Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Gordon L Fain"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300584 (2024)
Though rod and cone photoreceptors use similar phototransduction mechanisms, previous model calculations have indicated that the most important differences in their light responses are likely to be differences in amplification of the G-protein cascad
Externí odkaz:
https://doaj.org/article/d0303dcee5a74ef18ee94187829a15a0
Autor:
Gordon L. Fain
Molecular and Cellular Physiology of Neurons: Second Edition is a comprehensive, up-to-date introduction to essential concepts of cellular neuroscience. Emphasizing experimental approaches and recent discoveries, it provides an in-depth look at the s
Autor:
Gordon L. Fain
After Sappho but before the great Latin poets, the most important short poems in the ancient world were Greek epigrams. Beginning with simple expressions engraved on stone, these poems eventually encompassed nearly every theme we now associate with l
Autor:
Gordon L. Fain
Publikováno v:
Current biology : CB. 32(13)
Mice detect decreases in illumination in dim light near the visual threshold with OFF retinal ganglion cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced71eae241313efbf162c414c049df5
https://pubmed.ncbi.nlm.nih.gov/35609606
https://pubmed.ncbi.nlm.nih.gov/35609606
Autor:
Joanna J. Kaylor, Tongzhou Xu, Norianne T. Ingram, Avian Tsan, Hayk Hakobyan, Gordon L. Fain, Gabriel H. Travis
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
It is currently thought that visual pigments in vertebrate photoreceptors are regenerated exclusively through enzymatic cycles. Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of
Externí odkaz:
https://doaj.org/article/1627c4ab61794e10891586d484023cf9
Autor:
Ala Morshedian, Gabriela Sendek, Sze Yin Ng, Kimberly Boyd, Roxana A. Radu, Mingyao Liu, Nikolai O. Artemyev, Alapakkam P. Sampath, Gordon L. Fain
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 11
J Neurosci
J Neurosci
The high sensitivity of night vision requires that rod photoreceptors reliably and reproducibly signal the absorption of single photons, a process that depends on tight regulation of intracellular cGMP concentration through the phototransduction casc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aee363012006ca0a1a9894e1d711434
https://doi.org/10.1523/jneurosci.2119-21.2021
https://doi.org/10.1523/jneurosci.2119-21.2021
Autor:
Ala Morshedian, Matthew B. Toomey, Gabriel E. Pollock, Rikard Frederiksen, Jennifer M. Enright, Stephen D. McCormick, M. Carter Cornwall, Gordon L. Fain, Joseph C. Corbo
Publikováno v:
Royal Society Open Science, Vol 4, Iss 7 (2017)
The spectral composition of ambient light varies across both space and time. Many species of jawed vertebrates adapt to this variation by tuning the sensitivity of their photoreceptors via the expression of CYP27C1, an enzyme that converts vitamin A1
Externí odkaz:
https://doaj.org/article/bdc7e89cfc6a4192be0f1302c9bb0f4b
Autor:
Erika M. Ellis, Antonio E. Paniagua, Miranda L. Scalabrino, Mishek Thapa, Jay Rathinavelu, Yuekan Jiao, David S. Williams, Greg D. Field, Gordon L. Fain, Alapakkam P. Sampath
Most defects causing retinal degeneration in retinitis pigmentosa (RP) are rod-specific mutations, but the subsequent degeneration of cones, which produces loss of daylight vision and high-acuity perception, is the most debilitating feature of the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f3af2c54fabd6747fe103f1b5d92d
https://doi.org/10.1101/2022.09.27.509752
https://doi.org/10.1101/2022.09.27.509752
Publikováno v:
The Journal of Physiology
The Journal of Physiology, 2021, 599 (13), pp.3295-3312. ⟨10.1113/JP281225⟩
J Physiol
The Journal of Physiology, Wiley, 2021, 599 (13), pp.3295-3312. ⟨10.1113/JP281225⟩
The Journal of Physiology, 2021, 599 (13), pp.3295-3312. ⟨10.1113/JP281225⟩
J Physiol
The Journal of Physiology, Wiley, 2021, 599 (13), pp.3295-3312. ⟨10.1113/JP281225⟩
Most vertebrate eyes have rod and cone photoreceptors, which use a signal transduction pathway consisting of many biological processes to transform light into an electrical response. We dissect and quantify the contribution of each of these processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069e53686c9fe8987357abf91d58cd5e
https://doi.org/10.1113/jp281225
https://doi.org/10.1113/jp281225
Autor:
Katherine E. Fehlhaber, Anurima Majumder, Kimberly K. Boyd, Khris G. Griffis, Nikolai O. Artemyev, Gordon L. Fain, Alapakkam P. Sampath
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8106
Mammalian UNC119 is a ciliary trafficking chaperone highly expressed in the inner segment of retinal photoreceptors. Previous research has shown that UNC119 can bind to transducin, the synaptic ribbon protein RIBEYE, and the calcium-binding protein C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bcb0b61c74006f754f2475ba3fd80b
https://doi.org/10.3390/ijms24098106
https://doi.org/10.3390/ijms24098106