Zobrazeno 1 - 10
of 547
pro vyhledávání: '"Gordana Vunjak Novakovic"'
Autor:
Daniel Naveed Tavakol, Trevor R. Nash, Youngbin Kim, Pamela L. Graney, Martin Liberman, Sharon Fleischer, Roberta I. Lock, Aaron O'Donnell, Leah Andrews, Derek Ning, Keith Yeager, Andrew Harken, Naresh Deoli, Sally A. Amundson, Guy Garty, Kam W. Leong, David J. Brenner, Gordana Vunjak‐Novakovic
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Galactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during missions to the Moon and Mars. Experimental models capable of recapitulating human physiology are critical to understanding the effects of radiation
Externí odkaz:
https://doaj.org/article/7e92c8cf27d14e3786d3ad5685ed5b4e
Autor:
Alican Kuşoğlu, Deniz Örnek, Aslı Dansık, Ceren Uzun, Sena Nur Özkan, Sevgi Sarıca, Kardelen Yangın, Şevval Özdinç, Duygu Turan Sorhun, Nuriye Solcan, Efe Can Doğanalp, Øystein Arlov, Katherine Cunningham, Ismail C. Karaoğlu, Seda Kizilel, Ihsan Solaroğlu, Pınar Bulutay, Pınar Fırat, Suat Erus, Serhan Tanju, Şükrü Dilege, Gordana Vunjak‐Novakovic, Nurcan Tuncbag, Ece Öztürk
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Tumor extracellular matrices (ECM) exhibit aberrant changes in composition and mechanics compared to normal tissues. Proteoglycans (PG) are vital regulators of cellular signaling in the ECM with the ability to modulate receptor tyrosine kina
Externí odkaz:
https://doaj.org/article/a63380413b3f4842a13ba93e08720412
Autor:
Youngbin Kim, Kunlun Wang, Roberta I. Lock, Trevor R. Nash, Sharon Fleischer, Bryan Z. Wang, Barry M. Fine, Gordana Vunjak-Novakovic
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 238-249 (2024)
Goal: Contractile response and calcium handling are central to understanding cardiac function and physiology, yet existing methods of analysis to quantify these metrics are often time-consuming, prone to mistakes, or require specialized equipment/lic
Externí odkaz:
https://doaj.org/article/0364c818667741609d6dace91158f06a
Autor:
Shankar Subramaniam, Metin Akay, Mark A. Anastasio, Vasudev Bailey, David Boas, Paolo Bonato, Ashutosh Chilkoti, Jennifer R. Cochran, Vicki Colvin, Tejal A. Desai, James S. Duncan, Frederick H. Epstein, Stephanie Fraley, Cecilia Giachelli, K. Jane Grande-Allen, Jordan Green, X. Edward Guo, Isaac B. Hilton, Jay D. Humphrey, Chris R Johnson, George Karniadakis, Michael R. King, Robert F. Kirsch, Sanjay Kumar, Cato T. Laurencin, Song Li, Richard L. Lieber, Nigel Lovell, Prashant Mali, Susan S. Margulies, David F. Meaney, Brenda Ogle, Bernhard Palsson, Nicholas A. Peppas, Eric J. Perreault, Rick Rabbitt, Lori A. Setton, Lonnie D. Shea, Sanjeev G. Shroff, Kirk Shung, Andreas S. Tolias, Marjolein C.H. van der Meulen, Shyni Varghese, Gordana Vunjak-Novakovic, John A. White, Raimond Winslow, Jianyi Zhang, Kun Zhang, Charles Zukoski, Michael I. Miller
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 1-13 (2024)
Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistica
Externí odkaz:
https://doaj.org/article/99aa19c8944b4368939a87375caa3abd
Autor:
Roberta I. Lock, Pamela L. Graney, Daniel Naveed Tavakol, Trevor R. Nash, Youngbin Kim, Eloy Sanchez, Jr., Margaretha Morsink, Derek Ning, Connie Chen, Sharon Fleischer, Ilaria Baldassarri, Gordana Vunjak-Novakovic
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114302- (2024)
Summary: Resident cardiac macrophages are critical mediators of cardiac function. Despite their known importance to cardiac electrophysiology and tissue maintenance, there are currently no stem-cell-derived models of human engineered cardiac tissues
Externí odkaz:
https://doaj.org/article/5be56a0c6df041aa801ae2892eaaca68
Autor:
Josephine Y. Wu, Keith Yeager, Daniel Naveed Tavakol, Margaretha Morsink, Bryan Wang, Rajesh Kumar Soni, Clark T. Hung, Gordana Vunjak-Novakovic
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112509- (2023)
Summary: In tissue development and homeostasis, transforming growth factor (TGF)-β signaling is finely coordinated by latent forms and matrix sequestration. Optogenetics can offer precise and dynamic control of cell signaling. We report the developm
Externí odkaz:
https://doaj.org/article/72a66df3412044ab83c7f69655a5c54d
Autor:
Jiawen Chen, Seyed Mohammad Mir, Maria R. Hudock, Meghan R. Pinezich, Panpan Chen, Matthew Bacchetta, Gordana Vunjak-Novakovic, Jinho Kim
Publikováno v:
APL Bioengineering, Vol 7, Iss 1, Pp 016104-016104-14 (2023)
The airway epithelium lining the luminal surface of the respiratory tract creates a protective barrier that ensures maintenance of tissue homeostasis and prevention of respiratory diseases. The airway epithelium, unfortunately, is frequently injured
Externí odkaz:
https://doaj.org/article/5b45e8a7390049f28e1c1b5fd4af7996
Autor:
Xianghai Liao, Peter J. Kennel, Bohao Liu, Trevor R. Nash, Richard Z. Zhuang, Amandine F. Godier-Furnemont, Chenyi Xue, Rong Lu, Paolo C. Colombo, Nir Uriel, Muredach P. Reilly, Steven O. Marx, Gordana Vunjak-Novakovic, Veli K. Topkara
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Heart failure (HF) is characterized by global alterations in myocardial DNA methylation, yet little is known about the epigenetic regulation of the noncoding genome and potential reversibility of DNA methylation with left ventricular assist device (L
Externí odkaz:
https://doaj.org/article/56c323310ede495294a207d140e203cb
Autor:
Guoping Li, Tianji Chen, James Dahlman, Lola Eniola‐Adefeso, Ionita C. Ghiran, Peter Kurre, Wilbur A. Lam, Jennifer K. Lang, Eduardo Marbán, Pilar Martín, Stefan Momma, Malcolm Moos, Deborah J. Nelson, Robert L. Raffai, Xi Ren, Joost P. G. Sluijter, Shannon L. Stott, Gordana Vunjak‐Novakovic, Nykia D. Walker, Zhenjia Wang, Kenneth W. Witwer, Phillip C. Yang, Martha S. Lundberg, Margaret J. Ochocinska, Renee Wong, Guofei Zhou, Stephen Y. Chan, Saumya Das, Prithu Sundd
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids, proteins, lipids and metabolites that play versatile roles in intercellular and interorgan communication. The capability to modulate their stability, ti
Externí odkaz:
https://doaj.org/article/18fab64d303f4b96a14f506db0bcec94
Autor:
Meghan R. Pinezich, Mohammad Mir, Jonathan A. Reimer, Sarah R. Kaslow, Jiawen Chen, Brandon A. Guenthart, Matthew Bacchetta, John D. O'Neill, Gordana Vunjak‐Novakovic, Jinho Kim
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Pulmonary air leak is the most common complication of lung surgery, with air leaks that persist longer than 5 days representing a major source of post‐surgery morbidity. Clinical management of air leaks is challenging due to limited method
Externí odkaz:
https://doaj.org/article/381367de965447ddb8c74380bf68bd43