Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gopika Nandagopal"'
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S6. TCGA LUAD methylation at the LINC00261 locus. A. Individual CpGs are denoted by their Illumina 450K designation. Scale = 0 (no methylation) to 1 (complete methylation). Hg19-based coordinates for each probe are listed below the cg ascensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f74c1e04365ab6e86923cc40c9da42e
https://doi.org/10.1158/0008-5472.22420773.v1
https://doi.org/10.1158/0008-5472.22420773.v1
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S1. Bioinformatic analysis of differential lncRNA expression in LUAD. A. Table of samples included in the initial analysis. AEC = Alveolar Epithelial Cells. B. Volcano plot of differential analysis for lncRNA expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c73b8ed09e10aa5aca733de9d086a78
https://doi.org/10.1158/0008-5472.22420788
https://doi.org/10.1158/0008-5472.22420788
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S5. Gene expression analysis of LINC00261 co-regulated genes. A. Overlap between H522 differentially expressed genes. Blue circle = Differentially expressed genes in H522 RNAseq. Purple circle = genes co-expressed with LINC00261 in TCGA LUAD (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bad54c5b2e8abf40439269c24b78dc
https://doi.org/10.1158/0008-5472.22420776.v1
https://doi.org/10.1158/0008-5472.22420776.v1
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Lung cancer is the leading cause of cancer-related death in the United States. Long noncoding RNAs (lncRNA) are a class of regulatory molecules whose role in lung carcinogenesis is poorly understood. In this study, we profiled lncRNA expression in lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be5c8c99fb924cdb07f977cf9b218e1
https://doi.org/10.1158/0008-5472.c.6510753
https://doi.org/10.1158/0008-5472.c.6510753
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S2. Further analysis of LINC00261 expression in multiple cancer types. A. Stratification of LINC00261 expression from TCGA LUSC samples based on stage at diagnosis. B. Upper panel: Overall survival of patients stratified by expression level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd5b0fd128b84f61603537c2d3b2d2e
https://doi.org/10.1158/0008-5472.22420785
https://doi.org/10.1158/0008-5472.22420785
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S3. Characterization of stable H522-CMV-LINC00261 cell lines. A. qRT-PCR levels of LINC00261 expression in H522 cells transfected with ectopic CMV-LINC00261 and CMV-NEO backbone as the control vector. Three stable cells lines of each construct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d1a59a483dd19b6492b6f2e1c4fc3f
https://doi.org/10.1158/0008-5472.22420782
https://doi.org/10.1158/0008-5472.22420782
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S7. TCGA LUAD methylation at the FOXA2 locus. A. Individual CpGs are denoted by their Illumina 450K designation. Scale = 0 (no methylation) to 1 (complete methylation). Hg19-based coordinates for each probe are listed below the cg ascension nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd35220f0c4ae53c719d95af546b67d2
https://doi.org/10.1158/0008-5472.22420770
https://doi.org/10.1158/0008-5472.22420770
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Figure S4. A. Migration of LINC00261 in A549 cell lines. The A549-shLINC00261 stable cell line and A549-shScrambled control were plated on transwell filters and measured by Violet blue staining. Statistical analysis was performed using a paired t-tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b1cc0dbbf3e8d431329e34451861b5
https://doi.org/10.1158/0008-5472.22420779.v1
https://doi.org/10.1158/0008-5472.22420779.v1
Autor:
Crystal N. Marconett, Zea Borok, Beiyun Zhou, Sean K. Lynch, Amrita Bhat, Riya Goel, Autumn Saizan, Michele Ramos Correa, Alexander Alvarado, Daniel J. Mullen, Gopika Nandagopal, Zhengmin Cong, Jonathan Castillo, Vishaly Kumaran, Shandy Shahabi
Supplemental Table T1. List of Primers for LINC00261 detection and cloning. Supplemental Table T2. Differentially expressed lncRNAs in LUAD versus primary AEC. Supplemental Table T3. Differentially expressed genes in H522-CMV-LINC00261 vs CMV-NEO con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928a8d091c67f15df0d703ff4da236c8
https://doi.org/10.1158/0008-5472.22420767
https://doi.org/10.1158/0008-5472.22420767
Autor:
Jenna G Eaton, Tyler C Hogan, Nikoletta Sidiropoulos, Cai L McCann, Hailey M. Sarausky, Kenneth J. Hampel, Gopika Nandagopal, David J. Seward, Paula B. Deming, Meagan A Lebeau, Margaret P Cameron, Jordan Armstrong, Sean M. Lenahan, Liam Donnelly
Publikováno v:
Carcinogenesis
Serine/Threonine Kinase 11 (STK11) encodes an important tumor suppressor that is frequently mutated in lung adenocarcinoma. Clinical studies have shown that mutations in STK11 resulting in loss of function correlate with resistance to anti-PD-1 monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908e3f1d41dadc767c8d25e7486fca41
https://pubmed.ncbi.nlm.nih.gov/34849607
https://pubmed.ncbi.nlm.nih.gov/34849607
