Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System

Autor: Goode, EC, Clark, AB, Melis, GM, Srivastava, B, Spiess, K, Gelson, WTH, Trivedi, PJ, Lynch, KD, Castren, Eero, Vesterhus, Mette, Karlsen, Tom Hemming, Ji, SG, Anderson, CA, Thorburn, Douglas, Hudson, M, Heneghan, M, Aldersley, MA, Bathgate, A, Sandford, RN, Alexander, GJ, Chapman, RW, Walmsley, M, Hirschfield, Gideon M., Rushbrook, SM

Publikováno v: Goode, EC Clark, AB Melis, GM Srivastava, B Spiess, K Gelson, WTH Trivedi, PJ Lynch, KD Castren, Eero Vesterhus, Mette Karlsen, Tom Hemming Ji, SG Anderson, CA Thorb
Hepatology

Externí odkaz: http://hdl.handle.net/10852/72724
https://www.duo.uio.no/bitstream/handle/10852/72724/1/Goode_et_al-2019-Hepatology.pdf

Reply.

Autor: Goode EC; Norfolk and Norwich University Hospital, Norwich, United Kingdom.; Academic Department of Medical Genetics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.; Norwich Medical School, University of East Anglia, Norwich, United Kingdom.; Cambridge Transplant Centre, Addenbrooke's Hospital, Cambridge, United Kingdom., Hirschfield GM; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, United Kingdom.; Institute of Immunology & Immunotherapy, University of Birmingham, Birmingham, United Kingdom.; Centre for Rare Diseases, Institute of Translational Medicine, University Hospitals Birmingham, Birmingham, United Kingdom.; Toronto Centre for Liver Disease, University Health Network and University of Toronto, Toronto, Canada., Rushbrook SM; Norfolk and Norwich University Hospital, Norwich, United Kingdom.; Norwich Medical School, University of East Anglia, Norwich, United Kingdom.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2020 Jan; Vol. 71 (1), pp. 399-400. Date of Electronic Publication: 2020 Jan 03.

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Autor: Alberts R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands., de Vries EMG; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands., Goode EC; Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Jiang X; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Sampaziotis F; Department of Surgery, Wellcome Trust-Medical Research Council Stem Cell Institute, Anne McLaren Laboratory, University of Cambridge, Cambridge, UK.; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Rombouts K; Institute for Liver and Digestive Health, University College London, Royal Free Hospital, London, UK., Böttcher K; Institute for Liver and Digestive Health, University College London, Royal Free Hospital, London, UK., Folseraas T; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Weismüller TJ; Department of Gastroenterology Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Integrated Research and Treatment Center-Transplantation (IFB-tx) Hannover Medical School, Hannover, Germany., Mason AL; Division of Gastroenterology and Hepatology, University of Alberta, Edmonton, Alberta, Canada., Wang W; Division of Gastroenterology and Hepatology, University of Alberta, Edmonton, Alberta, Canada., Alexander G; Department of Medicine, Division of Hepatology, University of Cambridge, Cambridge, UK., Alvaro D; Department of Clinical Medicine, Division of Gastroenterology, Sapienza University of Rome, Rome, Italy., Bergquist A; Center for Digestive Diseases, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Björkström NK; Department of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Beuers U; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands., Björnsson E; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Landspitali University Hospital, Reykjavik, Iceland., Boberg KM; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; K G Jebsen Inflammation Research Centre and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Bowlus CL; Division of Gastroenterology and Hepatology, University of California Davis, Davis, California, USA., Bragazzi MC; Sapienza University of Rome, Medico-Surgical Sciences and Biotechnologies, Rome, Italy., Carbone M; Department of Medicine and Surgery, Program for Autoimmune Liver Diseases, International Center for Digestive Health, University of Milan-Bicocca, Milan, Italy., Chazouillères O; Department of Hepatology, AP-HP, Hôpital Saint Antoine, Paris, France., Cheung A; General Internal Medicine, University Health Network, Toronto General Hospital, Toronto, Canada., Dalekos G; Department of Medicine and Research Laboratory of Internal Medicine, Medical School, University of Thessaly, Larissa, Greece., Eaton J; Division of Gastroenterology and Hepatology, Mayo Clinic Minnesota, Rochester, Minnesota, USA., Eksteen B; Department of Medicine, Snyder Institute of Chronic Diseases, University of Calgary, Calgary, Canada., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Färkkilä M; Department of Medicine, Division of Gastroenterology, Helsinki University Hospital, Helsinki, Finland., Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands., Floreani A; Department of Surgical Oncological and Gastroenterological Sciences, University of Padova, Padova, Italy., Franceschet I; Department of Surgery Oncology and Gastroenterology, University of Padova, Padova, Italy., Gotthardt DN; Department of Medicine, University Hospital of Heidelberg, Heidelberg, Germany., Hirschfield GM; Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham, UK., Hoek BV; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands., Holm K; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Hohenester S; Department of Medicine II, Liver Center Munich, University of Munich, Munich, Germany., Hov JR; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Imhann F; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands., Invernizzi P; Department of Medicine and Surgery, Program for Autoimmune Liver Diseases, International Center for Digestive Health, University of Milan-Bicocca, Milan, Italy., Juran BD; Division of Gastroenterology and Hepatology, Mayo Clinic Minnesota, Rochester, Minnesota, USA., Lenzen H; Department of Gastroenterology Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Lieb W; Popgen Biobank, University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.; Institute for Epidemiology, Christian-Albrechts University, Kiel, Germany., Liu JZ; Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, Cambridge, UK., Marschall HU; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden., Marzioni M; Department of Gastroenterology, Università Politecnica delle Marche, Ospedali Riuniti University Hospital, Ancona, Italy., Melum E; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Milkiewicz P; Liver and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland., Müller T; Department of Internal Medicine Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany., Pares A; Liver Unit Hospital Clinic, IDIBAPS, CIBERehd, University of Barcelona, Barcelona, Spain., Rupp C; Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Germany., Rust C; Department of Medicine I, Krankenhaus Barmherzige Brüder, Munich, Germany., Sandford RN; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Schramm C; 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Department for General Internal Medicine, Christian-Albrechts-University, Kiel, Germany., Schrumpf E; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Silverberg MS; Inflammatory Bowel Disease (IBD) Group Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital Toronto, Ontario, Canada., Srivastava B; Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Sterneck M; Department of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Teufel A; 1st Department of Medicine, University of Mainz, Mainz, Germany., Vallier L; Department of Surgery, Wellcome Trust-Medical Research Council Stem Cell Institute, Anne McLaren Laboratory, University of Cambridge, Cambridge, UK.; Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, Cambridge, UK., Verheij J; Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands., Vila AV; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands., Vries B; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands., Zachou K; Department of Internal Medicine, University of Thessaly, Larissa, Greece., Chapman RW; Department of Hepatology, John Radcliffe University Hospitals NHS Trust, Cambridge, UK., Manns MP; Department of Gastroenterology Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Integrated Research and Treatment Center-Transplantation (IFB-tx) Hannover Medical School, Hannover, Germany., Pinzani M; Institute for Liver and Digestive Health, University College London, Royal Free Hospital, London, UK., Rushbrook SM; Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK., Lazaridis KN; Division of Gastroenterology and Hepatology, Mayo Clinic Minnesota, Rochester, Minnesota, USA., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Anderson CA; Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, Cambridge, UK., Karlsen TH; Norwegian PSC Research Center, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Ponsioen CY; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands., Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.

Publikováno v: Gut [Gut] 2018 Aug; Vol. 67 (8), pp. 1517-1524. Date of Electronic Publication: 2017 Aug 04.

Activated intestinal macrophages in patients with cirrhosis release NO and IL-6 that may disrupt intestinal barrier function.

Autor: Goode EC, Warburton RC, Gelson WT, Watson AJ

Publikováno v: Gastroenterology [Gastroenterology] 2013 Dec; Vol. 145 (6), pp. 1481-4.

Mesenteric fat as a source of CRP and target for bacterial translocation in Crohn's disease.

Autor: Goode EC; Norwich Medical School, University of East Anglia, Norwich, England., Watson AJ

Publikováno v: Gastroenterology [Gastroenterology] 2012 Aug; Vol. 143 (2), pp. 496-8. Date of Electronic Publication: 2012 Jun 20.