Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gord Adamson"'
Publikováno v:
Bioconjugate Chemistry. 17:530-537
A novel conjugate of human hemoglobin (Hb) and the nucleoside analogue ribavirin (RBV) was synthesized to demonstrate the utility of Hb as a biocompatible drug carrier for improved drug delivery in the treatment of liver disease. RBV is used in combi
Publikováno v:
Cancer Research. 76:2055-2055
Hepatocellular carcinoma (HCC) is the second most common cause of death from cancer worldwide; few treatment options are available, especially for advanced stage disease. Therapure has developed a novel drug delivery platform based upon the attachmen
Publikováno v:
Journal of Clinical Oncology. 34:e14061-e14061
e14061Background: Hepatocellular carcinoma (HCC) is the second most common cause of death from cancer worldwide. Current standard of care provides only a modest improvement in overall survival and ...
Autor:
Gord Adamson, Peter C.W. Kim, Thomas Engelhardt, Tal Shichor, Mark W. Crawford, David Bell, F. J. Lou Carmichael
Publikováno v:
Anesthesiology. 107(2)
Background Erythrocyte transfusion decreases morbidity in sickle cell disease, but is not without risk. Use of a hemoglobin-based oxygen carrier could offer the benefits of erythrocyte transfusion while reducing related complications. The authors tes
Autor:
Pieter Biessels, David S. Bell, M. James Phillips, Nancy Ng, Laisum Fung, Ian D. McGilvray, Gord Adamson, Caroline Woods, Reginald M. Gorczynski, Louise A. Scrocchi, Max Ma, Adam Levy, Cheryl Koscik, William He, Steve Brookes, Andrea Rowe, Gary A. Levy, Anand Ghanekar
Publikováno v:
Hepatology (Baltimore, Md.)
Side effects of interferon–ribavirin combination therapy limit the sustained viral response achievable in hepatitis C virus (HCV) patients. Coupling ribavirin to macromolecular carriers that target the drug to the liver would reduce systemic compli