Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gordon K. Li"'
Publikováno v:
Journal of Biological Chemistry. 284:32209-32224
ADP responses underlie therapeutic approaches to many cardiovascular diseases, and ADP receptor antagonists are in widespread clinical use. The role of ADP in platelet biology has been extensively studied, yet ADP signaling pathways in endothelial ce
Publikováno v:
Journal of Biological Chemistry. 282:20351-20364
The endothelial isoform of nitric-oxide synthase (eNOS), a key determinant of vascular homeostasis, is a calcium/calmodulin-dependent phosphoprotein regulated by diverse cell surface receptors. Vascular endothelial growth factor (VEGF) and sphingosin
Autor:
Ralph A. Kelly, Thomas Michel, Charles I. Berul, Gordon K. Li, Amit Rakhit, T B S Colin Maguire, Josef Gehrmann, Hiroko Wakimoto
Publikováno v:
Journal of Cardiovascular Electrophysiology. 12:1295-1301
Electrophysiologic Studies in eNOS-Deficient Mice.Introduction: Endothelial nitric oxide synthase (eNOS) mediates attenuation of the L-type calcium channel and modulates myocyte contractility. Arrhythmogenic afterdepolarizations are seen in vitro in
Publikováno v:
Proceedings of the National Academy of Sciences. 90:6252-6256
In the vascular endothelium, diverse cell surface receptors are coupled to the Ca2+/calmodulin-dependent activation of nitric oxide (NO) synthase. We now report that, in intact cultured endothelial cells, several drugs and agonists are associated wit
Publikováno v:
The Journal of biological chemistry. 284(47)
ADP responses underlie therapeutic approaches to many cardiovascular diseases, and ADP receptor antagonists are in widespread clinical use. The role of ADP in platelet biology has been extensively studied, yet ADP signaling pathways in endothelial ce
Publikováno v:
The Journal of biological chemistry. 282(28)
The endothelial isoform of nitric-oxide synthase (eNOS), a key determinant of vascular homeostasis, is a calcium/calmodulin-dependent phosphoprotein regulated by diverse cell surface receptors. Vascular endothelial growth factor (VEGF) and sphingosin
Publikováno v:
Scopus-Elsevier
Nitric oxide (NO) is a ubiquitous intercellular messenger molecule synthesized from the amino acid L-arginine by NO synthases in diverse cells and tissues. NO is synthesized in vascular endothelial cells and appears to play an important role in the c
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