Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gordon J. Hildick-Smith"'
Autor:
Gordon J. Hildick-Smith, Nicholas C. Huston, Paul J. Schmidt, Daniel A. Lichtenstein, Anoop K. Sendamarai, Chang Cao, Caiyong Chen, Andrew Crispin, Dean R. Campagna, Mark D. Fleming, Matthew M. Heeney, Sylvia S. Bottomley, Barry H. Paw, Sarah Ducamp, Jeanne Boudreaux, Chaoshe Guo
Publikováno v:
J Clin Invest
The congenital sideroblastic anemias (CSAs) can be caused by primary defects in mitochondrial iron-sulfur (Fe-S) cluster biogenesis. HSCB (heat shock cognate B), which encodes a mitochondrial cochaperone, also known as HSC20 (heat shock cognate prote
Autor:
Jane Chang, Gordon J. Hildick-Smith, Michael F. Pesko, Gerald M. Loughlin, Lee S. Shearer, Jenna M. Hughes, Lisa S. Ipp
Publikováno v:
Journal of Adolescent Health. 57:574-579
We present guidance on electronic nicotine delivery systems (ENDS) for health care professionals who care for adolescents. ENDS provide users with inhaled nicotine in an aerosolized mist. Popular forms of ENDS include e-cigarettes and vape-pens. ENDS
Autor:
Gordon J. Hildick-Smith, Tania A. Baker, Diana S. Branco, Nicholas C. Huston, Kyu Y. Rhee, Julia R. Kardon, Barry H. Paw, Yvette Y. Yien
Publikováno v:
PMC
The mitochondrion maintains and regulates its proteome with chaperones primarily inherited from its bacterial endosymbiont ancestor. Among these chaperones is the AAA+ unfoldase ClpX, an important regulator of prokaryotic physiology with poorly defin
Autor:
Leonard I. Zon, Owen J. Tamplin, Paul F. McBride, Kelli J. Carroll, Dhvanit I. Shah, Diana S. Branco, Ebrahim Shafizadeh, Gordon J. Hildick-Smith, Heidi Anderson, Clara Wong, Trista E. North, Barry H. Paw, Jeffrey D. Cooney, Patrick G. Gallagher, Arthur J. Dalton, George C. Shaw
Publikováno v:
Developmental Biology. 373:431-441
Growth Factor Independence (Gfi) transcription factors play essential roles in hematopoiesis, differentially activating and repressing transcriptional programs required for hematopoietic stem/progenitor cell (HSPC) development and lineage specificati
Autor:
Gordon J. Hildick-Smith, Babette Gwynn, Lionel Blanc, Steven L. Ciciotte, Eric L. Pierce, Luanne L. Peters, Barry H. Paw, Jeffrey D. Cooney, Kathleen A. Soltis
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12099-12104
Phenotype-driven approaches to gene discovery using inbred mice have been instrumental in identifying genetic determinants of inherited blood dyscrasias. The recessive mutant scat (severe combined anemia and thrombocytopenia) alternates between crisi
Publikováno v:
Carbohydrate Research. 345:2499-2506
Ribose 5-phosphate (R5P) is a sugar known to undergo the Maillard reaction (glycation) at a rapid rate. In a reaction with the lysines of bovine heart cytochrome c, R5P generates superoxide (O2-) that subsequently reduces ferri-cytochrome c to ferro-
Autor:
Sarah Ducamp, Gordon J. Hildick-Smith, Chang Cao, Mark D. Fleming, Dean R. Campagna, Chaoshe Guo, Caiyong Chen, Paul J. Schmidt, Barry H. Paw, Sylvia S. Bottomley, Jeanne Boudreaux, Matthew M. Heeney, Andrew Crispin, Daniel A. Lichtenstein, Nicolas C Huston, Anoop K. Sendamarai
Publikováno v:
Blood. 130:79-79
Congenital sideroblastic anemias (CSAs) are uncommon inherited diseases resulting from defects in heme biosynthesis, mitochondrial translation or mitochondrial iron-sulfur cluster (ISC) assembly. CSAs are characterized by pathological mitochondrial i
Autor:
Abhishek Dass, Eric A. Pierce, Daniel E. Bauer, Dhvanit I. Shah, Salvatore DiMauro, Barry H. Paw, Jeffrey D. Cooney, Hui Huang, Tamara A. Dailey, Naoko Takahashi-Makise, John Gary Phillips, Kyla Mohler, Yvette Y. Yien, Paul D. Kingsley, Thorsten M. Schlaeger, Harvey F. Lodish, Raymond F. Robledo, Wen Chen, Diane M. Ward, Stuart H. Orkin, Caterina Garone, Carla M. Koehler, Ellen M. Keenan, Iman J. Schultz, Gloria Yi, James Palis, Shilpa M. Hattangadi, Luanne L. Peters, Non Miyata, Jerry Kaplan, Alan B. Cantor, Babette Gwynn, Liangtao Li, Harry A. Dailey, Gordon J. Hildick-Smith
Publikováno v:
The Journal of clinical investigation, vol 124, iss 10
The transport and intracellular trafficking of heme biosynthesis intermediates are crucial for hemoglobin production, which is a critical process in developing red cells. Here, we profiled gene expression in terminally differentiating murine fetal li
Autor:
Wen Chen, Jerry Kaplan, Prem Ponka, Yvette Y. Yien, Caiyong Chen, Gordon J. Hildick-Smith, James Palis, Abigail Goodnow Dalton, Heidi Anderson, Daniel Garcia-Santos, Alexandra Seguin, Matthew L. Freedman, Darshan Anil Shah, Yuichi Ishikawa, Iman J. Schultz, Harvey F. Lodish, Matthew J. King, Takahiro Maeda, Jeffrey D. Cooney, Barry H. Paw, Shilpa M. Hattangadi, Paul D. Kingsley, Diane M. Ward, Katherine H. Fegan, Liangtao Li
Publikováno v:
PMC
Sorting of endocytic ligands and receptors is critical for diverse cellular processes. The physiological significance of endosomal sorting proteins in vertebrates, however, remains largely unknown. Here we report that sorting nexin 3 (Snx3) facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8070b94da2489943ac674439d7b9a7fd
http://hdl.handle.net/1721.1/86052
http://hdl.handle.net/1721.1/86052
Autor:
Gordon J. Hildick-Smith, Jenna M. Hughes, Lisa S. Ipp, Lee S. Shearer, Michael F. Pesko, Jane Chang, Gerald M. Loughlin
Publikováno v:
Journal of Adolescent Health. 58:586
We thank the authors Braillon and Nolte for suggesting a role for warning labels on disposable electronic nicotine delivery systems (ENDSs) and nicotine refill cartridges [1]. In April 2014, in a move that asserts jurisdiction over ENDS, the Food and