Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Goran Poje"'
Autor:
Jaka Dernovšek, Živa Zajec, Goran Poje, Dunja Urbančič, Caterina Sturtzel, Tjaša Goričan, Sarah Grissenberger, Krzesimir Ciura, Mateusz Woziński, Marius Gedgaudas, Asta Zubrienė, Simona Golič Grdadolnik, Irena Mlinarič-Raščan, Zrinka Rajić, Andrej Emanuel Cotman, Nace Zidar, Martin Distel, Tihomir Tomašič
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116941- (2024)
The development of new anticancer agents is one of the most urgent topics in drug discovery. Inhibition of molecular chaperone Hsp90 stands out as an approach that affects various oncogenic proteins in different types of cancer. These proteins rely o
Externí odkaz:
https://doaj.org/article/483114562b034ad18b22bbfe461393c1
Publikováno v:
Molecules, Vol 26, Iss 21, p 6490 (2021)
As cancer remains one of the major health burdens worldwide, novel agents, due to the development of resistance, are needed. In this work, we designed and synthesized harmirins, which are hybrid compounds comprising harmine and coumarin scaffolds, ev
Externí odkaz:
https://doaj.org/article/2aca02e9304f479aa5431c7f2e0e1f54
Autor:
Goran Poje, Marina Marinović, Kristina Pavić, Marija Mioč, Marijeta Kralj, Lais Pessanha de Carvalho, Jana Held, Ivana Perković, Zrinka Rajić
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9315
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cancer and malaria are both global health threats. Due to the increase in the resistance to the known drugs, research on new active substances is a priority. Here, we present the design, synthesis, and evaluation of the biological activity of harmice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c43a32c20b8d750b489745c88a423cb
Autor:
Goran Poje, Lais Pessanha de Carvalho, Jana Held, Diana Moita, Miguel Prudêncio, Ivana Perković, Tana Tandarić, Robert Vianello, Zrinka Rajić
Publikováno v:
European Journal of Medicinal Chemistry. 238:114408
© 2022 Elsevier Masson SAS. All rights reserved.
Malaria remains one of the major health problems worldwide. The lack of an effective vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs demands the development
Malaria remains one of the major health problems worldwide. The lack of an effective vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs demands the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07cd27e295efc74d6dfb44c75867cd6
https://doi.org/10.1016/j.ejmech.2022.114408
https://doi.org/10.1016/j.ejmech.2022.114408