COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA

Autor: Macintyre, Geoff, Goranova, Teodora E., De Silva, Dilrini, Ennis, Darren, Piskorz, Anna M., Eldridge, Matthew, Sie, Daoud, Lewsley, Liz-Anne, Hanif, Aishah, Wilson, Cheryl, Dowson, Suzanne, Glasspool, Rosalind M., Lockley, Michelle, Brockbank, Elly, Montes, Ana, Walther, Axel, Sundar, Sudha, Edmondson, Richard, Hall, Geoff D., Clamp, Andrew, Gourley, Charlie, Hall, Marcia, Fotopoulou, Christina, Gabra, Hani, Paul, James, Supernat, Anna, Millan, David, Hoyle, Aoisha, Bryson, Gareth, Nourse, Craig, Mincarelli, Laura, Sanchez, Luis Navarro, Ylstra, Bauke, Jimenez-Linan, Mercedes, Moore, Luiza, Hofmann, Oliver, Markowetz, Florian, McNeish, Iain A., Brenton, James D.

Publikováno v: Clinical Cancer Research, 25(22), 64-64. American Association for Cancer Research Inc.
Macintyre, G, Goranova, T E, De Silva, D, Ennis, D, Piskorz, A M, Eldridge, M, Sie, D, Lewsley, L-A, Hanif, A, Wilson, C, Dowson, S, Glasspool, R M, Lockley, M, Brockbank, E, Montes, A, Walther, A, Sundar, S, Edmondson, R, Hall, G D, Clamp, A, Gourley, C, Hall, M, Fotopoulou, C, Gabra, H, Paul, J, Supernat, A, Millan, D, Hoyle, A, Bryson, G, Nourse, C, Mincarelli, L, Sanchez, L N, Ylstra, B, Jimenez-Linan, M, Moore, L, Hofmann, O, Markowetz, F, McNeish, I A & Brenton, J D 2019, ' COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA ', Clinical Cancer Research, vol. 25, no. 22, pp. 64-64 .

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https://research.vumc.nl/en/publications/25d8187b-e9c2-4916-84b7-202a59425cca

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Copy number signatures and mutational processes in ovarian carcinoma

Autor: Geoff Macintyre, Charlie Gourley, Richard J. Edmondson, Bauke Ylstra, Marcia Hall, Elly Brockbank, David Millan, Iain A. McNeish, Rosalind Glasspool, Christina Fotopoulou, Suzanne Dowson, Anna M. Piskorz, Aoisha Hoyle, Mercedes Jimenez-Linan, Matthew D. Eldridge, Daoud Sie, Luiza Moore, Liz Anne Lewsley, Teodora Goranova, Hani Gabra, James Paul, Darren Ennis, Gareth Bryson, Sudha Sundar, Cheryl Wilson, Laura Mincarelli, Ana Montes, Anna Supernat, D.G.H. de Silva, Andrew R Clamp, Florian Markowetz, Oliver Hofmann, Axel Walther, Aishah Hanif, Craig Nourse, Luis Navarro Sanchez, Michelle Lockley, James D. Brenton, Geoff Hall

Publikováno v: Macintyre, G, Goranova, T E, De Silva, D, Ennis, D, Piskorz, A M, Eldridge, M, Sie, D, Lewsley, L, Hanif, A, Wilson, C, Dowson, S, Glasspool, R M, Lockley, M, Brockbank, E, Montes, A, Walther, A, Sundar, S, Edmondson, R, Hall, G D, Clamp, A, Gourley, C, Hall, M, Fotopoulou, C, Gabra, H, Paul, J, Supernat, A, Millan, D, Hoyle, A, Bryson, G, Nourse, C, Mincarelli, L, Sanchez, L N, Ylstra, B, Jimenez-linan, M, Moore, L, Hofmann, O, Markowetz, F, Mcneish, I A & Brenton, J D 2018, ' Copy number signatures and mutational processes in ovarian carcinoma ', Nature Genetics, vol. 50, no. 9, pp. 1262-1270 . https://doi.org/10.1038/s41588-018-0179-8
Nature genetics
Macintyre, G, Goranova, T E, De Silva, D, Ennis, D, Piskorz, A M, Eldridge, M, Sie, D, Lewsley, L, Hanif, A, Wilson, C, Dowson, S, Glasspool, R M, Lockley, M, Brockbank, E, Montes, A, Walther, A, Sundar, S, Edmondson, R, Hall, G D, Clamp, A, Gourley, C, Hall, M, Fotopoulou, C, Gabra, H, Paul, J, Supernat, A, Millan, D, Hoyle, A, Bryson, G, Nourse, C, Mincarelli, L, Sanchez, L N, Ylstra, B, Jimenez-linan, M, Moore, L, Hofmann, O, Markowetz, F, Mcneish, I A & Brenton, J D 2018, ' Copy number signatures and mutational processes in ovarian carcinoma ', Nature Genetics . https://doi.org/10.1038/s41588-018-0179-8
Nature Genetics, 50(9), 1262-1270. Nature Publishing Group
Macintyre, G, Goranova, T E, De Silva, D, Ennis, D, Piskorz, A M, Eldridge, M, Sie, D, Lewsley, L A, Hanif, A, Wilson, C, Dowson, S, Glasspool, R M, Lockley, M, Brockbank, E, Montes, A, Walther, A, Sundar, S, Edmondson, R, Hall, G D, Clamp, A, Gourley, C, Hall, M, Fotopoulou, C, Gabra, H, Paul, J, Supernat, A, Millan, D, Hoyle, A, Bryson, G, Nourse, C, Mincarelli, L, Sanchez, L N, Ylstra, B, Jimenez-Linan, M, Moore, L, Hofmann, O, Markowetz, F, McNeish, I A & Brenton, J D 2018, ' Copy number signatures and mutational processes in ovarian carcinoma ', Nature Genetics, vol. 50, no. 9, pp. 1262-1270 . https://doi.org/10.1038/s41588-018-0179-8

Tumours with profound copy-number aberration elude molecular stratification due to their genomic complexity. By representing this complexity as a mixture of copy-number signatures, we provide molecular explanations for differing clinical outcomes. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cad4ec47a8550b4094fe0acd8079e4f
https://research.manchester.ac.uk/en/publications/d5c55e20-60ab-4f6f-ac90-f9d0e7bb6dc2