Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Gonzalo Martínez De la Escalera"'
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313328 (2024)
Reactive oxygen species (ROS) are physiological byproducts of neuronal metabolism. However, an imbalance between ROS generation and antioxidant capacity, often driven by dysregulated pro-oxidant enzymes like nicotinamide adenine dinucleotide phosphat
Externí odkaz:
https://doaj.org/article/1635210f922146508b8a82742cb628e4
Autor:
Dina I Vázquez-Carrillo, Ana Luisa Ocampo-Ruiz, Arelí Báez-Meza, Gabriela Ramírez-Hernández, Elva Adán-Castro, José Fernando García-Rodrigo, José Luis Dena-Beltrán, Ericka A de Los Ríos, Magdalena Karina Sánchez-Martínez, María Georgina Ortiz, Gonzalo Martínez de la Escalera, Carmen Clapp, Yazmín Macotela
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301496 (2024)
Obesity leads to insulin resistance (IR) and type 2 diabetes. In humans, low levels of the hormone prolactin (PRL) correlate with IR, adipose tissue (AT) dysfunction, and increased prevalence of T2D. In obese rats, PRL treatment promotes insulin sens
Externí odkaz:
https://doaj.org/article/9a80d8680f7f4b20978b4679eb54e47d
Autor:
Yazmín Macotela, Xarubet Ruiz-Herrera, Dina I. Vázquez-Carrillo, Gabriela Ramírez-Hernandez, Gonzalo Martínez de la Escalera, Carmen Clapp
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The role of prolactin (PRL) favoring metabolic homeostasis is supported by multiple preclinical and clinical studies. PRL levels are key to explaining the direction of its actions. In contrast with the negative outcomes associated with very high (>10
Externí odkaz:
https://doaj.org/article/11e72a6794b24cf494da85fd8f77f168
Autor:
Ivan Luzardo-Ocampo, Ana Luisa Ocampo-Ruiz, José Luis Dena-Beltrán, Gonzalo Martínez de la Escalera, Carmen Clapp, Yazmín Macotela
Publikováno v:
Nutrients, Vol 15, Iss 15, p 3447 (2023)
Maternal milk supports offspring development by providing microbiota, macronutrients, micronutrients, immune factors, and hormones. The hormone prolactin (PRL) is an important milk component with protective effects against metabolic diseases. Because
Externí odkaz:
https://doaj.org/article/216963132c594c80abcf4f425dbcc54a
Autor:
Carmen Clapp, Georgina Ortiz, Jose F. García-Rodrigo, María G. Ledesma-Colunga, Oscar F. Martínez-Díaz, Norma Adán, Gonzalo Martínez de la Escalera
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The term inflammatory arthritis defines a family of diseases, including rheumatoid arthritis (RA), caused by an overactive immune system, and influenced by host aspects including sex, reproductive state, and stress. Prolactin (PRL) is a sexually dimo
Externí odkaz:
https://doaj.org/article/3b8872ee9ec542ef8ef7aeb7feca8dd4
Autor:
Nils Müller, Juan Pablo Robles, Magdalena Zamora, Johannes Ebnet, Hülya Markl-Hahn, Gonzalo Martínez de la Escalera, Carmen Clapp, Thomas Bertsch, Jakob Triebel
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Vasoinhibin is a protein hormone with antiangiogenic, antivasodilatatory, and antivasopermeability effects generated by the proteolytic cleavage of prolactin. The discovery of its role in diabetic retinopathy and peripartum cardiomyopathy led to the
Externí odkaz:
https://doaj.org/article/7a461c7fde2b4b44a20329dd963db685
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2020)
Preeclampsia is a hypertensive disorder affecting 3–5% of all pregnancies. The only curative treatment is delivery of the placenta and the pathophysiology is poorly understood. Studies have demonstrated altered levels of antiangiogenic factors in p
Externí odkaz:
https://doaj.org/article/4485d8e930ef4d74abfab9c1187b3a62
Autor:
Maria G. Ledesma-Colunga, Norma Adán, Georgina Ortiz, Mariana Solís-Gutiérrez, Fernando López-Barrera, Gonzalo Martínez de la Escalera, Carmen Clapp
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-16 (2017)
Abstract Background Prolactin (PRL) reduces joint inflammation, pannus formation, and bone destruction in rats with polyarticular adjuvant-induced arthritis (AIA). Here, we investigate the mechanism of PRL protection against bone loss in AIA and in m
Externí odkaz:
https://doaj.org/article/23930d7dcc264a84a87a18dbfefdbc8a
Autor:
Jakob Triebel, Juan Pablo Robles, Magdalena Zamora, Gonzalo Martínez de la Escalera, Thomas Bertsch, Carmen Clapp
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/cbd6afe164e3418d80bbd13375a70e32
Autor:
Ma. Ludivina Robles-Osorio, Renata García-Franco, Carlos D. Núñez-Amaro, Ximena Mira-Lorenzo, Paulina Ramírez-Neria, Wendy Hernández, Ellery López-Star, Thomas Bertsch, Gonzalo Martínez de la Escalera, Jakob Triebel, Carmen Clapp
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
BackgroundDiabetic retinopathy (DR) and diabetic macular edema (DME) are potentially blinding, microvascular retinal diseases in people with diabetes mellitus. Preclinical studies support a protective role of the hormone prolactin (PRL) due to its oc
Externí odkaz:
https://doaj.org/article/746ff60147bb43f69a7319253c12df2c