Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gordon Grochowy"'
Autor:
Eva Lessmann, Marcel Kuhny, Gerald Krystal, Carolin N. Zorn, Michael Leitges, Kerstin Fehrenbach, Gordon Grochowy, Michael Huber
Publikováno v:
The Journal of Immunology. 182:7897-7905
Ag-triggered mast cell (MC) activation follows a bell-shaped dose-response curve. Reduced activation in response to supraoptimal Ag concentrations is thought to be due to preferential engagement of inhibitory-acting proteins like SHIP1, Lyn, and prot
Autor:
Michael Huber, Chris Galanos, Gordon Grochowy, Wolfgang G. Bessler, Gerald Krystal, Fillip Port, Christoph Kalis, Marina A. Freudenberg, Kerstin Fehrenbach
Publikováno v:
Molecular Immunology. 44:2087-2094
Little is known about the interplay between pathophysiological processes of allergy and infection, particularly with respect to mast cell (MC)-mediated responses. The presence and recognition of pathogen-associated molecular patterns (PAMPs) might ha
Publikováno v:
Cellular signalling. 21(8)
The receptor-like protein tyrosine phosphatase CD45, the most abundant cell surface phosphatase on all nucleated hemopoietic cells, is a critical regulator of the activation status of Src family kinases (SFKs). To study the impact of CD45 on mast cel
Autor:
Kerstin, Fehrenbach, Fillip, Port, Gordon, Grochowy, Christoph, Kalis, Wolfgang, Bessler, Chris, Galanos, Gerald, Krystal, Marina, Freudenberg, Michael, Huber
Publikováno v:
Molecular immunology. 44(8)
Little is known about the interplay between pathophysiological processes of allergy and infection, particularly with respect to mast cell (MC)-mediated responses. The presence and recognition of pathogen-associated molecular patterns (PAMPs) might ha
Autor:
Torsten Giesemann, Michael Huber, Eva Lessmann, Michael Leitges, Klaus Aktories, Gerald Krystal, Gordon Grochowy, Lars Weingarten
Publikováno v:
Experimental hematology. 34(11)
Objective Mast cells (MCs) play central roles for the onset and development of immediate-type and inflammatory allergic reactions. Since the inverse relationship between atopic disorders and diabetes mellitus has been observed in animals and humans,