Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gonzalo Gonzalez-Paez"'
Autor:
Gregory M. Martin, Jonathan L. Torres, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re’em Moskovitz, Nathan Beutler, Diana D. Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S. MacGill, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson, Andrew B. Ward
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The generation of high-quality antibody responses to Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP), the primary surface antigen of Pf sporozoites, is paramount to the development of an effective malaria vaccine. Here we present
Externí odkaz:
https://doaj.org/article/9852dbd3db8d470488cfc46ea2bb7db5
Autor:
Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Gonzalo Gonzalez-Paez, Zhen Han, Katherine L. Williams, Wayne Volkmuth, Daniel Emerling, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The most advanced P. falciparum circumsporozoite protein (PfCSP)-based malaria vaccine confers partial protection. Here, Pholcharee et al. present crystal structures, binding affinities/kinetics, and in vivo protection of 8 anti-NANP antibodies to un
Externí odkaz:
https://doaj.org/article/f69e762087b34c9ba0a1c8a3d1c005e9
Autor:
Gregory M. Martin, Jonathan L. Torres, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re’em Moskovitz, Nathan Beutler, Diana D. Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S. MacGill, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson, Andrew B. Ward
SummaryThe generation of high-quality antibody responses to PfCSP, the primary surface antigen ofPlasmodium falciparumsporozoites, is paramount to the development of an effective malaria vaccine. Here we present an in-depth structural and functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb053e331c24ed3ee28494413ef4b54
https://doi.org/10.1101/2022.09.20.508747
https://doi.org/10.1101/2022.09.20.508747