Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Gopinath, Prakasam"'
Publikováno v:
Cancer Drug Resistance. :182-204
The context-dependent reciprocal interaction between the cancer cells and surrounding fibroblasts is imperative for regulating malignant potential, metabolic reprogramming, immunosuppression, and ECM deposition. However, recent evidence also suggests
Autor:
Farid Ahmad Siddiqui, Gopinath Prakasam, Shilpi Chattopadhyay, Asad Ur Rehman, Rayees Ahmad Padder, Mohammad Afaque Ansari, Rasha Irshad, Kailash Mangalhara, Rameshwar N. K. Bamezai, Mohammad Husain, Syed Mansoor Ali, Mohammad Askandar Iqbal
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its role in affecting cancer metabolism remains poorly understood.
Externí odkaz:
https://doaj.org/article/a4e44a22eac149e0a5bfdd849c908dfc
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Here we demonstrate localization of the isoform3 of DNA Methyltransferase1 (DNMT1) enzyme to mitochondria, instead of isoform1 as reported earlier. The fused DNMT1-isoform1, reported earlier to localize in mitochondria, surprisingly showed i
Externí odkaz:
https://doaj.org/article/05a5af99ff31489f98ba8f2624253fd6
Autor:
Gopinath Prakasam, Mohammad Askandar Iqbal, Anusha Srivastava, Rameshwar N. K. Bamezai, Rajnish Kumar Singh
Publikováno v:
VirusDisease. 33:223-235
The molecular basis of human papillomavirus (HPV)-mediated cellular immortalization and malignant transformation has illustrated an indispensable role of viral E6/E7-oncoproteins. However, the impact of viral-oncoproteins on the metabolic phenotype o
Autor:
Chaman, Noor, Iqbal, Mohammad Askandar, Siddiqui, Farid Ahmad, Gopinath, Prakasam, Bamezai, Rameshwar N.K.
Publikováno v:
In Journal of Biological Chemistry 25 September 2015 290(39):23803-23815
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Cancer cells rewire metabolism to meet biosynthetic and energetic demands. The characteristic increase in glycolysis, i.e., Warburg effect, now considered as a hallmark, supports cancer in various ways. To attain such metabolic reshuffle, cancer cell
Externí odkaz:
https://doaj.org/article/1c89ac05359f4306bb3765ec38b54a4d
Autor:
Iqbal, Mohd Askandar, Gupta, Vibhor, Gopinath, Prakasam, Mazurek, Sybille, Bamezai, Rameshwar N.K.
Publikováno v:
In FEBS Letters 19 August 2014 588(16):2685-2692
Autor:
Iqbal, Mohd Askandar, Siddiqui, Farid Ahmad, Chaman, Noor, Gupta, Vibhor, Kumar, Bhupender, Gopinath, Prakasam, Bamezai, Rameshwar N.K.
Publikováno v:
In Journal of Biological Chemistry 14 March 2014 289(12):8098-8105
Autor:
Shivashankar Kengadaran, Srisakthi. D., M Kavitha, Divvi Anusha, Gopinath Prakasam, Vigneshwari. S.K
Publikováno v:
Research Journal of Pharmacy and Technology. :2224-2228
Introduction: Nosocomial infections are caused by the retrograde spread of viral, bacterial and fungal pathogens from the hospital environment to the patients. Despite the efforts to avoid cross-infection in the dental office using sterilized instrum
Publikováno v:
Molecular Aspects of Medicine. 70:3-20
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of therapy throughout the world. Clinical success of therapies is not very promising due to - late diagnosis, limited therapeutic tools, relapse and the development o