PINK1-deficiency facilitates mitochondrial iron accumulation and colon tumorigenesis.

Autor: Arcos M; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA., Goodla L; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA., Kim H; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA., Desai SP; Department of Molecular Genetics Microbiology, University of New Mexico, Albuquerque, NM, USA., Liu R; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Yin K; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA., Liu Z; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA., Martin DR; Department of Pathology, University of New Mexico, Albuquerque, NM, USA., Xue X; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, USA.

Publikováno v: Autophagy [Autophagy] 2024 Nov 16, pp. 1-17. Date of Electronic Publication: 2024 Nov 16.

Iron promotes glycolysis to drive colon tumorigenesis.

Autor: Liu Z; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Villareal L; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Goodla L; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Kim H; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Falcon DM; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Haneef M; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA., Martin DR; Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA., Zhang L; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA., Lee HJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA., Kremer D; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA., Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA., Shah YM; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA., Lin HC; Section of Gastroenterology, Medicine Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA; Division of Gastroenterology and Hepatology, Department of Medicine, the University of New Mexico, Albuquerque, NM, 87131, USA., Lin HK; Department of Pathology, Duke University, Durham, NC 27710, USA., Xue X; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA. Electronic address: xxue@salud.unm.edu.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2023 Dec; Vol. 1869 (8), pp. 166846. Date of Electronic Publication: 2023 Aug 12.

The Role of Inflammatory Mediators in Colorectal Cancer Hepatic Metastasis.

Autor: Goodla L; Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA., Xue X; Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.

Publikováno v: Cells [Cells] 2022 Jul 27; Vol. 11 (15). Date of Electronic Publication: 2022 Jul 27.

Molecular Mechanisms of Skatole-Induced Inflammatory Responses in Intestinal Epithelial Caco-2 Cells: Implications for Colorectal Cancer and Inflammatory Bowel Disease.

Autor: Ishii, Katsunori¹ (AUTHOR), Naito, Kazuma¹ (AUTHOR), Tanaka, Dai¹ (AUTHOR), Koto, Yoshihito¹ (AUTHOR), Kurata, Koichi² (AUTHOR), Shimizu, Hidehisa^{1,2,3,4,5,6,7} (AUTHOR) hideshmz@life.shimane-u.ac.jp

Publikováno v: Cells (2073-4409). Oct2024, Vol. 13 Issue 20, p1730. 16p.

The Role of Microbial Metabolites in the Progression of Neurodegenerative Diseases—Therapeutic Approaches: A Comprehensive Review.

Autor: Missiego-Beltrán, Jorge¹ (AUTHOR) jmissiegob@alumnos.nebrija.es, Beltrán-Velasco, Ana Isabel¹ (AUTHOR) abeltranv@nebrija.es

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10041. 27p.