Zobrazeno 1 - 10
of 23 562
pro vyhledávání: '"Gordon D"'
Autor:
Jennifer L. Reedy, Kirstine Nolling Jensen, Arianne J. Crossen, Kyle J. Basham, Rebecca A. Ward, Christopher M. Reardon, Hannah Brown Harding, Olivia W. Hepworth, Patricia Simaku, Geneva N. Kwaku, Kazuya Tone, Janet A. Willment, Delyth M. Reid, Mark H. T. Stappers, Gordon D. Brown, Jayaraj Rajagopal, Jatin M. Vyas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Respiratory infections caused by the human fungal pathogen Aspergillus fumigatus are a major cause of mortality for immunocompromised patients. Exposure to these pathogens occurs through inhalation, although the role of the respiratory epith
Externí odkaz:
https://doaj.org/article/e6887f3ec8884f338db33021a03541eb
Autor:
Qinxi Ma, Arnab Pradhan, Ian Leaves, Emer Hickey, Elena Roselletti, Ivy Dambuza, Daniel E. Larcombe, Leandro Jose de Assis, Duncan Wilson, Lars P. Erwig, Mihai G. Netea, Delma S. Childers, Gordon D. Brown, Neil A.R. Gow, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 11, Iss , Pp 100128- (2024)
Host recognition of the pathogen-associated molecular pattern (PAMP), β-1,3-glucan, plays a major role in antifungal immunity. β-1,3-glucan is an essential component of the inner cell wall of the opportunistic pathogen Candida albicans. Most β-1,3
Externí odkaz:
https://doaj.org/article/246a9682c09641f7a0a0fda1cc487324
Autor:
Vanessa I. Francis, Corin Liddle, Emma Camacho, Madhura Kulkarni, Samuel R. S. Junior, Jamie A. Harvey, Elizabeth R. Ballou, Darren D. Thomson, Gordon D. Brown, J. Marie Hardwick, Arturo Casadevall, Jonathan Witton, Carolina Coelho
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTCryptococcus neoformans causes lethal meningitis and accounts for approximately 10%–15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of how this fungus invades the mammalian brain. To investigate the dynami
Externí odkaz:
https://doaj.org/article/fc389f2ba9944567b613ee2209d651cc
Autor:
Alexander K. Lancaster, Richard M. Single, Steven J. Mack, Vanessa Sochat, Michael P. Mariani, Gordon D. Webster
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Python for Population Genomics (PyPop) is a software package that processes genotype and allele data and performs large-scale population genetic analyses on highly polymorphic multi-locus genotype data. In particular, PyPop tests data conformity to H
Externí odkaz:
https://doaj.org/article/be39c84a44ef4727a564110bf1bb8b67
Autor:
Gabriela M. Avelar, Arnab Pradhan, Qinxi Ma, Emer Hickey, Ian Leaves, Corin Liddle, Alejandra V. Rodriguez Rondon, Ann-Kristin Kaune, Sophie Shaw, Corinne Maufrais, Natacha Sertour, Judith M. Bain, Daniel E. Larcombe, Leandro J. de Assis, Mihai G. Netea, Carol A. Munro, Delma S. Childers, Lars P. Erwig, Gordon D. Brown, Neil A. R. Gow, Marie-Elisabeth Bougnoux, Christophe d'Enfert, Alistair J. P. Brown
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our immune defenses. These strategies include the masking of immunoinflammatory pathog
Externí odkaz:
https://doaj.org/article/a315d65d8db7474e9c59617b6af6132d
Autor:
Amanda O'Brien, Alastair Hayton, Keith Cutler, Andy Adler, Darren J Shaw, John Clarke, Neil Watt, Gordon D Harkiss
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301609 (2024)
Bovine tuberculosis is usually diagnosed using tuberculin skin tests or at post-mortem. Recently, we have developed a serological test for bovine tuberculosis in cattle which shows a high degree of accuracy using serum samples. Here, we have assessed
Externí odkaz:
https://doaj.org/article/5602460308254363b601cccdaeade959
Autor:
Maxine A Höft, Lucian Duvenage, Sumayah Salie, Roanne Keeton, Alfred Botha, Ilan S Schwartz, Nelesh P Govender, Gordon D Brown, Jennifer Claire Hoving
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011850 (2024)
Emergomyces africanus is a recently identified thermally-dimorphic fungal pathogen that causes disseminated infection in people living with advanced HIV disease. Known as emergomycosis, this disseminated disease is associated with very high case fata
Externí odkaz:
https://doaj.org/article/92df4c38f3e8466b8ab764c391f6c015
Publikováno v:
Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Objective Dysregulated appetite control is characteristic of anorexia nervosa (AN), bulimia nervosa (BN), and obesity (OB). Studies using a broad range of methods suggest the cerebellum plays an important role in aspects of weight and appeti
Externí odkaz:
https://doaj.org/article/24ce2c0bc7b949f59f6f02a4fc0ac9d4
Autor:
Marissa H. Forbes, Gordon D. Hoople
Publikováno v:
Trends in Higher Education, Vol 2, Iss 2, Pp 291-305 (2023)
Community-partnered engineering projects provide a mechanism for cultivating the development of sociotechnical engineers prepared to design within diverse and complex cultural, environmental, social, and other contexts. During the 2021–2022 academi
Externí odkaz:
https://doaj.org/article/9d304874e5514019924e12eea7c6bfea
Autor:
Amanda O’Brien, John Clarke, Alastair Hayton, Andy Adler, Keith Cutler, Darren J. Shaw, Clare Whelan, Neil J. Watt, Gordon D. Harkiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Bovine tuberculosis is a contagious bacterial disease of worldwide economic, zoonotic and welfare importance caused mainly by Mycobacterium bovis infection. Current regulatory diagnostic methods lack sensitivity and require improvement. We h
Externí odkaz:
https://doaj.org/article/90a7bb19f53044e5b646b9028d6217de