Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gorazd Krosl"'
Autor:
Denis-Claude Roy, Renaud Manuguerra-GagnÉ, Vincent Pichette, Ahmed Ammar, Mark R. Lesk, Gorazd Krosl, Patrick R. Boulos, François A. Leblond
Publikováno v:
Stem Cells. 31:1136-1148
Among bone marrow cells, hematopoietic and mesenchymal components can contribute to repair damaged organs. Such cells are usually used in acute diseases but few options are available for the treatment of chronic disorders. In this study, we have used
Publikováno v:
Stem Cells and Development. 21:133-142
Members of the homeobox (Hox) gene family are known to mediate expansion of hematopoietic stem cells (HSCs) and progenitors. The absence of oncogenic properties promoted HOXB4 as prime candidate in the quest to expand HSCs for clinical purposes. Desp
Autor:
Mona Nemer, Frédéric Charron, Martin Lefrancois, Paul-Henri Roméo, Ilan R. Kirsch, Gang He, Trang Hoang, Gorazd Krosl, Paul Jolicoeur
Publikováno v:
Scopus-Elsevier
ResearcherID
The Journal of Experimental Medicine
ResearcherID
The Journal of Experimental Medicine
In normal hemopoietic cells that are dependent on specific growth factors for cell survival, the expression of the basic helix-loop-helix transcription factor SCL/Tal1 correlates with that of c-Kit, the receptor for Steel factor (SF) or stem cell fac
Autor:
Gorazd Krosl, Peter D. Aplan, Bastien Gerby, Julie Lacombe, Richard Martin, Mathieu Tremblay, Trang Hoang, Sébastien Lemieux
Publikováno v:
Blood
Blood, American Society of Hematology, 2013, 122 (7), pp.1150-1161. ⟨10.1182/blood-2011-01-331819⟩
Blood, American Society of Hematology, 2013, 122 (7), pp.1150-1161. ⟨10.1182/blood-2011-01-331819⟩
SCL/TAL1, a tissue-specific transcription factor of the basic helix-loop-helix family, and c-Kit, a tyrosine kinase receptor, control hematopoietic stem cell survival and quiescence. Here we report that SCL levels are limiting for the clonal expansio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62b663e66b6e183a9f02483b4874a03
https://hal.archives-ouvertes.fr/hal-02353626
https://hal.archives-ouvertes.fr/hal-02353626
Autor:
Gorazd Krosl, Mladen Korbelik
Publikováno v:
Cancer Letters. 84:43-49
Treatment of squamous cell carcinoma (SCCVII) bearing mice with the immunostimulant schizophyllan (SPG) raised the relative content of Mac-1 positive host cells infiltrating the tumor and increased photofrin retention in these tumors. In vitro colony
Autor:
Jean-Philippe Bastien, David S. Allan, Christian Scotto, Claude Perreault, Marissa Rashkovan, Denis-Claude Roy, Sandra Cohen, Donna E. Hogge, Gorazd Krosl, R. Maarten Egeler, Cynthia Therien
Publikováno v:
Blood, 116(23), 4859-4869
Even the most potent immunosuppressive drugs often fail to control graft-versus-host disease (GVHD), the most frequent and deleterious posttransplantation complication. We previously reported that photodepletion using dibromorhodamine (TH9402) elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d412a8d57a0e8cdebd6e6e11314b6a30
https://hdl.handle.net/1887/110051
https://hdl.handle.net/1887/110051
Publikováno v:
British Journal of Cancer
Photofrin levels in cells derived from SCCVII tumours, excised from mice that previously received the drug, were measured using a fluorescence activated cell sorter (FACS). Concomitantly, in the same cells the FACS was used to measure fluorescein iso
Autor:
Claude Perreault, Denis-Claude Roy, Luc Villeneuve, N. Dallaire, B. Antonia, Gordon J. Freeman, Gorazd Krosl
Publikováno v:
Biology of Blood and Marrow Transplantation. 9(2)
Publikováno v:
Biology of Blood and Marrow Transplantation. 13(2):72-73
Publikováno v:
Oncogene. 16(26)
The products of PBX homeobox genes, which were initially discovered in reciprocal translocations occurring in human leukemias, have been shown to cooperate in the in vitro DNA binding with HOX proteins. Despite the growing body of data implicating Ho