Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gopalakrishnan Mannathusamy"'
Publikováno v:
Journal of Pharmaceutical Research International. :45-54
The improved synthesis of Flecainide acetate (I) is conferred in this article. The chief intent to present this article is to identify and synthesis of the process related impurities of Flecainide acetate. The article also provides the complete study
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Publikováno v:
In Bioorganic & Medicinal Chemistry 1 August 2015 23(15):4561-4566
Autor:
Anbuselvan Chinnadurai, Gopalakrishnan Mannathusamy, Neelakandan Kaliaperumal, Prasad Pandurang Panchabhai
Publikováno v:
Journal of Pharmaceutical Research International. :139-146
The article confers a scalable manufacturing process of Fenspiride HCl. 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol is the main building block in Fenspiride HCl synthesis. The reported reagents for 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol sy
Autor:
Gopalakrishnan Mannathusamy, Neelakandan Kaliaperumal, Prasad Pandurang Panchabhai, Anbuselvan Chinnadurai
Publikováno v:
Journal of Pharmaceutical Research International. :538-547
An improved and simplified process of vitamin K1 preparation. The article confers the new reagent BF3. Acetic acid complex as a condensation reagent for phytol with compound III in vitamin K1 synthesis, which eludes the use of ethereal reagent and ma
Publikováno v:
Journal of Pharmaceutical Research International. :421-430
Commercially viable manufacturing process for Flecainide Acetate (I) conforming to regulatory specification and cost effective process is reported. Specifically, an improved process for the preparation of Flecainide Acetate allows isolation of anhydr
Development and Validation of a Diethyl Phosphite Content in Foscarnet Sodium USP by GC MS Technique
Publikováno v:
Journal of Pharmaceutical Research International. :192-201
A simple, rapid, selective, and reproducible Gas chromatographic mass spectrometry (GC-MS) method has been developed and validated for the estimation of Diethyl Phosphite content in Foscarnet Sodium USP Drug substance. The drugs were estimated using
Publikováno v:
Oriental Journal Of Chemistry. 37:321-329
The Pharmaceutical industry uses formic acid in the manufacturing of various drug substances or API. At the time of manufacturing of API formic acid is use as an oxidizing agent. Formic acid is the simplest carboxylic acid. It also called methanoic a
Publikováno v:
Oriental Journal Of Chemistry. 37:348-353
A simple, selective, precise and accurate Gas chromatographic method for determination of Triethyl orthoformate content (Genotoxic impurity) in 5-MIA is reported. The GC method development and validation as per the International Council for Harmonisa
Publikováno v:
Oriental Journal of Chemistry. 37:493-498
A simple, selective, linear having accuracy and specific of reverse phase high-performance liquid chromatographic (RP-HPLC) method for determination of Genotoxic impurity Hydroxylamine Hydrochloride of drug Leflunomide is reported.The separation and