Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Gordon J. Gaschler"'
1
Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lungs
Autor: Gordon J. Gaschler, Carla M. T. Bauer, Martin R. Stämpfli, Caleb C. J. Zavitz
Publikováno v: European Respiratory Journal. 36:1131-1142
Inflammation is prevalent in all stages of chronic obstructive pulmonary disease, and, furthermore, individuals undergo periods of exacerbation, during which pulmonary inflammation increases, often a result of bacterial infection. The present study i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5b33df817623dce3dc1cec913069fa
https://doi.org/10.1183/09031936.00113909
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2
Innate Immune Processes Are Sufficient for Driving Cigarette Smoke–Induced Inflammation in Mice
Autor: Carla M. T. Bauer, Gordon J. Gaschler, Cale C. J. Zavitz, Martin R. Stämpfli, Sussan Kianpour, Nancy J. Trimble, Jake K. Nikota, Fernando M. Botelho
Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 42:394-403
The objective of this study was to characterize the impact of cigarette smoke exposure on lung immune and inflammatory processes. BALB/c and C57BL/6 mice were exposed to cigarette smoke for 4 days (acute) or at least 5 weeks (prolonged). Both mouse s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1240ffdc7b858b932d2e0408e8ee0c7f
https://doi.org/10.1165/rcmb.2008-0301oc
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3
Cigarette Smoke Impacts Immune Inflammatory Responses to Influenza in Mice
Autor: Gordon J. Gaschler, Earl G. Brown, Neda Vujicic, Clinton S. Robbins, Martin R. Stämpfli, Carla M. T. Bauer, Brian D. Lichty
Publikováno v: American Journal of Respiratory and Critical Care Medicine. 174:1342-1351
Studies have shown that cigarette smoke impacts respiratory host defense mechanisms; however, it is poorly understood how these smoke-induced changes impact the overall ability of the host to deal with pathogenic agents.The objective of this study wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4ee9b48a16218c8340970257a0f8b2
https://doi.org/10.1164/rccm.200604-561oc
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4
Impact of Cigarette Smoke on the Human and Mouse Lungs
Autor: Jean-Christophe Bérubé, Mathieu C. Morissette, James C. Hogg, Michel Laviolette, Maxime Lamontagne, Sabina Halappanavar, Christian Couture, Gordon J. Gaschler, Wim Timens, Andrew Williams, Yohan Bossé, Carole L. Yauk, Martin R. Stämpfli
Publikováno v: PLoS ONE, Vol 9, Iss 3, p e92498 (2014)
PLoS ONE, 9(3):e92498. PUBLIC LIBRARY SCIENCE
PLoS ONE
Cigarette smoke is well known for its adverse effects on human health, especially on the lungs. Basic research is essential to identify the mechanisms involved in the development of cigarette smoke-related diseases, but translation of new findings fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2f5efaabed38a3fcbbc918390a1822
https://doi.org/10.1371/journal.pone.0092498
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5
Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke
Autor: Lukas Didon, Gordon J. Gaschler, Martin R. Stämpfli, Magnus Nord, Jenny L. Barton, Carla M. T. Bauer, Abraham B. Roos, Tove Berg
Publikováno v: American journal of respiratory and critical care medicine. 184(2)
Cigarette smoke is the major cause of chronic obstructive pulmonary disease and lung cancer. The mechanisms by which smoking induces pulmonary dysfunction are complex, involving stress from toxic components and inflammatory responses. Although CCCAAT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4685bf8cbeb59145a192f507d85d3893
https://pubmed.ncbi.nlm.nih.gov/21562127
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10
Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile
Autor: Per-Ola Onnervik, Gordon J. Gaschler, Martin R. Stämpfli, Caleb C. J. Zavitz, Timothy F. Murphy, Maria Lindahl, Marko Skrtic, Sanjay Sethi
Publikováno v: American journal of respiratory and critical care medicine. 179(8)
The pathogenesis of chronic obstructive pulmonary disease is associated with acute episodes of bacterial exacerbations. The most commonly isolated bacteria during episodes of exacerbation is nontypeable Haemophilus influenzae (NTHI).In this study, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3285bbc039792eed06c7803ce25e80c
https://pubmed.ncbi.nlm.nih.gov/19179487
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