Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gonzalo Pérez‐Mejías"'
Autor:
Paul T. Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A. Turner, Inmaculada Márquez, Hasini A. Kalpage, Asmita Vaishnav, Matthew P. Zurek, Philipp P. Huettemann, Katherine Kim, Tasnim Arroum, Miguel A. De la Rosa, Dipanwita Dutta Chowdhury, Icksoo Lee, Joseph S. Brunzelle, Thomas H. Sanderson, Moh H. Malek, David Meierhofer, Brian F. P. Edwards, Irene Díaz-Moreno, Maik Hüttemann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational modifications of cytochrome c (Cytc) are involved in ischemia-reperfusion injury by regulating mitochondrial respiration a
Externí odkaz:
https://doaj.org/article/af1ef7e675a5418daa91f2c38dad03d0
Autor:
Alexandre M. J. Gomila, Gonzalo Pérez-Mejías, Alba Nin-Hill, Alejandra Guerra-Castellano, Laura Casas-Ferrer, Sthefany Ortiz-Tescari, Antonio Díaz-Quintana, Josep Samitier, Carme Rovira, Miguel A. De la Rosa, Irene Díaz-Moreno, Pau Gorostiza, Marina I. Giannotti, Anna Lagunas
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Electron transfer between mitochondrial cytochrome c and subunit of cytochrome bc 1 can proceed at long distance. Here the authors investigate further the mechanism and show phosphorylation regulation of the interactions between the protein partners
Externí odkaz:
https://doaj.org/article/920316e566aa4c3caedde8b39a1e3048
Autor:
Inmaculada Márquez, Gonzalo Pérez‐Mejías, Alejandra Guerra‐Castellano, José Luis Olloqui‐Sariego, Rafael Andreu, Juan José Calvente, Miguel A. De la Rosa, Irene Díaz‐Moreno
Publikováno v:
FEBS Open Bio, Vol 11, Iss 12, Pp 3304-3323 (2021)
Abstract Post‐translational modifications frequently modulate protein functions. Lysine acetylation in particular plays a key role in interactions between respiratory cytochrome c and its metabolic partners. To date, in vivo acetylation of lysines
Externí odkaz:
https://doaj.org/article/f09c544c2ba24db692de7b159c0df6a8
Autor:
Katiuska González‐Arzola, Alejandra Guerra‐Castellano, Francisco Rivero‐Rodríguez, Miguel Á. Casado‐Combreras, Gonzalo Pérez‐Mejías, Antonio Díaz‐Quintana, Irene Díaz‐Moreno, Miguel A. De la Rosa
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2418-2440 (2021)
Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually just regarded as an apoptotic trigger. However, growing evidence points to mitochondrial factors modulating nuclear functions. R
Externí odkaz:
https://doaj.org/article/a86f64852d4f4c938d2b8c3b88f9627b
Autor:
Gonzalo Pérez-Mejías, Alejandro Velázquez-Cruz, Alejandra Guerra-Castellano, Blanca Baños-Jaime, Antonio Díaz-Quintana, Katiuska González-Arzola, Miguel Ángel De la Rosa, Irene Díaz-Moreno
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1852-1863 (2020)
Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a variety of stimuli. Among these modifications, phosphorylation is the most ubiquitous and plays a prominent role in cell signaling.
Externí odkaz:
https://doaj.org/article/88d0d4ecc24d4b42bb29b2e1db229fe9
Autor:
Gonzalo Pérez-Mejías, Alejandra Guerra-Castellano, Antonio Díaz-Quintana, Miguel A. De la Rosa, Irene Díaz-Moreno
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 654-660 (2019)
The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies. Here, we discuss three current views—the so-ca
Externí odkaz:
https://doaj.org/article/beaaa2adce6c44149d79042251732d72
Autor:
Alejandra Guerra-Castellano, Inmaculada Márquez, Gonzalo Pérez-Mejías, Antonio Díaz-Quintana, Miguel A. De la Rosa, Irene Díaz-Moreno
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8483 (2020)
Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several human pathologies, including neurodegenerative diseases, cardiovascular diseases, and various types of cancer. In mitochondrial metabolism, cytochrome c is a
Externí odkaz:
https://doaj.org/article/c4f24f4edcab4973844da0a2a4285034
Autor:
Michele Marongiu, Gonzalo Pérez-Mejías, Valeria Orrù, Maristella Steri, Carlo Sidore, Antonio Díaz-Quintana, Antonella Mulas, Fabio Busonero, Andrea Maschio, Klaudia Walter, Manuel Tardaguila, Parsa Akbari, Nicole Soranzo, Edoardo Fiorillo, Myriam Gorospe, David Schlessinger, Irene Díaz-Moreno, Francesco Cucca, Magdalena Zoledziewska
Publikováno v:
Human Molecular Genetics.
Few genome-wide association studies (GWAS) analyzing genetic regulation of morphological traits of white blood cells have been reported. We carried out a GWAS of 12 morphological traits in 869 individuals from the general population of Sardinia, Ital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fc6d6cdbaf26396a20404df733f5c3
https://doi.org/10.1093/hmg/ddac238
https://doi.org/10.1093/hmg/ddac238
Autor:
Antonio Díaz-Quintana, Miguel A. De la Rosa, Blanca Baños-Jaime, Irene Díaz-Moreno, Alejandro Velázquez-Cruz, Alejandra Guerra-Castellano, Katiuska González-Arzola, Gonzalo Pérez-Mejías
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1852-1863 (2020)
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Computational and Structural Biotechnology Journal
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Computational and Structural Biotechnology Journal
Graphical abstract
Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a variety of stimuli. Among these modifications, phosphorylation is the most ubiquitous and plays a prominent
Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a variety of stimuli. Among these modifications, phosphorylation is the most ubiquitous and plays a prominent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb97340a2a264667bc3c13ea24e48b16
http://www.sciencedirect.com/science/article/pii/S2001037020303329
http://www.sciencedirect.com/science/article/pii/S2001037020303329
Autor:
José Luis Olloqui-Sariego, Gonzalo Pérez-Mejías, Inmaculada Márquez, Alejandra Guerra-Castellano, Juan José Calvente, Miguel A. De la Rosa, Rafael Andreu, Irene Díaz-Moreno
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1863(7)
Post-translational modifications and naturally occurring mutations of cytochrome c have been recognized as a regulatory mechanism to control its biology. In this work, we investigate the effect of such in vivo chemical modifications of human cytochro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac3e7d6a71b42d5190ab54cdc1b45f5
https://pubmed.ncbi.nlm.nih.gov/35643148
https://pubmed.ncbi.nlm.nih.gov/35643148