Zobrazeno 1 - 10
of 10 215
pro vyhledávání: '"Gordon K"'
Autor:
Pooja S. Yesantharao, MD, MS, Trudy Kim, BS, Priscila C. Cevallos, BS, Gordon K. Lee, MD MBA, Rahim S. Nazerali, MD, MHS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss S5, Pp 144-145 (2024)
Externí odkaz:
https://doaj.org/article/742e0be09d954e70b09c86cfa89f2177
Autor:
Pooja S. Yesantharao, MD, MS, Trudy Kim, BS, Priscila C. Cevallos, BS, Gordon K. Lee, MD MBA, Rahim S. Nazerali, MD MHS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss S4, Pp 2-3 (2024)
Externí odkaz:
https://doaj.org/article/1bbbdcfb90c943ed88d9eebe4e0144ab
Autor:
Mitra Ashayeripanah, Javier Vega-Ramos, Daniel Fernandez-Ruiz, Shirin Valikhani, Aaron T.L. Lun, Jason T. White, Louise J. Young, Atefeh Yaftiyan, Yifan Zhan, Linda Wakim, Irina Caminschi, Mireille H. Lahoud, Andrew M. Lew, Ken Shortman, Gordon K. Smyth, William R. Heath, Justine D. Mintern, Antoine Roquilly, Jose A. Villadangos
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113754- (2024)
Summary: Blood-borne pathogens can cause systemic inflammatory response syndrome (SIRS) followed by protracted, potentially lethal immunosuppression. The mechanisms responsible for impaired immunity post-SIRS remain unclear. We show that SIRS trigger
Externí odkaz:
https://doaj.org/article/531a91054c1e4bb68aeda10b35050804
Autor:
Yue You, Xueyi Dong, Yong Kiat Wee, Mhairi J. Maxwell, Monther Alhamdoosh, Gordon K. Smyth, Peter F. Hickey, Matthew E. Ritchie, Charity W. Law
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Group heteroscedasticity is commonly observed in pseudo-bulk single-cell RNA-seq datasets and its presence can hamper the detection of differentially expressed genes. Since most bulk RNA-seq methods assume equal group variances, we introduce
Externí odkaz:
https://doaj.org/article/d10773884bdb4c46881828200216a0c4
Publikováno v:
F1000Research, Vol 12 (2023)
Background Single-cell RNA sequencing (scRNA-seq) technologies have rapidly developed in recent years. The droplet-based single cell platforms enable the profiling of gene expression in tens of thousands of cells per sample. The goal of a typical scR
Externí odkaz:
https://doaj.org/article/60fa91c5b0c2430ca3a63601595c6b54
Autor:
Sargun Sokhi, Cody W. Lewis, Amirali B. Bukhari, Joanne Hadfield, Edric J. Xiao, Jeremy Fung, Yea Jin Yoon, Wen-Hsin Hsu, Armin M. Gamper, Gordon K. Chan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell cycle checkpoint kinases serve as important therapeutic targets for various cancers. When they are inhibited by small molecules, checkpoint abrogation can induce cell death or further sensitize cancer cells to other genotoxic therapies. Particul
Externí odkaz:
https://doaj.org/article/bb42fe2ab7be453fa00e30cc0aa196a6
Autor:
Sri Harshini Malapati, BS, Elie P. Ramly, MD, Johanna Riesel, MD, Andrea L. Pusic, MD, Gordon K. Lee, MD, William P. Magee, MD, Peter M. Nthumba, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 9, p e5256 (2023)
Background:. The need to address inequities in global surgical care has garnered increased attention since 2015, after the Lancet Commission on Global Surgery underscored the importance of ensuring safe, accessible, affordable, and timely surgical an
Externí odkaz:
https://doaj.org/article/8b2a8021ae9242d797d0b6081338d68b
Autor:
Wing Fuk Chan, Hannah D. Coughlan, Yunshun Chen, Christine R. Keenan, Gordon K. Smyth, Andrew C. Perkins, Timothy M. Johanson, Rhys S. Allan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Stably silenced genes with methylated CpG at the promoter are refractory to current CRISPR activation systems. Here the authors create a more robust activation system, TETact that recruits DNA-demethylating TET1 with transcriptional activators.
Externí odkaz:
https://doaj.org/article/aa28af5f1a0d4589a6f38a6f04cab4f2
Myokines Produced by Cultured Bovine Satellite Cells Harvested from 3- and 11-Month-Old Angus Steers
Autor:
Katie A. Shira, Brenda M. Murdoch, Kara J. Thornton, Caleb C. Reichhardt, Gabrielle M. Becker, Gwinyai E. Chibisa, Gordon K. Murdoch
Publikováno v:
Animals, Vol 14, Iss 5, p 709 (2024)
The myokines interleukin 6 (IL-6), interleukin 15 (IL-15), myonectin (CTRP15), fibronectin type III domain containing protein 5/irisin (FNDC5), and brain-derived neurotrophic factor (BDNF) are associated with skeletal muscle cell proliferation, diffe
Externí odkaz:
https://doaj.org/article/aa59ed7f39bb4320a35b6a0a079c7d04
Autor:
Johannes Wichmann, Catherine Pitt, Samantha Eccles, Alexandra L. Garnham, Connie S. N. Li-Wai-Suen, Rose May, Elizabeth Allan, Stephen Wilcox, Marco J. Herold, Gordon K. Smyth, Brendon J. Monahan, Tim Thomas, Anne K. Voss
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-13 (2022)
Abstract Histone acetylation is essential for initiating and maintaining a permissive chromatin conformation and gene transcription. Dysregulation of histone acetylation can contribute to tumorigenesis and metastasis. Using inducible cre-recombinase
Externí odkaz:
https://doaj.org/article/fa05505e61364d55b26a94489dc63e8d