ncbi.nlm.nih.gov/209188

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Tetraethyl 4-(3-nitrophenyl)-2,3,5,6-pyridinetetracarboxylate

Autor: Philip M. Carabateas, Gordon L. Williams

Publikováno v: Journal of Heterocyclic Chemistry. 13:927-928

Reaction of 3-nitrobenzaldehyde with diethyl oxalacetate in the presence of piperidine acetate and then ammonium acetate/acetic acid gave a moderate yield of tetraethyl 1,4-dihydro-4-(3-nitrophenyl)-2,3,5,6-pyridinetetracarboxylate. This was oxidized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::509264f3061ed44ed195488248390f7a
https://doi.org/10.1002/jhet.5570130451

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