Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Gordon D. Ginder"'
Autor:
Xiaofei Yu, Alexander Azzo, Stephanie M. Bilinovich, Xia Li, Mikhail Dozmorov, Ryo Kurita, Yukio Nakamura, David C. Williams, Gordon D. Ginder
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
As high fetal hemoglobin levels ameliorate the underlying pathophysiological defects in sickle cell anemia and beta (β)-thalassemia, understanding the mechanisms that enforce silencing of fetal hemoglobin postnatally offers the promise of effective
Externí odkaz:
https://doaj.org/article/b50147ef6b95478dac7fc080db5ac0da
Autor:
Gordon D. Ginder, Harry D. Bear, Laura Graham, Merlin N. Gnanapragasam, Sheng Zu Zhu, Shou Zhen Wang, Omar Y. Mian
Methyl cytosine binding domain protein 2 (MBD2) has been shown to bind to and mediate repression of methylated tumor suppressor genes in cancer cells, where repatterning of CpG methylation and associated gene silencing is common. We have investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7665fc8403c0a7495b4e0ccc3a59ff
https://doi.org/10.1158/1541-7786.c.6542169.v1
https://doi.org/10.1158/1541-7786.c.6542169.v1
Autor:
Gordon D. Ginder, Harry D. Bear, Laura Graham, Merlin N. Gnanapragasam, Sheng Zu Zhu, Shou Zhen Wang, Omar Y. Mian
PDF file - 235K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a853116cd9b3c85c8b001b23e2ac31
https://doi.org/10.1158/1541-7786.22518891.v1
https://doi.org/10.1158/1541-7786.22518891.v1
Autor:
Gordon D. Ginder, Xia Li, Yukio Nakamura, David C. Williams, Alexander Azzo, Xiaofei Yu, Mikhail Dozmorov, Stephanie M. Bilinovich, Ryo Kurita
Publikováno v:
Haematologica. 104:2361-2371
As high fetal hemoglobin levels ameliorate the underlying pathophysiological defects in sickle cell anemia and beta (β)-thalassemia, understanding the mechanisms that enforce silencing of fetal hemoglobin postnatally offers the promise of effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e14b9eec016a8c5450441c8f73a797
https://doi.org/10.3324/haematol.2018.210963
https://doi.org/10.3324/haematol.2018.210963
Autor:
David C. Williams, Gordon D. Ginder
Publikováno v:
Pharmacology & Therapeutics. 184:98-111
DNA methylation represents a fundamental epigenetic modification that regulates chromatin architecture and gene transcription. Many diseases, including cancer, show aberrant methylation patterns that contribute to the disease phenotype. DNA methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0279709c94ae01686ce7207647e4bad6
https://doi.org/10.1016/j.pharmthera.2017.11.002
https://doi.org/10.1016/j.pharmthera.2017.11.002
Autor:
Sunny Kim, Bernard F. Fuemmler, David C. Wheeler, Carrie A. Miller, Yaou Sheng, Tamas S Gal, Bonnie Morris, Gordon D. Ginder, Bassam Dahman
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:A30-A30
Purpose of the Study: Traditionally, population-based health assessments have been conducted through resource intensive approaches such as in-person interviews and mail-based surveys. Newer information technologies have been developed for collecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24352c6beacd499ace956973a54ca6e9
https://doi.org/10.1158/1538-7755.modpop19-a30
https://doi.org/10.1158/1538-7755.modpop19-a30
Publikováno v:
Cancer Research. 80:82-82
Acute myeloid and T-cell acute lymphoblastic leukemia are aggressive subtypes of acute leukemias with 5-year survival rates ranging from 10% to 50%. CHD4, the ATPase chromatin re-modeling component of the NuRD co-repressor complex, has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20201d12dec207b679e6e88d4a6cdbc8
https://doi.org/10.1158/1538-7445.am2020-82
https://doi.org/10.1158/1538-7445.am2020-82
Autor:
David C. Williams, Gordon D. Ginder
Publikováno v:
Pharmacologytherapeutics. 190
DNA methylation represents a fundamental epigenetic modification that regulates chromatin architecture and gene transcription. Many diseases, including cancer, show aberrant methylation patterns that contribute to the disease phenotype. DNA methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a838cd72efac9f0df2d40cceb05fc044
https://pubmed.ncbi.nlm.nih.gov/29128342
https://pubmed.ncbi.nlm.nih.gov/29128342