Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Gordon B. Cutler"'
Autor:
Diana Ponce, Fernando Rodríguez, José P. Miranda, Alexandra M. Binder, José L. Santos, Karin B. Michels, Gordon B. Cutler, Ana Pereira, Germán Iñiguez, Verónica Mericq
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Biochemical premature adrenarche is defined by elevated serum DHEAS [≥40 μg/dL] before age 8 y in girls. This condition is receiving more attention due to its association with obesity, hyperinsulinemia, dyslipidemia, and polycystic ovary syndrome.
Externí odkaz:
https://doaj.org/article/7428a6c1936f4beaa926de779c9b4405
Autor:
Werner F. Blum, Jürgen Klammt, Serge Amselem, Heike M. Pfäffle, Marie Legendre, Marie-Laure Sobrier, Marie-Pierre Luton, Christopher J. Child, Christine Jones, Alan G. Zimmermann, Charmian A. Quigley, Gordon B. Cutler, Jr, Cheri L. Deal, Jan Lebl, Ron G. Rosenfeld, John S. Parks, Roland W. Pfäffle
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 390-400 (2018)
Background: Pituitary development and GH secretion are orchestrated by multiple genes including GH1, GHRHR, GLI2, HESX1, LHX3, LHX4, PROP1, POU1F1, and SOX3. We aimed to assess their mutation frequency and clinical relevance in children with severe G
Externí odkaz:
https://doaj.org/article/eb38d45a2af84fb1a420e9f01ae4ca4c
Autor:
Ana Pereira, José P. Miranda, Verónica Mericq, José Luis Santos, Gordon B. Cutler, Camila Corvalán, Fernando Rodríguez, María Cecilia Lardone
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:e1727-e1738
Context Adrenarche reflects the developmental growth of the adrenal zona reticularis, which produces increasing adrenal androgen secretion (eg, dehydroepiandrosterone [DHEA]/dehydroepiandrosterone sulfate [DHEAS]) from approximately age 5 to 15 years
Autor:
Ana Pereira, Paulina M. Merino, Jose L. Santos, German Iñiguez, Gordon B. Cutler, Camila Corvalan, Veronica Mericq
Publikováno v:
Clinical endocrinologyREFERENCES. 96(3)
An association between premature adrenarche and metabolic syndrome at presentation has been described. Our aim was to assess whether the presence of high dehydroepiandrosterone sulphate (DHEAS [HD]) at the adrenarche determines the risk of metabolic
Autor:
Editha D. Nottelmann, Elizabeth J. Susman, Jerome H. Blue, Gale Inoff-Germain, Lorah D. Dorn, D. Lynn Loriaux, Gordon B. Cutler, George P. Chrousos
Publikováno v:
Biological-Psychosocial Interactions in Early Adolescence ISBN: 9781003217992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93189e0197821d1189da842eb2423b6e
https://doi.org/10.4324/9781003217992-15
https://doi.org/10.4324/9781003217992-15
Publikováno v:
Journal of the Endocrine Society
Background: Hypothalamic-pituitary-gonadal (HPG) dysfunction is known to occur in male patients with Cushing Syndrome (CS) but the underlying mechanisms of HPG dysfunction remain unclear. We performed frequent blood sampling and GnRH stimulation test
Autor:
Bo Zhang, Michail S. Lionakis, Gordon B. Cutler, Monica M. Schmitt, Elise M. N. Ferré, Shangyuan Ye, Karen K. Winer
Publikováno v:
Bone. 149:115977
Objective Hypoparathyroidism has heterogeneous genetic and acquired etiologies with a broad spectrum of severity. Herein we describe the clinical outcomes of the largest cohort of hypoparathyroid patients reported to date, who were followed over 27-y
Autor:
Kupper A. Wintergerst, Werner F. Blum, Christopher J. Child, Judith L. Ross, Ron G. Rosenfeld, Wayne V. Moore, Charmian A. Quigley, Gordon B. Cutler
Publikováno v:
Hormone research in paediatrics. 91(4)
Background/Objectives: Growth hormone (GH) treatment of idiopathic short stature (ISS) received US Food and Drug Administration approval in 2003. We assessed height gain and safety in 2,450 children with ISS treated with GH in US clinical practice. M
Autor:
Marie-Laure Sobrier, Serge Amselem, Heike Pfäffle, Cheri Deal, Charmian A. Quigley, Jurgen Klammt, John S. Parks, Ron G. Rosenfeld, Alan Zimmerman, Roland Pfäffle, Gordon B. Cutler, Marie Legendre, Marie-Pierre Luton, Christine Jones, Werner F. Blum, Christopher J. Child, Jan Lebl
Publikováno v:
EBioMedicine
EBioMedicine, 2018, 36, pp.390-400. ⟨10.1016/j.ebiom.2018.09.026⟩
EBioMedicine, 2018, 36, pp.390-400. ⟨10.1016/j.ebiom.2018.09.026⟩
Background: Pituitary development and GH secretion are orchestrated by multiple genes including GH1, GHRHR, GLI2, HESX1, LHX3, LHX4, PROP1, POU1F1, and SOX3. We aimed to assess their mutation frequency and clinical relevance in children with severe G
Autor:
Cheri Deal, Charmian A. Quigley, Ron G. Rosenfeld, Alan G. Zimmermann, Gordon B. Cutler, Werner F. Blum, Christopher J. Child, Stenvert L. S. Drop
Publikováno v:
European Journal of Endocrinology, 174(5), 669-679. Bioscientifica Ltd
ObjectiveTo determine characteristics of children initially diagnosed with isolated growth hormone deficiency (IGHD) of organic aetiology, who later developed multiple pituitary hormone deficiencies (MPHD).DesignData were analysed for 716 growth horm