Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Gordon L Carlson"'
Autor:
Geoffrey Warhurst, Graham Dunn, Paul Chadwick, Bronagh Blackwood, Daniel McAuley, Gavin D Perkins, Ronan McMullan, Simon Gates, Andrew Bentley, Duncan Young, Gordon L Carlson, Paul Dark
Publikováno v:
Health Technology Assessment, Vol 19, Iss 35 (2015)
Background: There is growing interest in the potential utility of real-time polymerase chain reaction (PCR) in diagnosing bloodstream infection by detecting pathogen deoxyribonucleic acid (DNA) in blood samples within a few hours. SeptiFast (Roche Di
Externí odkaz:
https://doaj.org/article/42fb314aec824449af2080cd49d2765c
Autor:
Ramya Kalaiselvan, Dominic A. J. Slade, Mattias Soop, Hugh Burnett, Nicholas P. Lees, Iain D. Anderson, Simon Lal, Gordon L. Carlson
Publikováno v:
Colorectal Disease. 25:111-117
The effect of negative pressure wound therapy (NPWT) on the pathogenesis and outcome of enteroatmospheric fistulation (EAF) in the septic open abdomen (OA) is unclear. This study compares the development and outcome of EAF following NPWT with that oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f85f6d922eb081ec36740f3854f8ab
https://doi.org/10.1111/codi.16318
https://doi.org/10.1111/codi.16318
Autor:
Paul Dark, Gavin D Perkins, Ronan McMullan, Danny McAuley, Anthony C Gordon, Jonathan Clayton, Dipesh Mistry, Keith Young, Scott Regan, Nicola McGowan, Matt Stevenson, Simon Gates, Gordon L Carlson, Tim Walsh, Nazir I Lone, Paul R Mouncey, Mervyn Singer, Peter Wilson, Tim Felton, Kay Marshall, Anower M. Hossain, Ranjit Lall
Publikováno v:
Dark, P, Carlson, G L, Felton, T & Marshall, K 2023, ' biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial ', Journal of the Intensive Care Society . https://doi.org/10.1177/17511437231169193
Aim: To describe the protocol for a multi-centre randomised controlled trial to determine whether treatment protocols monitoring daily CRP (C-reactive protein) or PCT (procalcitonin) safely allow a reduction in duration of antibiotic therapy in hospi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c533363e8bd8e00ab92c176bed921bf9
https://doi.org/10.1177/17511437231169193
https://doi.org/10.1177/17511437231169193
Autor:
Amin Rostami-Hodjegan, Jill Barber, Gordon L Carlson, Narciso Couto, Zubida M. Al-Majdoub, Matthew D Harwood, Brahim Achour, Geoffrey Warhurst
Publikováno v:
Clinical Pharmacology and Therapeutics
Al-Majdoub, Z, Couto, N, Achour, B, Harwood, M D, Carlson, G, Warhurst, G, Barber, J & Rostami-Hodjegan, A 2021, ' Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics ', Clinical Pharmacology & Therapeutics, vol. 109, no. 4, pp. 1136-1146 . https://doi.org/10.1002/cpt.2097
Al-Majdoub, Z, Couto, N, Achour, B, Harwood, M D, Carlson, G, Warhurst, G, Barber, J & Rostami-Hodjegan, A 2021, ' Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics ', Clinical Pharmacology & Therapeutics, vol. 109, no. 4, pp. 1136-1146 . https://doi.org/10.1002/cpt.2097
The intestinal epithelium represents a natural barrier against harmful xenobiotics, whilst facilitating the uptakeof nutrients and other substances. Understanding the interaction of chemicals with constituents of theintestinal epithelium and their fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9783d9ffb9979685b70835a0ca42ee
https://doi.org/10.1002/cpt.2097
https://doi.org/10.1002/cpt.2097
Publikováno v:
BJS Open. 6
Background Rectus sheath catheter analgesia (RSCA) and thoracic epidural analgesia (TEA) are both used for analgesia following laparotomy. The aim was to compare the analgesic effectiveness of RSCA with TEA after laparotomy for elective colorectal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d87b514886d08b921dd1c545d09c167
https://doi.org/10.1093/bjsopen/zrac055
https://doi.org/10.1093/bjsopen/zrac055
Autor:
Stephanie L Gibson, Gordon L Carlson, P. Davies, Zubida M. Al-Majdoub, Matthew D Harwood, Brahim Achour, Geoffrey Warhurst, Jill Barber, Amin Rostami-Hodjegan, Narciso Couto
Publikováno v:
Drug Metabolism and Disposition
Drug Metab Dispos
Drug Metab Dispos
The levels of drug-metabolizing enzymes (DMEs) and transporter proteins in the human intestine are pertinent to determine oral drug bioavailability. Despite the paucity of reports on such measurements, it is well recognized that these values are esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d21e6154864c277c98ec478eecfff
http://europepmc.org/articles/PMC7076527
http://europepmc.org/articles/PMC7076527
Autor:
Antje Teubner, Gordon L. Carlson, Simon Lal, Emma Nixon, Haroon Khan, Mattias Soop, Arun Abraham
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Intestinal failure [IF] is a feared complication of Crohn’s disease [CD]. Although cumulative loss of small bowel due to bowel resections is thought to be the dominant cause, the causes and outcomes have not been reported. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef83bfa48dac54a1e70c3a325fbdbe9
https://doi.org/10.1093/ecco-jcc/jjaa060
https://doi.org/10.1093/ecco-jcc/jjaa060
Autor:
J. Varden, Michael Taylor, Gordon L Carlson, Paul R. Chadwick, Arun Abraham, Antje Teubner, Simon Lal, Mattias Soop, Ashley Bond, C. Cawley
Publikováno v:
Clinical Nutrition. 38:1828-1832
Summary Introduction The management of intestinal failure (IF) requires safe and sustained delivery of parenteral nutrition (PN). The long-term maintenance of central venous catheter (CVC) access is therefore vital, with meticulous catheter care and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07068305cb7fde2741163bafbab2016c
https://doi.org/10.1016/j.clnu.2018.07.019
https://doi.org/10.1016/j.clnu.2018.07.019
Publikováno v:
Colorectal Disease. 22:129-135
Aim Type IV Ehlers Danlos Syndrome (EDS) is a connective tissue disorder affecting approximately 1 per 100,000-200,000 people. Life expectancy is reduced secondary to spontaneous vascular rupture or colonic perforation. Surgery carries significant mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38122b856419ca81fbac2da5843ffbc0
https://doi.org/10.1111/codi.14749
https://doi.org/10.1111/codi.14749
Autor:
L. Fligelstone, J. Keating, David Jayne, C. P. Shearman, M. Gill, Gordon L Carlson, S. Renton
Publikováno v:
The British Journal of Surgery
Background Patients undergoing prolonged pelvic surgery may develop compartment syndrome of one or both lower limbs in the absence of direct trauma or pre-existing vascular disease (well leg compartment syndrome). This condition may have devastating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b35487c4b5e55bcc723d76e6de1007b
https://doi.org/10.1002/bjs.11177
https://doi.org/10.1002/bjs.11177