Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Gordon F. Burns"'
Autor:
Charles E. de Bock, Michelle Down, Kinsha Baidya, Bram Sweron, Andrew W. Boyd, Mark Fiers, Gordon F. Burns, Timothy J. Molloy, Richard B. Lock, Jean Soulier, Tom Taghon, Pieter Van Vlierberghe, Jan Cools, Jeff Holst, Rick F. Thorne
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/917739d4aa2b4d259a4011e995e0cec1
Autor:
Gordon F. Burns, Rick F. Thorne, Charles E. de Bock, Nizar M. Mhaidat, Andrew W. Boyd, Kylie J. Ralston, Xudong Zhang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1803(11):1298-1307
CD36/FAT is a transmembrane glycoprotein that functions in the cellular uptake of long-chain fatty acids and also as a scavenger receptor. As such it plays an important role in lipid homeostasis and, pathophysiologically, in the progression of type 2
Publikováno v:
Biochemical and Biophysical Research Communications. 356:306-311
Membrane microdomains, or rafts, at the plasma membrane have been invoked to explain many cellular processes. Protein-protein interactions within such microdomains including, for example, the tetraspanin web are reported to provide a scaffold for sig
Publikováno v:
FEBS Letters. 581:1227-1232
Atherosclerotic plaques result from the excessive deposition of cholesterol esters derived from lipoproteins and lipoprotein fragments. Tissue macrophage within the intimal space of major arterial vessels have been shown to play an important role in
Autor:
Shirley I. Smith, Kylie J. Ralston, Gordon F. Burns, Maryanne Power, Mark D. Spanevello, Andrew W. Boyd, Michelle Down
Publikováno v:
Gene Expression Patterns. 5:483-490
The cadherin superfamily members play an important role in mediating cell-cell contact and adhesion (Takeichi, M., 1991. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455). A distinct subfamily, neither belonging t
Autor:
Rick F. Thorne, Ian R. Hart, John Marshall, Gordon F. Burns, Peter G. Gibson, Darren R. Shafren
Publikováno v:
Journal of Biological Chemistry. 275:35264-35275
Lateral association between different transmembrane glycoproteins can serve to modulate integrin function. Here we characterize a physical association between the integrins α3β1 and α6β1 and CD36 on the surface of melanoma cells and show that ect
Autor:
Gordon F. Burns, Douglas J. Dorahy
Publikováno v:
Biochemical Journal. 333:373-379
Circulating platelets are primed to respond very rapidly to thrombogenic stimuli, but most platelets complete their lifespan without ever becoming activated. Platelet activation is accompanied by waves of sequential tyrosine phosphorylation thought t
Autor:
Darren R. Shafren, Douglas J. Dorahy, Rick F. Thorne, Taroh Kinoshita, Richard D. Barry, Gordon F. Burns
Publikováno v:
The Journal of Immunology. 160:2318-2323
Decay-accelerating factor (DAF), a widely expressed membrane complement-regulatory protein, is utilized as a cellular receptor by many human enteric pathogens. We show here that the binding of two enteroviruses to individual short consensus repeats (
Autor:
Gordon F. Burns, Clifford J. Meldrum, Douglas J. Dorahy, Michael C. Berndt, Peter G. Gibson, Darren R. Shafren, Simon J. Harris, Rick F. Thorne
Publikováno v:
Biochemical and Biophysical Research Communications. 240:812-818
CD36 is a transmembrane glycoprotein expressed on the surface of a number of cell types. The analysis of CD36 from platelets using immunoblotting, gel filtration, and native PAGE indicated the presence of high molecular complexes exceeding the Mr of
Publikováno v:
Journal of Biological Chemistry. 272:1323-1330
Thrombospondin, a major secretory product of the alpha-granules of activated platelets, is a large trimeric glycoprotein that plays an important role in platelet aggregation. On resting platelets, thrombospondin binds to a single receptor in a cation