Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Gonzalo Sanchez-Duffhues"'
Publikováno v:
SLAS Discovery, Vol 29, Iss 8, Pp 100196- (2024)
Targeting transforming growth factor-β (TGF-β) receptors is a promising pharmacological approach to normalize aberrant signaling in genetic and non-genetic TGF-β associated diseases including fibrosis, cancer, cardiovascular and musculoskeletal di
Externí odkaz:
https://doaj.org/article/26fa8b004f2a42ff99e746cff2cda2e0
Autor:
Esther Dronkers, Tessa van Herwaarden, Thomas J van Brakel, Gonzalo Sanchez-Duffhues, Marie-José Goumans, Anke M Smits
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The epicardium, the mesothelial layer covering the heart, is a crucial cell source for cardiac development and repair. It provides cells and biochemical signals to the heart to facilitate vascularization and myocardial growth. An essential element of
Externí odkaz:
https://doaj.org/article/806a16335a1a4e74b0686f399d3fb8b4
Cripto favours chondrocyte hypertrophy via TGF-beta SMAD1/5 signaling in experimental osteoarthritis
Autor:
Gonzalo Sanchez-Duffhues, Amaya Garcia de Vinuesa Antuñano, Esmeralda Blaney-Davidson, Arjan van Caam, Kirsten Lodder, Yolande Ramos, Margreet Kloppenburg, Ingrid Meulenbelt, Peter van der Kraan, Marie-José Goumans, Peter ten Dijke
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101043- (2021)
Externí odkaz:
https://doaj.org/article/c206a7ee63144358b58afee8af92efc2
Autor:
Jin Ma, Gerard van der Zon, Manuel A. F. V. Gonçalves, Maarten van Dinther, Midory Thorikay, Gonzalo Sanchez-Duffhues, Peter ten Dijke
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Endothelial-to-mesenchymal transition (EndMT) plays an important role in embryonic development and disease progression. Yet, how different members of the transforming growth factor-β (TGF-β) family regulate EndMT is not well understood. In the curr
Externí odkaz:
https://doaj.org/article/914b74b0d1ba4c118ce6cd0e59ac3223
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endothelial to mesenchymal transition (EndMT) is a complex biological process that gives rise to cells with multipotent potential. EndMT is essential for the formation of the cardiovascular system during embryonic development. Emerging results link E
Externí odkaz:
https://doaj.org/article/dc2fe5d95c544dbeb20c41ce333480ba
Autor:
Francesc Ventura, Eleanor Williams, Makoto Ikeya, Alex N. Bullock, Peter ten Dijke, Marie-José Goumans, Gonzalo Sanchez-Duffhues
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 213 (2021)
Fibrodysplasia ossificans progressiva (FOP) is an ultrarare congenital disease that progresses through intermittent episodes of bone formation at ectopic sites. FOP patients carry heterozygous gene point mutations in activin A receptor type I ACVR1,
Externí odkaz:
https://doaj.org/article/c3cde98499ca4096b050ad86f43e2375
Autor:
Songting Shi, Jie Cai, David J J de Gorter, Gonzalo Sanchez-Duffhues, Dwi U Kemaladewi, Willem M H Hoogaars, Annemieke Aartsma-Rus, Peter A C 't Hoen, Peter ten Dijke
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69096 (2013)
Fibrodysplasia ossificans progressiva (FOP) is a rare heritable disease characterized by progressive heterotopic ossification of connective tissues, for which there is presently no definite treatment. A recurrent activating mutation (c.617G→A; R206
Externí odkaz:
https://doaj.org/article/8b10ff0983c3452c99d42c526bccbfd9
Autor:
Jin Ma, Gonzalo Sanchez-Duffhues, Josselin Caradec, Pascal Benderitter, Jan Hoflack, Peter ten Dijke
Publikováno v:
Future Medicinal Chemistry. 14:389-391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b3919d7fb1ba86af9ad8afba2a43e9
https://doi.org/10.4155/fmc-2021-0342
https://doi.org/10.4155/fmc-2021-0342
Autor:
Pascal Andre Rene Benderitter, Jiang Ren, Josselin Caradec, Jan Hoflack, Gonzalo Sanchez-Duffhues, Maarten van Dinther, Midory Thorikay, Jin Ma, Peter ten Dijke
Publikováno v:
Cancers, 13(12). MDPI
Cancers
Cancers, Vol 13, Iss 2951, p 2951 (2021)
Volume 13
Issue 12
Cancers
Cancers, Vol 13, Iss 2951, p 2951 (2021)
Volume 13
Issue 12
Simple Summary Anti-angiogenesis agents have shown anti-cancer activity by preventing blood vessel ingrowth, thereby limiting tumour growth and metastasis. Although these molecules lead to prolonged overall survival of cancer patients, therapy resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc496090c118b19da4fa81b1192b93ba
https://hdl.handle.net/1887/3249669
https://hdl.handle.net/1887/3249669
Cripto favours chondrocyte hypertrophy via TGF-beta SMAD1/5 signaling in experimental osteoarthritis
Autor:
Kirsten Lodder, Ingrid Meulenbelt, Amaya Garcia de Vinuesa Antuñano, Marie-José Goumans, Yolande F M Ramos, Margreet Kloppenburg, Gonzalo Sanchez-Duffhues, Peter ten Dijke, Peter M. van der Kraan, Arjan P. M. van Caam, Esmeralda Blaney-Davidson
Publikováno v:
Bone Reports, Vol 14, Iss, Pp 101043-(2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a8351e80eb8b5cc6c0a6e4a74164ec
http://www.sciencedirect.com/science/article/pii/S2352187221002989
http://www.sciencedirect.com/science/article/pii/S2352187221002989