Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gordon L. Lange"'
Autor:
Michael G. Organ, Gordon L. Lange
Publikováno v:
Synlett. 31:665-667
Publikováno v:
Tetrahedron: Asymmetry. 13:1355-1362
Three chiral 2,5-cyclohexadienone synthons bearing different chiral auxiliaries were examined in [2+2] photoadditions with cyclopentene. Regeneration of the ‘masked’ double bond in the adducts resulted in the preparation of optically active 5-4-6
Autor:
Alexandru Merica, Gordon L. Lange
Publikováno v:
Tetrahedron Letters. 40:7897-7900
A radical fragmentation/cyclization sequence of a [2+2] photoadduct derivative leads to the formation of the aromadendrane ring system. The 5,7 fused rings of this sesquiterpenoid family are formed in the fragmentation step and the cyclopropane moiet
Autor:
Nijsiri Ruangrungsi, Arunporn Itharat, Gordon L. Lange, Kanokkan Intarit, Chaweewan Jansakul, Thatree Phadungcharoen, Alexandru Merica
Publikováno v:
Pharmaceutical Biology. 37:42-45
Ursolic acid (1), pseudoginsenoside-RP 1 (2), and pseudoginsenoside-RT 1 (3) were isolated from the fruit of Randia siamensis. 13 C NMR spectroscopy was particularly useful in confirming the structures of these components. Studies with rats showed th
Autor:
Gordon L. Lange, Nadia Corelli
Publikováno v:
Tetrahedron Letters. 48:1963-1965
A radical reaction of a tetracyclic iodide results in a tandem cyclobutylcarbinyl/cyclopropylcarbinyl fragmentation sequence to generate the framework of the sesquiterpenoid lactarane family.
Publikováno v:
Tetrahedron Letters. 39:5489-5492
A highly regio- and stereoselective synthesis of the sesquiterpenoid trichodiene is reported. The approach requires only nine steps starting with a [2+2] photoaddition and employs the free radical fragmentation of an “external” cyclobutane bond i
Autor:
Gordon L. Lange, Alexandru Merica
Publikováno v:
Tetrahedron Letters. 39:3639-3642
Preparation of highly functionalized 16 constitutes one of the first attempts at the synthesis of the A/B carbon skeleton of the 11(15→1)-abeotaxanes. Further transformations of labile 16 give enedione 17 , an important relay compound in the synthe
Publikováno v:
Tetrahedron Letters. 38:6371-6374
The trinor-guaiane sesquiterpenoid (±)-dictammol 2 was synthesized, in only 6 steps, from photoadduct 5. The crucial step involved a SmI2-mediated tandem free radical fragmentation/elimination reaction of diiodide 10. Support for the recently revise
Autor:
Christine Gottardo, Gordon L. Lange
Publikováno v:
Magnetic Resonance in Chemistry. 34:660-666
Autor:
Michael G. Organ, Gordon L. Lange
Publikováno v:
The Journal of Organic Chemistry. 61:5358-5361
The [2 + 2] photoaddition of 2-cyclopentenones with derivatives of the cyclic β-keto ester 1 was investigated. The resultant adducts then underwent fragmentation to 5/8 fused ring systems present in terpenoid natural products such as asteriscanolide