Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gopinath C. Nallani"'
Autor:
Appavu Chandrasekaran, Shaaban F. ElNaggar, Kelem Kassahun, Gopinath C. Nallani, Zhiwei Liu, Li Shen
Publikováno v:
Toxicology and Applied Pharmacology. 338:65-72
Bifenthrin, a pyrethroid insecticide, undergoes oxidative metabolism leading to the formation of 4'-hydroxy-bifenthrin (4'-OH-BIF) and hydrolysis leading to the formation of TFP acid in rat and human hepatic microsomes. In this study, age-dependent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a90a7ff2f5d167ddfeea378b9b1821
https://doi.org/10.1016/j.taap.2017.11.010
https://doi.org/10.1016/j.taap.2017.11.010
Publikováno v:
Regulatory Toxicology and Pharmacology. 84:26-34
The in vitro comparative animal metabolism study is now a data requirement under EU Directive 1107/2009 for registration of plant protection products. This type of study helps determine the extent of metabolism of a chemical in each surrogate species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd0a25520b5456960e167ab39688ed25
https://doi.org/10.1016/j.yrtph.2016.12.006
https://doi.org/10.1016/j.yrtph.2016.12.006
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 110
Following adoption of the new OECD test guideline (TG) 474 for the in vivo mammalian erythrocyte micronucleus (MN) test (29 July 2016), demonstration of exposure of target tissue (bone marrow) is required, if the test result is negative i.e. no cytog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd502a1e8eb022292a119b98696d2b9
https://pubmed.ncbi.nlm.nih.gov/31836537
https://pubmed.ncbi.nlm.nih.gov/31836537
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 96:580-584
Evaluation of the environmental risk of human pharmaceuticals is now a mandatory component in all new drug applications submitted for approval in EU. With >3000 drugs currently in use, it is not feasible to test each active ingredient, so prioritizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070bda8ec9bee4bf3049e613526b72b7
https://doi.org/10.1007/s00128-016-1782-y
https://doi.org/10.1007/s00128-016-1782-y
Autor:
Gopinath C. Nallani, Regina Edziyie, Lisa A. Constantine, Barney J. Venables, Peter M. Paulos, Duane B. Huggett
Publikováno v:
Environmental Toxicology and Chemistry. 35:593-603
The present study examined the bioconcentration of 2 basic pharmaceuticals: verapamil (a calcium channel blocker) and clozapine (an antipsychotic compound) in 2 fresh water fishes, fathead minnow and channel catfish. In 4 separate bioconcentration fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe188ac2ed6342adf3e1176ffad542bf
https://doi.org/10.1002/etc.3244
https://doi.org/10.1002/etc.3244
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 84
The in vitro comparative animal metabolism study is now a data requirement under EU Directive 1107/2009 for registration of plant protection products. This type of study helps determine the extent of metabolism of a chemical in each surrogate species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67010ee4aa64bbb5a486278daf3c9260
https://pubmed.ncbi.nlm.nih.gov/27993653
https://pubmed.ncbi.nlm.nih.gov/27993653
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 152:232-240
We examined the acute effects of triclosan (TCS) exposure, a common antimicrobial found as a contaminant in the field, on survival and physiology of amphibian larvae. LC50 values were determined after 96 h for North American larval species: Acris cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45c91d395a54bb0c100a3ea48985b39
https://doi.org/10.1016/j.cbpc.2010.04.009
https://doi.org/10.1016/j.cbpc.2010.04.009
Autor:
Gopinath C, Nallani, Regina E, Edziyie, Peter M, Paulos, Barney J, Venables, Lisa A, Constantine, Duane B, Huggett
Publikováno v:
Environmental toxicology and chemistry. 35(3)
The present study examined the bioconcentration of 2 basic pharmaceuticals: verapamil (a calcium channel blocker) and clozapine (an antipsychotic compound) in 2 fresh water fishes, fathead minnow and channel catfish. In 4 separate bioconcentration fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd80bfcf63ef135257045473c484dca9
https://pubmed.ncbi.nlm.nih.gov/26753615
https://pubmed.ncbi.nlm.nih.gov/26753615
Autor:
Gopinath C. Nallani, Peter M. Paulos, Lisa A. Constantine, Barney J. Venables, Regina Edziyie, Duane B. Huggett
Publikováno v:
Archives of environmental contamination and toxicology. 62(2)
The environmental presence of the oral contraceptive norethindrone (NET) has been reported and shown to have reproductive effects in fish at environmentally realistic exposure levels. The current study examined bioconcentration potential of NET in fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87be4264e9e689ae17df518386982c
https://pubmed.ncbi.nlm.nih.gov/21710293
https://pubmed.ncbi.nlm.nih.gov/21710293
Autor:
Barney J. Venables, Gopinath C. Nallani, Peter M. Paulos, Lisa A. Constantine, Duane B. Huggett
Publikováno v:
Chemosphere. 84(10)
Pharmaceutical products and their metabolites are being widely detected in aquatic environments and there is a growing interest in assessing potential risks of these substances to fish and other non-target species. Ibuprofen is one of the most common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da63980defbd6c36358c3f11e384594
https://pubmed.ncbi.nlm.nih.gov/21658739
https://pubmed.ncbi.nlm.nih.gov/21658739