Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gordon F. Kapke"'
Publikováno v:
International Journal of Biological Sciences, Vol 5, Iss 2, Pp 128-134 (2009)
Urinary kidney injury molecule (KIM-1) is a sensitive quantitative biomarker for early detection of kidney tubular injury. The objective of the present work was to analytically validate this urinary renal injury biomarker. Duo-set reagents from R&D w
Externí odkaz:
https://doaj.org/article/671a59a913c34b928638d1c76d2c7611
Publikováno v:
International Journal of Biological Sciences
A major concern with the identification of renal toxicity using the traditional biomarkers, urea and creatinine, is that toxicity signal definitions are not sensitive to medically important changes in these biomarkers. Traditional renal signal defini
Publikováno v:
Drug Information Journal. 43:139-150
Assessment of whether laboratory results in clinical studies are abnormal relies heavily on the laboratory upper or lower reference limits. While central laboratories use a single reference interval for an entire study population, local laboratories
Publikováno v:
International Journal of Biological Sciences
Urinary kidney injury molecule (KIM-1) is a sensitive quantitative biomarker for early detection of kidney tubular injury. The objective of the present work was to analytically validate this urinary renal injury biomarker. Duo-set reagents from R&D w
Autor:
Christine M. Hunt, Amy T Heath, Gordon F. Kapke, Lynne Hamm, Susan C. Sorrells, Allen W. Mangel, Jacqueline Harding, Northcutt Allison Ruth
Publikováno v:
American Journal of Gastroenterology. 94:1279-1282
OBJECTIVE: Irritable bowel syndrome (IBS) is diagnosed by the presence of a constellation of symptoms fulfilling the Manning or Rome Criteria, after exclusion of organic disease. To exclude other diagnoses that might contribute to the abdominal pain
Publikováno v:
Clinical chemistry. 58(11)
BACKGROUND A concern with using creatinine for the identification of drug-induced renal impairment is that small changes in serum creatinine (SCr) that frequently are perceived as measurement bias or imprecision translate into important changes in th
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 158(6)
Although hemoglobin concentration measurement is among the most commonly performed blood tests, the description of global population parameters, heterogeneous factors, and within-subject variations in patients with disease remains incomplete. As abso
Autor:
Gordon F. Kapke, Lorraine Comanor, James M. Minor, Mel Krajden, Anna Grigoriew, Oretta Rifkin
Publikováno v:
Journal of clinical microbiology. 36(2)
Quantification of hepatitis B virus (HBV) DNA in serum is used to establish eligibility for treatment and to monitor therapeutic response. With the trend toward centralized testing, defining the conditions that preserve sample integrity is of paramou
Autor:
Ray B. Franklin, Gordon F. Kapke
Publikováno v:
Journal of Liquid Chromatography. 10:451-463
A rapid sensitive method for serum caffeine analysis is reported. One hundred microliters of serum is mixed with 50 microliters of the acetonitrile/internal standard mixture, centrifuged, and 10 microliters of the supernatant is injected into the liq
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 540:443-454
Adrenal ferredoxin, the iron-sulfur protein associated with cytochromes P -450 in adrenocortical mitochondria, has been localized immunohistochemically at the light microscopic level in rat adrenals by employing rabbit antiserum to bovine adrenal fer